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Esomeprazole (IPA: ) is a proton pump inhibitor used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and Zollinger-Ellison syndrome. Esomeprazole magnesium trihydrate is marketed by AstraZeneca under the tradename Nexium. Esomeprazole is the S-enantiomer of omeprazole (marketed as Losec/Prilosec), and AstraZeneca claims improved efficacy of this single enantiomer product over the racemic mixture of omeprazole (see below).
Pharmacology
Main article: Proton pump inhibitor
Esomeprazole is a proton pump inhibitor which reduces gastric acid secretion through inhibition of H+/K+-ATPase in gastric parietal cells. By inhibiting the functioning of this enzyme, the drug prevents formation of gastric acid.
More on [ Esomeprazole ]
Esomeprazole - FamilyDoctor.org - Information for consumers in English or Spanish.
Nexium (Esomeprazole) - AstraZeneca - Official Pharmaceutical website intended for consumers with link to site for health professionals.
Meta Description: [ The Purple Pill Nexium (esomeprazole magnesium). Learn about relief from frequent, persistent heartburn due to acid reflux disease or gastroesophageal reflux disease (GERD). Get a 7-day free trial coupon. ]
Nexium for Healthcare Professionals - Provides medication description, full prescribing information and resources for healthcare professionals.
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