Ciprofloxacin is the generic international name for the synthetic antibiotic manufactured and sold by Bayer Pharmaceutical under the brand names Cipro® and Ciproxin® (and other brand names in other markets, e.g. veterinary drugs), belonging to a group called fluoroquinolones. Ciprofloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase, which allows the untwisting required to replicate one DNA double helix into two.

Activity

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Ciprofloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria.

• Enterobacteriaceae
• Vibrio
• Haemophilus influenzae
• Neisseria gonorrhoeae
• Neisseria menigitidis
• Moraxella catarrhalis
• Brucella
• Campylobacter
• Mycobacterium intracellulare
• Legionella sp.
• Pseudomonas aeruginosa
• Bacillus anthracis - that causes anthrax

Weak activity against:

• Streptococcus pneumoniae
• Chlamydia trachomatis
• Chlamydia pneumoniae

More on [ Ciprofloxacin ]

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