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Daclizumab (Zenapax) is a murine-human chimaerised monoclonal antibody to the IL-2Rα receptor of T cells. It is used to prevent rejection in organ transplantation, especially in kidney transplants.
It is given in multiple doses, the first 1 hour before the transplant operation and 5 further doses given at two week intervals after the transplant. These saturate the receptors and prevent T cell activation and thus prevent formation of antibodies against the transplant.
Like the similar drug basiliximab, daclizumab reduces the incidence and severity of acute rejection in kidney transplantation without increasing the incidence of opportunistic infections.
More on [ Daclizumab ]
Allergy/Immunology Immunosuppression With Low-Dose Daclizumab in Liver Transplant Recipients .. http://bit.ly/1TBi3k
MDLinx (Sandeep Pulim MD) Fri, 06 Nov 2009 15:08:31 -0000
Allergy/Immunology Immunosuppression With Low-Dose Daclizumab in Liver Transplant Recipients .. http://bit.ly/1TBi3k
Facet expects $30M dev milestone from Biogen for daclizumab in 1H '10. More reason for BIIB to up its $14.50/sh offer? Today: FACT $17.16.
InVivoBlogAlex (Alex Lash) Wed, 04 Nov 2009 22:32:49 -0000
Facet expects $30M dev milestone from Biogen for daclizumab in 1H '10. More reason for BIIB to up its $14.50/sh offer? Today: FACT $17.16.
Peds: Extended daclizumab monotherapy for rejection-free survival in non-adherent adolescent recipients of renal allogra http://url4.eu/hD6t
MDLinx (Sandeep Pulim MD) Wed, 04 Nov 2009 09:51:27 -0000
Peds: Extended daclizumab monotherapy for rejection-free survival in non-adherent adolescent recipients of renal allogra http://url4.eu/hD6t
Zenapax ( Daclizumab ) By Roche - Official pharmaceutical manufacturer's site with full prescribing information and information on patient assistance programs.
