Hydromorphone is a drug used to relieve moderate to severe pain. Hydromorphone is known by the trade name "Dilaudid®", though an extended-release version called Palladone® SR was available for a short time before being pulled from the market in July 2005 due to a high overdose potential when taken with alcohol (still available in the UK as of April 2006). It belongs to a category of drugs known as opioid agonists. It is commonly given to patients who have recently undergone surgery or who have suffered serious injury, and it is given intravenously, intramuscularly, rectally, or orally. Hydromorphone is often sought after by opiate drug abusers as it is one of the most potent of all prescription narcotics, when taken parenterally.

Available Forms

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1. Tablets
   • 2 mg
   • 4 mg
   • 8 mg
2. Capsules (Palladone)
   • 1.3 mg
   • 2.6 mg
3. Modified Release capsules (Palladone SR)
   • 2 mg
   • 4 mg
   • 8 mg
   • 16 mg
   • 24 mg
4. Suppository
   • 3 mg
5. Powder for injection
   • 250 mg (hydromorphone HCl)
6. Oral liquid (HCl)
   • 1 mg/mL (480 mL)
7. Injection (HCl)
   • 1 mg/mL (1 mL)
   • 2 mg/mL (1 mL, 20 mL)
   • 4 mg/mL (1 mL)
   • Dilaudid-HP®
     • 10mg/ml (1 mL, 5mL, 50mL)

Details

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Hydromorphone, a semi-synthetic μ-opioid agonist, is a hydrogenated ketone of morphine and shares the pharmacologic properties typical of opioid analgesics. Hydromorphone and related opioids produce their major effects on the central nervous system and gastrointestinal tract. These include analgesia, drowsiness, mental clouding, changes in mood, euphoria or dysphoria, respiratory depression, cough suppression, decreased gastrointestinal motility, nausea, vomiting, increased cerebrospinal fluid pressure, increased biliary pressure, pinpoint constriction of the pupils, increased parasympathetic activity and transient hyperglycemia. When injected, particularly intravenously, hydromorphone produces more intense contraction sensation in the muscles and a more powerful 'rush' than other opioids, even more so than heroin (diacetylmorphine).

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Hydromorphone - Twitter Search

Nothings more fulfilling than having your pt have high BP because of pain administering hydromorphone and the BP go down =) #nursingstudent
BaskinAlaskin (Hillary Heater) Fri, 10 Feb 2012 02:39:21 -0000
Nothings more fulfilling than having your pt have high BP because of pain administering hydromorphone and the BP go down =) #nursingstudent
RT @SafeMedUse: Sign up for ISMP Canada free webinar on Hydromorphone: Discovering What We Don't Know http://t.co/cBooIsAM #ptsafety
Patient_Safety (CPSI - ICSP) Thu, 09 Feb 2012 16:35:32 -0000
RT @SafeMedUse: Sign up for ISMP Canada free webinar on Hydromorphone: Discovering What We Don't Know http://t.co/cBooIsAM #ptsafety
@AbsolutTwilight hydromorphone?
LckyRoll7 (#GFYSLoveBug ) Thu, 09 Feb 2012 16:32:52 -0000
@AbsolutTwilight hydromorphone?
Sign up for ISMP Canada free webinar on Hydromorphone: Discovering What We Don't Know http://t.co/cBooIsAM #ptsafety
SafeMedUse (Safe Medication Use) Thu, 09 Feb 2012 16:20:18 -0000
Sign up for ISMP Canada free webinar on Hydromorphone: Discovering What We Don't Know http://t.co/cBooIsAM #ptsafety
Word!RT @ChopperInMyCar: Switch to Percs or the hydromorphone asap. RT @_NatalieMariee: @ChopperInMyCar these vicodins make me like
_NatalieMariee (natalie rozay) Thu, 09 Feb 2012 06:29:25 -0000
Word!RT @ChopperInMyCar: Switch to Percs or the hydromorphone asap. RT @_NatalieMariee: @ChopperInMyCar these vicodins make me like
Switch to Percs or the hydromorphone asap. RT @_NatalieMariee: @ChopperInMyCar Lmaoo I knowww! I told you these vicodins make me like
ChopperInMyCar (Alex Sanchez) Thu, 09 Feb 2012 06:28:17 -0000
Switch to Percs or the hydromorphone asap. RT @_NatalieMariee: @ChopperInMyCar Lmaoo I knowww! I told you these vicodins make me like

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