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Busulfan is a chemotherapy drug that is an alkylating agent (slows the growth of cancer cells). It is marketed in the US by GlaxoSmithKline under the brand name Myleran, and has been in clinical use since 1959. Currently, its main uses are in bone marrow transplantation, especially in Chronic myelogenous leukemia (CML), where it is used as a conditioning drug. Toxicity may include pulmonary fibrosis and hyperpigmentation.

Busulfan also induces thrombocytopenia, a condition of lowered blood platelet count and activity. The drug was recently used in a study (published April 2006, Science) to examine the role of platelet-transported serotonin in liver regeneration.

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fludarabine & busulfan followed by allogeneic stem cell transplant in treating older ppl w/ acute myeloid leukemia in http://bit.ly/8g3yoX
newtrials_ (New Clinical Trials) Sat, 02 Jan 2010 04:30:18 -0000
fludarabine & busulfan followed by allogeneic stem cell transplant in treating older ppl w/ acute myeloid leukemia in http://bit.ly/8g3yoX
fludarabine & busulfan followed by allogeneic stem cell transplant in treating older ppl w/ acute myeloid leukemia in http://bit.ly/8g3yoX
_clinical_trial (Clinical Trials) Sat, 02 Jan 2010 04:22:28 -0000
fludarabine & busulfan followed by allogeneic stem cell transplant in treating older ppl w/ acute myeloid leukemia in http://bit.ly/8g3yoX
fludarabine & busulfan followed by allogeneic stem cell transplant in treating older ppl w/ acute myeloid leukemia in http://bit.ly/8g3yoX
recruitingtrial (Recruiting Trials) Sat, 02 Jan 2010 04:22:26 -0000
fludarabine & busulfan followed by allogeneic stem cell transplant in treating older ppl w/ acute myeloid leukemia in http://bit.ly/8g3yoX
fludarabine & busulfan followed by allogeneic stem cell transplant in treating older ppl w/ acute myeloid leukemia in http://bit.ly/8g3yoX
localtrials (US Clinical Trials ) Sat, 02 Jan 2010 04:22:25 -0000
fludarabine & busulfan followed by allogeneic stem cell transplant in treating older ppl w/ acute myeloid leukemia in http://bit.ly/8g3yoX
fludarabine & busulfan followed by allogeneic stem cell transplant in treating older ppl w/ acute myeloid leukemia in http://bit.ly/8g3yoX
goclinicaltrial (Clinical Trials) Sat, 02 Jan 2010 04:22:18 -0000
fludarabine & busulfan followed by allogeneic stem cell transplant in treating older ppl w/ acute myeloid leukemia in http://bit.ly/8g3yoX
fludarabine & busulfan followed by allogeneic stem cell transplant in treating older ppl w/ acute myeloid leukemia in http://bit.ly/8g3yoX
ustrials (US Trials) Sat, 02 Jan 2010 04:18:27 -0000
fludarabine & busulfan followed by allogeneic stem cell transplant in treating older ppl w/ acute myeloid leukemia in http://bit.ly/8g3yoX

 
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MedlinePlus: Busulfan - Provides information on usage, precautions, side effects and brand names when available. Data provided by government agencies and health-related organizations.
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