Hydroxyurea or hydroxycarbamide (the latter being the recommended International Non-Proprietary Name), (brand names include Hydrea®) is an antineoplastic drug used in hematological malignancies. It is also used as an antiretroviral agent (e.g., against HIV). Its mechanism of action is believed to be based on its inhibition of the enzyme ribonucleotide reductase.

Uses

---

• Polycythemia vera
• Chronic myelogenous leukemia
• Essential thrombocytosis
• Sickle-cell disease (selectively breaks down cells that are prone to sickle, as well as increasing fetal hemoglobin content)
• AIDS as an adjunct to ddI in combination antiretroviral therapies
• Biochemical research as an agent that causes ribonucleotide depletion and results in DNA double strand breaks near replication forks (see DNA repair)

Dose

---

500 milligrams once or twice a day, or more if pancytopenia does not develop.

More on [ Hydroxyurea ]

Hydroxyurea - Twitter Search

Fluorouracil, Hydroxyurea, Cetuximab and Twice-Daily Intensity Radiation Therapy for Advanced Head and Neck Cancer http://bit.ly/2ZQ4Ua
trialscentral (Trials Central) Mon, 26 Oct 2009 17:14:28 -0000
Fluorouracil, Hydroxyurea, Cetuximab and Twice-Daily Intensity Radiation Therapy for Advanced Head and Neck Cancer http://bit.ly/2ZQ4Ua
Fluorouracil, Hydroxyurea, Cetuximab and Twice-Daily Intensity Radiation Therapy for Advanced Head and Neck Cancer http://bit.ly/2mBM1t
trialscentral (Trials Central) Mon, 26 Oct 2009 17:03:54 -0000
Fluorouracil, Hydroxyurea, Cetuximab and Twice-Daily Intensity Radiation Therapy for Advanced Head and Neck Cancer http://bit.ly/2mBM1t
Hola everyone...Thanks 4 educating the Sickle Cell Community about Hydroxyurea....I like to learn about sickle... http://bit.ly/2lpIxA
Mylessicklecell (Myles) Mon, 26 Oct 2009 00:10:55 -0000
Hola everyone...Thanks 4 educating the Sickle Cell Community about Hydroxyurea....I like to learn about sickle... http://bit.ly/2lpIxA
Hola everyone....I have heard of the drug Hydroxyurea...However i am not currently on daily medication 4 my sickle... http://bit.ly/ffckU
Mylessicklecell (Myles) Sun, 25 Oct 2009 15:32:07 -0000
Hola everyone....I have heard of the drug Hydroxyurea...However i am not currently on daily medication 4 my sickle... http://bit.ly/ffckU
I'm taking pills called hydroxyurea , its suppose to reduce the amount of sickle cell crisis I have but they make me feel like shit.
Caseem (Caseem) Fri, 23 Oct 2009 02:04:48 -0000
I'm taking pills called hydroxyurea , its suppose to reduce the amount of sickle cell crisis I have but they make me feel like shit.

Subscribe to Hydroxyurea RSS feed