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Factor IX (or Christmas factor or Christmas-Eve factor) is one of the serine proteases () of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B.

Physiology


Factor IX is inactive unless activated by factor XIa (of the contact pathway) or factor VIIa (of the tissue factor pathway). When activated into factor IXa, it acts by hydrolysing one arginine-isoleucine bond in factor X to form factor Xa. It requires calcium, membrane phospholipids, and factor VIII as cofactors to do so.

Genetics


The gene for factor IX is located on the X chromosome (Xq27.1-q27.2).

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safety of 40k pegyl8d recombinant factor ix in non-bleeding ppl w/ haemophilia b http://bit.ly/7RhqmP
ustrials (US Trials) Fri, 18 Dec 2009 22:50:42 -0000
safety of 40k pegyl8d recombinant factor ix in non-bleeding ppl w/ haemophilia b http://bit.ly/7RhqmP
recombinant factor ix product, ib1001, in ppl w/ hemophilia b http://bit.ly/84AFsi
_clinical_trial (Clinical Trials) Fri, 18 Dec 2009 04:34:50 -0000
recombinant factor ix product, ib1001, in ppl w/ hemophilia b http://bit.ly/84AFsi
recombinant factor ix product, ib1001, in ppl w/ hemophilia b http://bit.ly/84AFsi
goclinicaltrial (Clinical Trials) Fri, 18 Dec 2009 04:34:41 -0000
recombinant factor ix product, ib1001, in ppl w/ hemophilia b http://bit.ly/84AFsi
recombinant factor ix product, ib1001, in ppl w/ hemophilia b http://bit.ly/84AFsi
newtrials_ (New Clinical Trials) Fri, 18 Dec 2009 04:30:47 -0000
recombinant factor ix product, ib1001, in ppl w/ hemophilia b http://bit.ly/84AFsi
hoping that patients will be honest enough to tell if they lack factor VIII and IX before extraction... bad =(
iamliezl (Liezl Mae) Thu, 17 Dec 2009 12:34:41 -0000
hoping that patients will be honest enough to tell if they lack factor VIII and IX before extraction... bad =(
An open clinical study assessing the efficacy and safety of Factor IX Grifols®, a high.. http://bit.ly/8RZJao http://sciencia.org/
Sciencia (Webmaster Sciencia) Wed, 16 Dec 2009 04:20:02 -0000
An open clinical study assessing the efficacy and safety of Factor IX Grifols®, a high.. http://bit.ly/8RZJao http://sciencia.org/

 
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