Esmolol (tradename Brevibloc®) is a cardioselective beta₁ receptor blocker with rapid onset, a very short duration of action, and no significant intrinsic sympathomimetic or membrane stabilising activity at therapeutic dosages.

Esmolol decreases the force and rate of heart contractions by blocking beta-adrenergic receptors of the sympathetic nervous system, which are found in the heart, lungs and other organs of the body. Esmolol prevents the action of two naturally occurring substances: epinephrine and norepinephrine.

Dosing

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Esmolol is given by slow intravenous injection. It is commonly used in patients during surgery to prevent or treat tachycardia, and is also used in treatment of supraventricular tachycardia.

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comp of eff of intraoperative adminstration of metoprolol or esmolol on general anesthetic requirement http://bit.ly/6RvipF
hearttrials (Heart Trials) Thu, 03 Dec 2009 10:10:50 -0000
comp of eff of intraoperative adminstration of metoprolol or esmolol on general anesthetic requirement http://bit.ly/6RvipF

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