Glucagon is a 29-amino acid polypeptide acting as an important hormone in carbohydrate metabolism. The polypeptide has a molecular weight of 3485 daltons and was discovered in 1923 by Kimball and Murlin.

Its primary structure is: NH₂-His-Ser-Gln-Gly-Thr-Phe- Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser- Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu- Met-Asn-Thr-COOH

History

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In the 1920s, Kimball and Murlin studied pancreatic extracts and found an additional substance with hyperglycemic properties. Glucagon was sequenced in the late-1950s, but a more complete understanding of its role in physiology and disease was not established until the 1970s, when a specific radioimmunoassay was developed.

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RT @WRY999: Obesity trial supports effectiveness of liraglutide, a new glucagon-like drug. http://ow.ly/AeOv
TAWOP (Justin Marley) Sat, 07 Nov 2009 18:48:51 -0000
RT @WRY999: Obesity trial supports effectiveness of liraglutide, a new glucagon-like drug. http://ow.ly/AeOv
Obesity trial supports effectiveness of liraglutide, a new glucagon-like drug. http://ow.ly/AeOv
WRY999 (Bill Yates) Sat, 07 Nov 2009 15:18:29 -0000
Obesity trial supports effectiveness of liraglutide, a new glucagon-like drug. http://ow.ly/AeOv
Insulin, Glucagon and Diabetes: Diabetic Neuropathies - What Are They?: Insulin, Glucagon and Diabetes . Inform.. http://bit.ly/4AgOLS
nikksalva (Nikkaman Salvador) Sat, 07 Nov 2009 01:09:56 -0000
Insulin, Glucagon and Diabetes: Diabetic Neuropathies - What Are They?: Insulin, Glucagon and Diabetes . Inform.. http://bit.ly/4AgOLS
CHECKLIST FOR TRAVELING WITH INSULIN: Ketone test strips. Glucagon. Glucose tabs or gel, Lifesavers, or other c.. http://bit.ly/TvqQI
webuyteststrips (Doug Renz) Fri, 06 Nov 2009 18:09:08 -0000
CHECKLIST FOR TRAVELING WITH INSULIN: Ketone test strips. Glucagon. Glucose tabs or gel, Lifesavers, or other c.. http://bit.ly/TvqQI
@JaniniR Insuline zet glucose om in glycogeen, glucagon en adrenaline zet dat weer terug naar glucose
enonoid (Edwin Jungman) Thu, 05 Nov 2009 10:24:41 -0000
@JaniniR Insuline zet glucose om in glycogeen, glucagon en adrenaline zet dat weer terug naar glucose
New German #paleo #zone blog entry, Der menschliche Stoffwechsel: Eiweiße und Glucagon - http://tinyurl.com/yga4tm2
FelixKitchen (Felix) Thu, 05 Nov 2009 09:19:17 -0000
New German #paleo #zone blog entry, Der menschliche Stoffwechsel: Eiweiße und Glucagon - http://tinyurl.com/yga4tm2

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