Desflurane (1,2,2,2-tetrafluoroethyl difluoromethyl ether) is a highly fluorinated methyl ethyl ether used for maintenance of general anaesthesia. Together with sevoflurane, it is gradually replacing isoflurane for human use, except in the third world where its high cost precludes its use. It has the most rapid onset and offset of the volatile anaesthetic drugs used for general anaesthesia due to its low solubility in blood.

The major drawbacks of desflurane are its low potency, its pungency and its high cost. It may cause tachycardia secondary to airway irritability when administered at rapidly increased concentrations greater than 1 MAC.

Though it vaporises very readily, it is a liquid at room temperature. Anaesthetic machines use an unusual anaesthetic vaporiser that heats it to generate a gas.

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What is the best way to conduct low-flow sevoflurane or desflurane anesthesia? http://bit.ly/7XUCBk
gasexchange (gasexchange.com) Tue, 22 Dec 2009 23:18:55 -0000
What is the best way to conduct low-flow sevoflurane or desflurane anesthesia? http://bit.ly/7XUCBk
That plate of tater tots put me down faster than huffing desflurane.
blastcap (Jack Auses) Sat, 19 Dec 2009 20:28:56 -0000
That plate of tater tots put me down faster than huffing desflurane.

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