Clonazepam (marketed by Roche under the trade-name Klonopin® in the United States and Rivotril® in Europe, South America and Canada) is a drug which is a benzodiazepine derivative. It is a highly potent anticonvulsant, amnestic and anxiolytic.
Pharmacology
Like other benzodiazepines, clonazepam is believed to act by simulating the action of GABA on the central nervous system. Because of strong anxiolytic properties and euphoric side-effects it is said to be among the class of 'highly potent' benzodiazepines with a higher risk of abuse, misuse and dependence than other benzodiazepines, excluding alprazolam which alone is considered to be the most potent. The sedative effects of clonazepam are relatively weak, compared to its strong anxiolytic and anticonvulsant effects. One quarter of a milligram (0.25mg) of clonazepam is approximately equivalent to five milligrams (5.00mg) of diazepam.
Tourette Syndrome - Clonazepam has shown to be helpful in reducing and dealing with the physical motor tics associated with TS, though is still considered an off-label usage by many.
The Klonopin Discussion - An interactive forum for discussion of clonazepam, brand name Klonopin. Also includes confirmed factual information.
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