.jpg | CAS_number = 33419-42-0 | ATC_prefix = L01 | ATC_suffix = CB01 | ATC_supplemental = | PubChem = 36462 | DrugBank = APRD00239 | chemical_formula = C₂₉H₃₂O₁₃ | molecular_weight = 588.557 g/mol | bioavailability = | protein_bound = 97% | metabolism = | elimination_half-life = oral: 6 h., iv: 6-12 h., iv in children: 3 h. | pregnancy_category = | legal_status = | routes_of_administration = Oral, intravenous | excretion = Renal and faeces }} Etoposide phosphate (Eposin®, Etopophos®, Vepesid®, VP-16®) is an inhibitor of the enzyme topoisomerase II. It is used as a form of chemotherapy for malignancies such as lung cancer, testicular cancer, lymphoma, non-lymphocytic leukemia, and glioblastoma multiforme. It is often given in combination with other drugs.

Chemically it derives from podophyllotoxin, a toxin found in the American Mayapple.

It is given intravenously or by mouth in capsule form. If the drug is given by IV it must be done slowly over a 30 to 60 minute period because it can lower blood pressure as it is being administered. Blood pressure is checked often during infusing. The physician may lengthen or shorten the time depending on circumstances.

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Thank you everyone for your thoughts throughout the night! Just finished the Etoposide, now onto Cisplatin at 6:30 am....thanks again @drew
ommegang (Andrew Gemmell) Fri, 06 Nov 2009 12:00:29 -0000
Thank you everyone for your thoughts throughout the night! Just finished the Etoposide, now onto Cisplatin at 6:30 am....thanks again @drew
Day 2 of Barry's Induction 2 chemotherapy. He is getting cytarabine and etoposide right now.
sean75p (Sean Pham) Tue, 03 Nov 2009 23:02:40 -0000
Day 2 of Barry's Induction 2 chemotherapy. He is getting cytarabine and etoposide right now.

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