.jpg | CAS_number = 33419-42-0 | ATC_prefix = L01 | ATC_suffix = CB01 | ATC_supplemental = | PubChem = 36462 | DrugBank = APRD00239 | chemical_formula = C₂₉H₃₂O₁₃ | molecular_weight = 588.557 g/mol | bioavailability = | protein_bound = 97% | metabolism = | elimination_half-life = oral: 6 h., iv: 6-12 h., iv in children: 3 h. | pregnancy_category = | legal_status = | routes_of_administration = Oral, intravenous | excretion = Renal and faeces }} Etoposide phosphate (Eposin®, Etopophos®, Vepesid®, VP-16®) is an inhibitor of the enzyme topoisomerase II. It is used as a form of chemotherapy for malignancies such as lung cancer, testicular cancer, lymphoma, non-lymphocytic leukemia, and glioblastoma multiforme. It is often given in combination with other drugs.

Chemically it derives from podophyllotoxin, a toxin found in the American Mayapple.

It is given intravenously or by mouth in capsule form. If the drug is given by IV it must be done slowly over a 30 to 60 minute period because it can lower blood pressure as it is being administered. Blood pressure is checked often during infusing. The physician may lengthen or shorten the time depending on circumstances.

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systemic vincristine, carboplatin, & etoposide, subtenon carboplatin, & local ophthalmic thrpy in treating children w/ http://bit.ly/7Pmj2i
recruitingtrial (Recruiting Trials) Mon, 30 Nov 2009 07:32:45 -0000
systemic vincristine, carboplatin, & etoposide, subtenon carboplatin, & local ophthalmic thrpy in treating children w/ http://bit.ly/7Pmj2i
phase i blinostat in combo w/ cisplatin & etoposide in adults w/ small cell lung carcinoma & other advanced cancers http://bit.ly/7IQYnJ
paidtrials (US Clinical Trials) Mon, 30 Nov 2009 07:32:38 -0000
phase i blinostat in combo w/ cisplatin & etoposide in adults w/ small cell lung carcinoma & other advanced cancers http://bit.ly/7IQYnJ
vorinostat, rituximab, ifosfamide, carboplatin, & etoposide in treating ppl w/ relapsed or primary refractory lymphoma http://bit.ly/76f7JA
cancertrials_ (Cancer Trials) Sun, 29 Nov 2009 20:32:41 -0000
vorinostat, rituximab, ifosfamide, carboplatin, & etoposide in treating ppl w/ relapsed or primary refractory lymphoma http://bit.ly/76f7JA
4 hours of Etoposide
lymphomaboy (Lymphoma Boy) Sun, 29 Nov 2009 16:03:36 -0000
4 hours of Etoposide
Etoposide started. 4 hours of this...
lymphomaboy (Lymphoma Boy) Sat, 28 Nov 2009 15:58:48 -0000
Etoposide started. 4 hours of this...
gossypol, cisplatin, & etoposide in treating ppl w/ advanced solid tumors or extensive stage small cell lung cancer http://bit.ly/5y4tYV
cancertrials_ (Cancer Trials) Sat, 28 Nov 2009 13:02:48 -0000
gossypol, cisplatin, & etoposide in treating ppl w/ advanced solid tumors or extensive stage small cell lung cancer http://bit.ly/5y4tYV

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