Gourt > Health > Pharmacy > Drugs and Medications > H > Heparin
Heparin is a highly sulfated glycosaminoglycan widely used as an injectable anticoagulant. It is also used to form an inner anticoagulant surface on various experimental and medical devices such as test tubes and renal dialysis machines. Pharmaceutical grade heparin is commonly derived from the tissue of slaughter house animals e.g. porcine intestine or bovine lung..
History
Heparin is one of the oldest drugs currently still in widespread clinical use. Its introduction predates the establishment of the United States Food and Drug Administration.. It was originally isolated from liver cells, hence its name (hepar or "ηπαρ" is Greek for "liver"). Scientists were looking for an anticoagulant that could work safely in humans, and Jay McLean, a second-year medical student from Johns Hopkins University working under the guidance of William Henry Howell, found a compound extracted from liver that acted as an anticoagulant.
Medical uses
Heparin acts as an anticoagulant, preventing the formation of clots and extension of existing clots within the blood. While heparin does not break down clots that have already formed, it allows the body's natural clot lysis mechanisms to work normally to break down clots that have already formed. Heparin is used for anticoagulation for the following conditions:
- Acute coronary syndrome, e.g., myocardial infarction
- Atrial fibrillation
- Deep-vein thrombosis and pulmonary embolism.
Blood Coagulation Disorders
Thrombosis :: Vascular Disorders
Latest legal Articles submitted to Targetlaw: "Fentanyl Overdose" and "Heparin Overdose" by Phyllis Lile-King http://bit.ly/6UsjSy
Targetlaw (Targetlaw) Thu, 07 Jan 2010 14:03:51 -0000
Latest legal Articles submitted to Targetlaw: "Fentanyl Overdose" and "Heparin Overdose" by Phyllis Lile-King http://bit.ly/6UsjSy
Int Med: Bleeding After Percutaneous Coronary Intervention With Bivalirudin or Unfractionated Heparin and One-Year Mort http://url4.eu/14IPl
MDLinx (Sandeep Pulim MD) Thu, 07 Jan 2010 11:31:00 -0000
Int Med: Bleeding After Percutaneous Coronary Intervention With Bivalirudin or Unfractionated Heparin and One-Year Mort http://url4.eu/14IPl
Cardio: Bleeding After Percutaneous Coronary Intervention With Bivalirudin or Unfractionated Heparin and One-Year Morta http://url4.eu/14G8V
MDLinx (Sandeep Pulim MD) Thu, 07 Jan 2010 09:29:35 -0000
Cardio: Bleeding After Percutaneous Coronary Intervention With Bivalirudin or Unfractionated Heparin and One-Year Morta http://url4.eu/14G8V
New Post on IVTEAM - Heparin flush lawsuit - you can find it here http://www.ivteam.com/heparin-flush-lawsuit/
ivteam (IVTEAM) Wed, 06 Jan 2010 22:56:20 -0000
New Post on IVTEAM - Heparin flush lawsuit - you can find it here http://www.ivteam.com/heparin-flush-lawsuit/
Heparin-based nanoparticles.: Heparin-based nanoparticles. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2... http://bit.ly/75jufT
regenmd (Ankur Gupta) Wed, 06 Jan 2010 17:16:50 -0000
Heparin-based nanoparticles.: Heparin-based nanoparticles. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2... http://bit.ly/75jufT
New lawsuit accuses a tainted dose of the blood thinner heparin for causing a Texas man's death; Other suits also filed http://bit.ly/8vX1SV
attorneyatlaw1 (Attorney at Law) Wed, 06 Jan 2010 16:50:13 -0000
New lawsuit accuses a tainted dose of the blood thinner heparin for causing a Texas man's death; Other suits also filed http://bit.ly/8vX1SV
Antithrombotics - Heparin - Information and resources about the drug from KU-W MedEd Online.
Celsus - Manufacturer of heparin and heparin-like glycosaminoglycans including Centaxarin (ardeparin sodium). Features scientific background and history.
Meta Description: [ A GMP-Manufacturer of heparin and other glycosaminoglycans. Celsus Laboratories is a USDA-approved, FDA-audited drug establishment with the capacity to manufacture and test GAGs. ]
Centaxarin - Ardeparin sodium. Features history and chemical data.
Meta Description: [ A GMP-Manufacturer of heparin and other glycosaminoglycans. Celsus Laboratories is a USDA-approved, FDA-audited drug establishment with the capacity to manufacture and test GAGs. ]
DrugDigest: Heparin - Information on dosage, usage, side effects, interactions, and drug comparisons for the low molecular weight form of the drug.
Heparins in the New Millennium: Will Unfractionated Heparin Survive? - A comprehensive discussion of the history and future of unfractionated heparin versus low molecular weight heparins. [Requires free Medscape membership]
Innohep - Prescribing information for US residents in PDF format. [Acrobat Reader required]
Innohep - Tinzaparin sodium. Features product information as well as descriptions of deep vein thrombosis and pulmonary embolisms.
Meta Description: [ LEO Pharma ]
Low Molecular Weight Heparins - Questions and answers from the Food and Drug Administration.
Low Molecular Weight Heparins in Medicine and Anaesthesia - Compares LMW and unfractionated heparins and offers information, uses, study results, and recommendations.
Venous Thromboembolism and Low-Molecular-Weight Heparins: New Treatment Options - Discussion of the uses of LMW heparins in the treatment of thromboembolic events.
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