Gabapentin (brand name: Neurontin^®) was initially synthesized to mimic the structure of GABA for the treatment of epilepsy. Nowadays, gabapentin has been widely used as a medication to relieve pain, especially neuropathic pain. Gabapentin is well tolerated in most patients, has a relatively mild side-effect profile, and passes through the body unmetabolized.

Gabapentin is similar in structure to the neurotransmitter GABA but is not believed to act on the same brain receptors. Its exact mechanism of action is unknown, but its therapeutic action on neuropathic pain is thought to involve voltage-gated calcium ion channels.

Clinical uses

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Gabapentin was originally approved by the FDA as an antiseizure medication. It is not effective for patients with absence seizures.

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Has anyone used gabapentin for fibromyalgia?
MavenCentral (Maven Central) Fri, 11 Dec 2009 09:07:51 -0000
Has anyone used gabapentin for fibromyalgia?
2400mg of Gabapentin is not good for the body. But the upside is making me emotionally numb. Now just a bunch of Melatonin and then bed.
jskennedy19 (Joseph Kennedy) Fri, 11 Dec 2009 04:33:25 -0000
2400mg of Gabapentin is not good for the body. But the upside is making me emotionally numb. Now just a bunch of Melatonin and then bed.
@maggieperez GABAPENTIN-it doesnt fuck you up, its just kinda weird
pbohls (Parker Bohls) Fri, 11 Dec 2009 01:44:22 -0000
@maggieperez GABAPENTIN-it doesnt fuck you up, its just kinda weird
@maggieperez its called gabapentin
pbohls (Parker Bohls) Fri, 11 Dec 2009 01:11:10 -0000
@maggieperez its called gabapentin
Why do I feel so knacked & exhausted? O ye, I took Gabapentin to numb up. It's worked. Just want to sleep now, which won't help productivity
tadbarker (tad) Thu, 10 Dec 2009 14:28:42 -0000
Why do I feel so knacked & exhausted? O ye, I took Gabapentin to numb up. It's worked. Just want to sleep now, which won't help productivity
comp of oral gabapentin & pregabalin in postoperative pain control after photorefractive ker8ctomy http://bit.ly/5TSteF
paidtrials (US Clinical Trials) Thu, 10 Dec 2009 05:46:56 -0000
comp of oral gabapentin & pregabalin in postoperative pain control after photorefractive ker8ctomy http://bit.ly/5TSteF

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