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Cortisol is a corticosteroid hormone produced by the adrenal cortex that is involved in the response to stress; it increases blood pressure, blood sugar levels, may cause infertility in women, and suppresses the immune system. Synthetic cortisol, also known as hydrocortisone, is used as a drug mainly to fight allergies and inflammation.

Synthesis


Cortisol is synthesized from pregnenolone. The conversion involves hydroxylation of C-11, C-17, and C-21, the oxidation of C-3, and the isomerization of the C-5 double bond to C-4. The synthesis takes place in the zona fasciculata of the cortex of the adrenal glands. While the adrenal cortex also produces aldosterone (in the zona glomerulosa) and some sex hormones (in the zona reticulosa), cortisol is its main secretion. (The name cortisol comes from cortex.) The medulla of the adrenal gland lies under the cortex and mainly secretes epinephrine and norepinephrine under sympathetic stimulation.

The synthesis of cortisol in the adrenal gland is stimulated by the anterior lobe of the pituitary gland with adrenocorticotropic hormone (ACTH); production of ACTH is in turn stimulated by corticotropin-releasing hormone (CRH), released by the hypothalamus.

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@KimKardashian run your fingers through cold water for 15 mins. then put some hydrocortisone cream on the burn.
hellokitty7989 (melissa mendoza) Mon, 04 Jan 2010 04:35:10 -0000
@KimKardashian run your fingers through cold water for 15 mins. then put some hydrocortisone cream on the burn.
Hydrocortisone Cream Side Effects for Eczema Sufferers: Very often if you visit the dermatologist about your e.. http://bit.ly/6TwI1V
traceyedwards (Tracey Edwards) Mon, 04 Jan 2010 03:06:02 -0000
Hydrocortisone Cream Side Effects for Eczema Sufferers: Very often if you visit the dermatologist about your e.. http://bit.ly/6TwI1V
@KimKardashian hydrocortisone cream!
missbeccax3 (Rebecca Brazzle) Mon, 04 Jan 2010 01:46:53 -0000
@KimKardashian hydrocortisone cream!
@tomboy_femme hydrocortisone cream? thanks, good to know, i use lotion on them but it doesn't work... just prevents, doesn't cure
wilhelminawang (Wilhelmina Wang) Sun, 03 Jan 2010 20:26:09 -0000
@tomboy_femme hydrocortisone cream? thanks, good to know, i use lotion on them but it doesn't work... just prevents, doesn't cure
Narcotic painkillers are a blessing. My back pain is still there, just nicely fogged by the hydrocortisone. #fb
zanshin (mark nichols) Sun, 03 Jan 2010 19:10:58 -0000
Narcotic painkillers are a blessing. My back pain is still there, just nicely fogged by the hydrocortisone. #fb
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dbaruel (Baruel Donley) Sun, 03 Jan 2010 11:36:00 -0000
Bleeding Hemorrhoid Treatment - Ways To Get Rid Of Hemorrhoids …: Hydrocortisone creams can be bought over the .. http://bit.ly/80L0h2

 
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DrugDigest: Hydrocortisone Rectal - Information on dosage, usage, side effects, interactions, and drug comparisons including generics when available.

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