Ergoline is a chemical compound whose structural skeleton is contained in a diverse range of alkaloids and a few psychedelic drugs (ololiuhqui, LSD). Substances derived from ergoline are used clinically for the purpose of vasoconstriction (5-HT 1 Agonists - Ergotamine) and in the treatment of migraine (used with caffeine) and Parkinson's disease, some are implicated in the disease ergotism. Ergometrine and ergotamine are listed as Table I precursors under the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances^*.

Chemistry

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There are three main classes of ergoline derivatives, the water-soluble amides of lysergic acid, the water-insoluble ergopeptide alkaloids, and the clavine group.

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