Cyclobenzaprine is a skeletal muscle relaxant and a central nervous system (CNS) depressant. It is marketed as Flexeril (5 and 10 mg tablets). Both the 5 and 10 milligram tablets are available generically.

Mechanism of action

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The exact mechanism of action for cyclobenzaprine is unknown. Current research appears to indicate that cyclobenzaprine acts on the locus coeruleus where it results in increased norepinephrine release, potentially through the gamma fibers which innervate and inhibit the alpha motor neurons in the vetral horn of the spinal cord.^* Decreased firing of the alpha motor neuron results in decreased muscular tone.

Indications

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Cyclobenzaprine is typically prescribed to relieve pain and muscle spasms. Typically, muscle spasms occur in an injury to stabilize the affected body part and prevent further damage. The spasm of the muscles can actually increase the pain level. It is believed that by decreasing muscular spasm, pain is diminished. A common application would be that of a whiplash injury in a car accident.

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Interactions of Prednisone, Cyclobenzaprine Hydrochloride for a female aged 35 who has Colitis by eHealthMe http://bit.ly/7skwFa
drugsideeffects (drug side effects) Sat, 02 Jan 2010 00:18:18 -0000
Interactions of Prednisone, Cyclobenzaprine Hydrochloride for a female aged 35 who has Colitis by eHealthMe http://bit.ly/7skwFa
Cyclobenzaprine + Diet Mountain Dew FTW (perhaps?)
kylelady (Kyle Lady) Fri, 01 Jan 2010 18:58:24 -0000
Cyclobenzaprine + Diet Mountain Dew FTW (perhaps?)
Interactions of Escitalopram, Cyclobenzaprine Hydrochloride for a female aged 49 who has Anxiety by eHealthMe http://bit.ly/7eOfO3
druginteraction (drug interactions) Fri, 01 Jan 2010 0 Subscribe to Cyclobenzaprine RSS feed