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Fenofibrate is a drug of the fibrate class. It is mainly used to reduce cholesterol levels in patients at risk of cardiovascular disease. Like other fibrates, it reduces both low-density lipoprotein (LDL) and very low density lipoprotein (VLDL) levels, as well as increasing high-density liporotein (HDL) levels. It also appears to have a beneficial affect on the insulin resistance featured by the metabolic syndrome. It is used alone or in conjunction with statins in the treatment of hypercholesterolemia and hypertriglyceridemia. Fenofibrate is sold under the brand name TriCor® by Abbott Laboratories.

The pharmaceutical form and the strength may change from one country from another, in the United States it is available in tablets at 54, 107 and 160 mg. In Europe, it is available in coated tablet but also in capsule, the strength range include 67, 145, 160 and 200 mg. The differences in strength belong is due to altered bioavailability (the fraction absorbed by the body) due to particle size. For example: 200 mg can be replaced by 160 mg because its fenofibrate is micronised. The 145 mg strength is a new strength appeared in 2005-2006 which also replaces 200 or 160 mg as the fenofibrate is nanonised (ie the particle size is below 400 nm).

Like the other fibrates, fenofibrate acts on PPARα to reduce cholesterol levels.

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Fenofibrate is a medication #prescribed to reduce triglycerides in the blood. http://t.co/srVl1f12 #drug
ManuraNanayakka (Manura Nanayakkara) Sat, 31 Dec 2011 10:01:09 -0000
Fenofibrate is a medication #prescribed to reduce triglycerides in the blood. http://t.co/srVl1f12 #drug
Side effects of fenofibrate http://t.co/TfcfXi3L
njnuwantha (Dr Nuwan Nanayakkara) Sat, 31 Dec 2011 09:39:23 -0000
Side effects of fenofibrate http://t.co/TfcfXi3L
Benefits and Safety of Long-Term Fenofibrate Therapy in People With Type 2 Diabetes and Renal Impairment: Th http://t.co/zNqLa6ix #diabetes
diabeticmart (Diabetic) Sat, 31 Dec 2011 06:00:10 -0000
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Tricor Tablets - Offers cholesterol and lipid management information for patient and physician.

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