Gourt > Health > Pharmacy > Drugs and Medications > C > Cladribine
.png | width = 161 | CAS_number = 4291-63-8 | ATC_prefix = L01 | ATC_suffix = BB04 | ATC_supplemental = | PubChem = 20279 | DrugBank = APRD00260 | chemical_formula = C10H12ClN5O3 | molecular_weight = 285.687 g/mol | bioavailability = | protein_bound = 20% | metabolism = | elimination_half-life = 5.4 hours | pregnancy_category = | legal_status = | routes_of_administration = }} Cladribine is a drug commonly used to treat hairy cell leukemia (leukemic reticuloendotheliosis). Its brand name is Leustatin, and it is commonly referred to as 2CDA.
A purine analog, it is a synthetic antineoplastic agent with immunosuppressive effects. Chemically, it mimics the nucleoside adenosine and thus inhibits the enzyme adenosine deaminase, which interferes with the cell's ability to process DNA. It is easily destroyed by normal cells in the body except for blood cells, with the result that it produces relatively few side effects and results in very little non-target cell loss.
Side Effects
About half of patients have no significant side effects from this treatment. More on [ Cladribine ]
prospective observational long-term safety registry of multiple sclerosis ppl who have particip8d in cladribine http://bit.ly/4EQ24v
_clinical_trial (Clinical Trials) Sat, 19 Dec 2009 04:50:54 -0000
prospective observational long-term safety registry of multiple sclerosis ppl who have particip8d in cladribine http://bit.ly/4EQ24v
prospective observational long-term safety registry of multiple sclerosis ppl who have particip8d in cladribine http://bit.ly/4EQ24v
ustrials (US Trials) Sat, 19 Dec 2009 04:43:05 -0000
prospective observational long-term safety registry of multiple sclerosis ppl who have particip8d in cladribine http://bit.ly/4EQ24v
prospective observational long-term safety registry of multiple sclerosis ppl who have particip8d in cladribine http://bit.ly/4EQ24v
goclinicaltrial (Clinical Trials) Sat, 19 Dec 2009 04:34:45 -0000
prospective observational long-term safety registry of multiple sclerosis ppl who have particip8d in cladribine http://bit.ly/4EQ24v
prospective observational long-term safety registry of multiple sclerosis ppl who have particip8d in cladribine http://bit.ly/4EQ24v
newtrials_ (New Clinical Trials) Sat, 19 Dec 2009 04:18:41 -0000
prospective observational long-term safety registry of multiple sclerosis ppl who have particip8d in cladribine http://bit.ly/4EQ24v
