Cyclophosphamide is a nitrogen mustard alkylating agent, used to treat various types of cancer and some autoimmune disorders. It is a "prodrug"; it is converted in the liver to active forms that have chemotherapeutic activity.

Uses

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The main use of cyclophosphamide is together with other chemotherapy agents in the treatment of lymphomas, some forms of leukemia and some solid tumors.

In addition, its use is becoming more common in autoimmune diseases where disease-modifying antirheumatic drugs (DMARDs) have been ineffective. Systemic lupus erythematosus (SLE) with severe lupus nephritis, for example, may respond to pulsed cyclophosphamide.

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Cyclophosphamide as second-line therapy in multiple sclerosis: benefits and risks: Abstract  Cyclopho.. http://bit.ly/3lXlBo
rootaq (R. Adam Quigley) Thu, 05 Nov 2009 21:11:03 -0000
Cyclophosphamide as second-line therapy in multiple sclerosis: benefits and risks: Abstract  Cyclopho.. http://bit.ly/3lXlBo
Radiology publications: Fluorouracil, Epirubicin, and Cyclophosphamide With Either Docetaxe... http://bit.ly/1Xq8F2
Radiology_help (Radiology help) Thu, 05 Nov 2009 19:49:51 -0000
Radiology publications: Fluorouracil, Epirubicin, and Cyclophosphamide With Either Docetaxe... http://bit.ly/1Xq8F2
Rheum: Mycophenolate mofetil and intravenous cyclophosphamide are similar as induction therapy for class V lupus nephrit http://url4.eu/hO4B
MDLinx (Sandeep Pulim MD) Thu, 05 Nov 2009 12:24:50 -0000
Rheum: Mycophenolate mofetil and intravenous cyclophosphamide are similar as induction therapy for class V lupus nephrit http://url4.eu/hO4B
Heme/Onc: Fluorouracil, epirubicin, and cyclophosphamide with either docetaxel or vinorelbine, with or without trastuzum http://url4.eu/hNxB
MDLinx (Sandeep Pulim MD) Thu, 05 Nov 2009 12:23:57 -0000
Heme/Onc: Fluorouracil, epirubicin, and cyclophosphamide with either docetaxel or vinorelbine, with or without trastuzum http://url4.eu/hNxB
Doxorubicin and Cyclophosphamide in Treating Older Women With Stage I, Stage II, or Stage III Breast Cancer http://bit.ly/28UdRe
trialscentral (Trials Central) Wed, 04 Nov 2009 19:33:43 -0000
Doxorubicin and Cyclophosphamide in Treating Older Women With Stage I, Stage II, or Stage III Breast Cancer http://bit.ly/28UdRe
Heme/Onc: Phase 1/2 study of lumiliximab combined with fludarabine, cyclophosphamide, and rituximab in patients with rel http://url4.eu/hCgY
MDLinx (Sandeep Pulim MD) Wed, 04 Nov 2009 09:22:05 -0000
Heme/Onc: Phase 1/2 study of lumiliximab combined with fludarabine, cyclophosphamide, and rituximab in patients with rel http://url4.eu/hCgY

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