Formoterol (INN) or eformoterol (former BAN) is a long-acting β₂-agonist used in the management of asthma and/or chronic obstructive pulmonary disease (COPD). It is marketed in both dry-powder inhaler (DPI) and metered dose inhaler (MDI) preparations, under various trade names including Foradil/Foradile (Novartis) and Oxis (AstraZeneca).

Formoterol is a long-acting β₂ agonist (LABA), which has an extended duration of action (up to 12 hours) compared to short-acting β₂ agonists such as salbutamol, which have are effective for 4–6 hours. LABAs such as formoterol are used as "symptom controllers" to supplement "preventer" corticosteroid therapy (e.g. fluticasone). A "reliever" short-acting β₂ agonist (e.g. salbutamol) is still required, since LABAs are not recommended for the treatment of acute asthma.

Inhaled formoterol works like other β₂-agonists, causing bronchodilatation by relaxing the smooth muscle in the airway so as to treat the exacerbation of asthma. The long duration of formoterol action occurs because the formoterol molecules initially diffuse into the plasma membrane of the lung cells, and then are slowly released back outside, where they can come into contact with β₂ adrenergic receptors. Formoterol has been demonstrated to have a faster onset of action than salmeterol as a result of lower lipophilicity, and has also been demonstrated to be more potent - a 12 µg dose of formoterol has been demonstrated to be equivalent to a 50 µg dose of salmeterol.

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My #ACAAI story #7 is up now too: Rapid, Sustained Improvement in Airflow With Budesonide/Formoterol for COPD http://tinyurl.com/yabolsd
DeborahBrauser (Deborah Brauser) Fri, 20 Nov 2009 04:42:57 -0000
My #ACAAI story #7 is up now too: Rapid, Sustained Improvement in Airflow With Budesonide/Formoterol for COPD http://tinyurl.com/yabolsd
[-data on asthma control using budesonide/formoterol for both maintenance and relief: the swiss experience.] http://tinyurl.com/yg6swvq
healthtopicsaz (Health Topics A-Z) Thu, 19 Nov 2009 17:24:04 -0000
[-data on asthma control using budesonide/formoterol for both maintenance and relief: the swiss experience.] http://tinyurl.com/yg6swvq
Mometasone Plus Formoterol Appears Safe in Severe Persistent Asthma: Presented ... http://bit.ly/2X0We4
GraceBarkwell (GraceBarkwell) Fri, 13 Nov 2009 22:59:09 -0000
Mometasone Plus Formoterol Appears Safe in Severe Persistent Asthma: Presented ... http://bit.ly/2X0We4
Mometasone Plus Formoterol Appears Safe in Severe Persistent Asthma: Presented ... http://bit.ly/1g757M
HealAllDiseases (Madison Cavanaugh) Fri, 13 Nov 2009 22:07:53 -0000
Mometasone Plus Formoterol Appears Safe in Severe Persistent Asthma: Presented ... http://bit.ly/1g757M
Mometasone Plus Formoterol Appears Safe in Severe Persistent ... http://bit.ly/3HTzUV
YeastHoncho (Thery Zavala) Fri, 13 Nov 2009 22:02:28 -0000
Mometasone Plus Formoterol Appears Safe in Severe Persistent ... http://bit.ly/3HTzUV
Budesonide Plus Formoterol Superior to Budesonide Monotherapy for Asthma ... http://bit.ly/1AyMig
HealAllDiseases (Madison Cavanaugh) Fri, 13 Nov 2009 19:10:16 -0000
Budesonide Plus Formoterol Superior to Budesonide Monotherapy for Asthma ... http://bit.ly/1AyMig

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