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Felodipine is a calcium channel blocker (calcium antagonist), a drug used to control hypertension (high blood pressure). It is marketed with the brand name Plendil by AstraZeneca.

Recent findings have suggested that Felodipine in combination with Grapefruit Juice can cause abnormal (toxic) effects. Oral administration of Felodipine is first metabolized in the gastrointestinal tract (GI) and liver by CYP3A4. Grapefruit Juice is found to have an inhibiting effect over Cytochrome P450 3A4. As a result the bioavailability of the drug and area under de curve (AUC) increase, increasing the risk for abnormal side effects. Therefore, special caution must me taken when mixing Grapefruit Juice with Felodipine.

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sh2d (sh2d) Fri, 10 Feb 2012 00:56:46 -0000
achat Plendil bon marche - achat Felodipine 2.5 mg tablette pharmacie: Acheter Plendil ici === PHARMACIE === Ach... http://t.co/6xzsSyiY
achat Plendil bon marche - achat Felodipine 2.5 mg tablette pharmacie: Acheter Plendil ici === PHARMACIE === Ach... http://t.co/Pqg6kcSL
Tarbiacafe1 (Tarbiacafe) Fri, 10 Feb 2012 00:56:44 -0000
achat Plendil bon marche - achat Felodipine 2.5 mg tablette pharmacie: Acheter Plendil ici === PHARMACIE === Ach... http://t.co/Pqg6kcSL
achat Plendil bon marche -
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