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Factor IX (or Christmas factor or Christmas-Eve factor) is one of the serine proteases () of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B.

Physiology


Factor IX is inactive unless activated by factor XIa (of the contact pathway) or factor VIIa (of the tissue factor pathway). When activated into factor IXa, it acts by hydrolysing one arginine-isoleucine bond in factor X to form factor Xa. It requires calcium, membrane phospholipids, and factor VIII as cofactors to do so.

Genetics


The gene for factor IX is located on the X chromosome (Xq27.1-q27.2).

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@SkyeCebh: yes indeed .. the mood factor ix always there..!! ♫ http://blip.fm/~fuh9y
beyond_black666 (faran syed) Wed, 04 Nov 2009 09:54:44 -0000
@SkyeCebh: yes indeed .. the mood factor ix always there..!! ♫ http://blip.fm/~fuh9y
BAC and Octapharma Extend Recombinant Factor IX Collaboration for Clinical and Commercial Scale Production: BAC BV a... http://bit.ly/1dNy9h
Bionity_COM (Bionity.COM) Wed, 04 Nov 2009 05:25:03 -0000
BAC and Octapharma Extend Recombinant Factor IX Collaboration for Clinical and Commercial Scale Production: BAC BV a... http://bit.ly/1dNy9h

 
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