Dantrolene sodium is a muscle relaxant that is currently the only specific and effective treatment for malignant hyperthermia. It is also used in the management of neuroleptic malignant syndrome, muscle spasticity (e.g. after strokes, in paraplegia, cerebral palsy, or patients with multiple sclerosis) and ecstasy intoxication.

Chemistry

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Chemically it is a hydantoin derivative, but does not exhibit antiepileptic activity like other hydantoin derivates such as phenytoin.

The related substance azumolene is under development for similar indications. It has a bromine residue instead of the nitrite group, and is 30 times more water-soluble.

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Dantrolene Sodium - Twitter Search

Safety of Low-Dose Oral Dantrolene Sodium on Hepatic Function: Archives of Physical Medicine and Rehabilitation http://t.co/BHgSoEY #GI
MDLinx (Sandeep Pulim MD) Mon, 12 Sep 2011 16:17:11 -0000
Safety of Low-Dose Oral Dantrolene Sodium on Hepatic Function: Archives of Physical Medicine and Rehabilitation http://t.co/BHgSoEY #GI
Safety of Low-Dose Oral Dantrolene Sodium on Hepatic Function: Archives of Physical Medicine and Rehabilitation http://t.co/zdZFeSc #neuro
MDLinx (Sandeep Pulim MD) Wed, 07 Sep 2011 18:30:02 -0000
Safety of Low-Dose Oral Dantrolene Sodium on Hepatic Function: Archives of Physical Medicine and Rehabilitation http://t.co/zdZFeSc #neuro
ایرشفا: DANTROLENE SODIUM - دانترولن‌: داروهای ژنریک : Musculoskeletal Drugs ( داروهاي مربوط به عضلات ) داروهای... http://t.co/X2UeyGO
hot_health (hot_health) Tue, 06 Sep 2011 04:57:27 -0000
ایرشفا: DANTROLENE SODIUM - دانترولن‌: داروهای ژنریک : Musculoskeletal Drugs ( داروهاي مربوط به عضلات ) داروهای... http://t.co/X2UeyGO
Introduction of Dantrolene sodium hemiheptahydrate http://t.co/Fu9BuDR
chemicalengr (Chemical Engg) Tue, 06 Sep 2011 04:29:14 -0000
Introduction of Dantrolene sodium hemiheptahydrate http://t.co/Fu9BuDR

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