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Co-trimoxazole (abbreviated SXT, TMP-SMX, or TMP-sulfa) is an antibiotic combination of trimethoprim and sulfamethoxazole, in the ratio of 1 to 5, used in the treatment of a variety of bacterial infections. The name co-trimoxazole is the British Approved Name, and has been marketed worldwide under many trade names including Septrin (GSK), Bactrim (Roche), and various generic preparations. According to the American Hospital Formulary Service, "co-trimoxazole usually is bactericidal." Other sources list this antibiotic as bacteriostatic.
Synergistic action
Co-trimoxazole exhibits a synergistic antibacterial effect when compared to each of its components administered singly. This is because trimethoprim and sulfamethoxazole inhibit successive steps in the folate synthesis pathway (see diagram below).
More on [ Co-trimoxazole ]
Antibiotics :: Drugs and Medications
Cotrimoxazole http://tinyurl.com/ydl9znl
bisex101 (BISEX101 BiSex 101) Wed, 23 Dec 2009 15:24:49 -0000
Cotrimoxazole http://tinyurl.com/ydl9znl
Iyah fit :(, trimethoprim dan sulfamethoxazole kan yaa? hehe RT @fitriazizah: km sakit shooof? Hayo cotrimoxazole isinya
shofiursila (shoffy ursila b) Sun, 20 Dec 2009 03:04:20 -0000
Iyah fit :(, trimethoprim dan sulfamethoxazole kan yaa? hehe RT @fitriazizah: km sakit shooof? Hayo cotrimoxazole isinya
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gregdick (Greg Dick) Fri, 18 Dec 2009 02:46:40 -0000
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DrugDigest: Cotrimoxazole - Information on dosage, usage, side effects, interactions, and drug comparisons, including generics when available. Sold under brand names sush as: Bactrim, Cotrim, Septra, and Sulfatrim.
TMP-SMX (Bactrim) - Trimethoprim-Sulfamethoxazole, TMP-SMX, Septra.
