Haloperidol (sold as Aloperidin®, Bioperidolo®, Brotopon®, Dozic®, Duraperidol® (Germany), Einalon S®, Eukystol®, Haldol®, Halosten®, Keselan®, Linton®, Peluces®, Serenace®, Serenase®, Sigaperidol®) is a conventional butyrophenone antipsychotic drug. It was developed in 1957 by the Belgian company Janssen Pharmaceutica and submitted to first clinical trials in Belgium in the same year. After being rejected by U.S. company Searle due to side effects, it was later marketed in the U.S. by McNeil Laboratories.

Chemistry

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Haloperidol is an odourless white to yellow crystalline powder. Its chemical name is 4-^*-4'-fluorobutyrophenone and its empirical formula is C₂₁H₂₃ClFNO₂

Pharmacology

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