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Colchicine is a highly poisonous alkaloid, originally extracted from plants of the genus Colchicum (Autumn crocus, also known as the "Meadow saffron"). Originally used to treat rheumatic complaints and especially gout, it was also prescribed for its cathartic and emetic effects. Its present use is mainly in the treatment of gout.

History


Colchicum extract was first described as a treatment for gout in De Materia Medica by Padanius Dioscorides in the first century CE.

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MedlinePlus: Colchicine Oral - Provides information on usage, precautions, side effects and brand names when available. Data provided by various government agencies and health-related organizations.
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