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Granisetron is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Its main affect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors.
Granisetron was developed by chemists working at the British drug company Beecham around 1988 and is expected to go generic in 2007/2008. It is produced by Roche Laboratories under the trade name Kytril®. The drug was approved in the United Kingdom in 1991 and in United States in 1994 by the FDA.
Granisetron breaks down slowly, staying in the body for a long time. One dose usually lasts 4 to 9 hours and is usually administered once or twice daily. This drug is removed from the body by the liver and kidneys.
More on [ Granisetron ]
Use of granisetron transdermal system in the prevention of chemotherapy-induced nausea and vomiting: a review http://bit.ly/7zeVKR
DovePress (Dove Press) Thu, 17 Dec 2009 09:27:39 -0000
Use of granisetron transdermal system in the prevention of chemotherapy-induced nausea and vomiting: a review http://bit.ly/7zeVKR
News: Almac Discovery Announce Commencement Of Phase I Trials Of Granisetron Nasal Spray http://bit.ly/7lQgMV
biocompare (Biocompare) Wed, 16 Dec 2009 17:52:56 -0000
News: Almac Discovery Announce Commencement Of Phase I Trials Of Granisetron Nasal Spray http://bit.ly/7lQgMV
Almac Discovery Announce Commencement Of Phase I Trials Of Granisetron Nasal Spray: Almac Discovery announced the s... http://bit.ly/61qlNO
zampbioworld (zampbioworld) Wed, 16 Dec 2009 13:35:02 -0000
Almac Discovery Announce Commencement Of Phase I Trials Of Granisetron Nasal Spray: Almac Discovery announced the s... http://bit.ly/61qlNO
Canada Meds Almac Discovery Announce Commencement Of Phase I Trials Of Granisetron Nasal Spray: Almac Discovery ann... http://bit.ly/7qDx33
CanadaMeds (Pharmacy) Wed, 16 Dec 2009 13:16:44 -0000
Canada Meds Almac Discovery Announce Commencement Of Phase I Trials Of Granisetron Nasal Spray: Almac Discovery ann... http://bit.ly/7qDx33
Almac Discovery Announce Commencement Of Phase I Trials Of Granisetron Nasal Spray http://mnt.to/3vxH
mnt_clinical (MNT Clinical Trials) Wed, 16 Dec 2009 12:12:31 -0000
Almac Discovery Announce Commencement Of Phase I Trials Of Granisetron Nasal Spray http://mnt.to/3vxH
Almac Discovery Announce Commencement Of Phase I Trials Of Granisetron Nasal Spray http://mnt.to/3vxH
mnt_cancer (MNT Cancer News) Wed, 16 Dec 2009 12:12:30 -0000
Almac Discovery Announce Commencement Of Phase I Trials Of Granisetron Nasal Spray http://mnt.to/3vxH
Granisetron - Familydoctor.org - Information for patients in English and Spanish.
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