Estradiol (17β-estradiol) (also oestradiol) is a sex hormone. Labelled the "female" hormone but also present in males it represents the major estrogen in humans. Estradiol has not only a critical impact on reproductive and sexual functioning, but also affects other organs including bone structure.
Estradiol, like other sex steroids, is derived from cholesterol. After side chain cleavage and utilizing the delta-5 pathway or the delta-4 pathway androstenedione is the key intermediary. Androstendione is either converted to testosterone which in turn undergoes aromatization to estradiol, or, alternatively, androstendione is aromatized to estrone which is converted to estradiol.

Diane-35 - Cyproterone acetate and ethinyl estradiol. Combined acne treatment and oral contraceptive. Features information about the pill, FAQs, and tips.
Meta Description: [ Femalelife is your online resource on contraception, sexuality, menstruation, the pill, and family planing! Check out which contraceptive suits you best! ]
Dianette - Features information about the use of this drug in the treatment of hirsutism and polycystic ovarian syndrome.
Dianette - Product information from Schering in PDF format. [Acrobat Reader required]
Disclosure: Two-for-One - CBC news program explores the use of the drug as an oral contraceptive despite it never having been approved for that use in Canada.
Meta Description: [ Thousands of Canadian women are taking a drug, Diane-35, for a use that Health Canada says they shouldn't. CBC News: Disclosure discovers why it's happening and what patients are not being told before they are prescribed the drug. ]
| Higher Estrogen Exposure with Ortho Evra Patch (Apr. 2008) | |
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