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Daclizumab (Zenapax) is a murine-human chimaerised monoclonal antibody to the IL-2Rα receptor of T cells. It is used to prevent rejection in organ transplantation, especially in kidney transplants.
It is given in multiple doses, the first 1 hour before the transplant operation and 5 further doses given at two week intervals after the transplant. These saturate the receptors and prevent T cell activation and thus prevent formation of antibodies against the transplant.
Like the similar drug basiliximab, daclizumab reduces the incidence and severity of acute rejection in kidney transplantation without increasing the incidence of opportunistic infections.
More on [ Daclizumab ]
MPR News: Roche discontinues Zenapax injection: Roche has announced that it has discontinued Zenapax (daclizumab st... http://bit.ly/7ClWtZ
eMPR (MPR) Tue, 22 Dec 2009 18:02:54 -0000
MPR News: Roche discontinues Zenapax injection: Roche has announced that it has discontinued Zenapax (daclizumab st... http://bit.ly/7ClWtZ
infliximab, sirolimus & daclizumab 2 treat age-rel8d macular degeneration http://bit.ly/5ZLIIS
localtrials (US Clinical Trials ) Fri, 18 Dec 2009 09:54:42 -0000
infliximab, sirolimus & daclizumab 2 treat age-rel8d macular degeneration http://bit.ly/5ZLIIS
infliximab, sirolimus & daclizumab 2 treat age-rel8d macular degeneration http://bit.ly/5ZLIIS
usclinicaltrial (US Clinical Trials) Fri, 18 Dec 2009 09:34:48 -0000
infliximab, sirolimus & daclizumab 2 treat age-rel8d macular degeneration http://bit.ly/5ZLIIS
infliximab, sirolimus & daclizumab 2 treat age-rel8d macular degeneration http://bit.ly/5ZLIIS
recruitingtrial (Recruiting Trials) Fri, 18 Dec 2009 08:54:49 -0000
infliximab, sirolimus & daclizumab 2 treat age-rel8d macular degeneration http://bit.ly/5ZLIIS
stdy 2 determine whether thrpy w/ daclizumab will bnefit ppl w/ bone marrow failure http://bit.ly/7Xwymi
goclinicaltrial (Clinical Trials) Thu, 17 Dec 2009 22:42:50 -0000
stdy 2 determine whether thrpy w/ daclizumab will bnefit ppl w/ bone marrow failure http://bit.ly/7Xwymi
stdy 2 determine whether thrpy w/ daclizumab will bnefit ppl w/ bone marrow failure http://bit.ly/7Xwymi
newtrials_ (New Clinical Trials) Thu, 17 Dec 2009 22:38:50 -0000
stdy 2 determine whether thrpy w/ daclizumab will bnefit ppl w/ bone marrow failure http://bit.ly/7Xwymi
Zenapax ( Daclizumab ) By Roche - Official pharmaceutical manufacturer's site with full prescribing information and information on patient assistance programs.
