Cyclobenzaprine is a skeletal muscle relaxant and a central nervous system (CNS) depressant. It is marketed as Flexeril (5 and 10 mg tablets). Both the 5 and 10 milligram tablets are available generically.

Mechanism of action

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The exact mechanism of action for cyclobenzaprine is unknown. Current research appears to indicate that cyclobenzaprine acts on the locus coeruleus where it results in increased norepinephrine release, potentially through the gamma fibers which innervate and inhibit the alpha motor neurons in the vetral horn of the spinal cord.^* Decreased firing of the alpha motor neuron results in decreased muscular tone.

Indications

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Cyclobenzaprine is typically prescribed to relieve pain and muscle spasms. Typically, muscle spasms occur in an injury to stabilize the affected body part and prevent further damage. The spasm of the muscles can actually increase the pain level. It is believed that by decreasing muscular spasm, pain is diminished. A common application would be that of a whiplash injury in a car accident.

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7% of cyclobenzaprine users get SIGNIFICANT side-effects: http://tinyurl.com/ykn4vbq
iGuard (iGUARD.org) Sun, 08 Nov 2009 02:17:03 -0000
7% of cyclobenzaprine users get SIGNIFICANT side-effects: http://tinyurl.com/ykn4vbq
pills popped! off to a better place... thanks Cyclobenzaprine!
emoney_ (E Money) Fri, 06 Nov 2009 22:34:42 -0000
pills popped! off to a better place... thanks Cyclobenzaprine!
Latest Topics: Septrum, extacy, EBB, intagesic mr, Hydrocodone, round l p z purple oval pill with k, watson 349, cyclobenzaprine, neurobion
druginfo (Medicine Community) Fri, 06 Nov 2009 08:30:07 -0000
Latest Topics: Septrum, extacy, EBB, intagesic mr, Hydrocodone, round l p z purple oval pill with k, watson 349, cyclobenzaprine, neurobion
The doctor gave me cyclobenzaprine......for my neck, but I feel it all over!
NailedByAmber (Amber Stores) Fri, 06 Nov 2009 03:50:10 -0000
The doctor gave me cyclobenzaprine......for my neck, but I feel it all over!
Ugh. The morning after a muscle relaxant. Did you know cyclobenzaprine is an over-the-counter med in other countries?
CarlCravens (Carl Cravens) Wed, 04 Nov 2009 14:11:48 -0000
Ugh. The morning after a muscle relaxant. Did you know cyclobenzaprine is an over-the-counter med in other countries?
Just left work early....not feelin too good again....ji hurtin....cyclobenzaprine and ibuprofen #ondeck
iamEmoney (E'money) Mon, 02 Nov 2009 16:00:14 -0000
Just left work early....not feelin too good again....ji hurtin....cyclobenzaprine and ibuprofen #ondeck

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