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Buprenorphine, also colloquially referred to as bupe, is an opioid drug with partial agonist and antagonist actions. Buprenorphine hydrochloride was first marketed in the 1980s by Reckitt & Colman (now Reckitt Benckiser) as an analgesic, yet is now primarily used for the treatment of opioid addiction. It is a Schedule III drug under the Convention on Psychotropic Substances*.
Commercial preparations
British firm Reckitt & Colman (now Reckitt Benckiser) first marketed buprenorphine under the trade names Temgesic (sublingual/parenteral preparations, no active additives) and Buprenex (parenteral, no active additives). Two more recent formulations from Reckitt Benckiser have been approved for opioid addiction treatment in the U.S.: Subutex (flavorless sublingual, no active additives; in 2mg and 8mg dosages) and Suboxone (orange-tang flavored sublingual, one part naloxone for every four parts buprenorphine; hexagon shaped tablet in 2mg and 8mg dosages). Suboxone contains the opioid antagonist naloxone to deter illicit intravenous preparation of the tablet, this is intended to attenuate the effects of buprenorphine on opioid-naive users should this formulation be injected - however no human studies have been done demonstrating the efficacy of this approach with buprenorphine and a growing number of street reports indicate that the naloxone is ineffective. It must also be noted that buprenorphine in and of itself will induce a precipitated withdrawal syndrome if ingested by an acutely opioid dependent individual via any route.
Buprenorphine is also delivered transdermally in 25, 50 and 75 mcg/hour. The trade name in the UK is Transtec, and manufactured by Napp. A new 5, 10 and 20 mcg/hour patch marketed as Bu'7rans (Bu-trans), where the 7 indicates its once weekly dosage for pain in osteoarthritis.
More on [ Buprenorphine ]
Amparafaravola : Drugs: contact for the below drugs: Buprenorphine Butorphanol Diamorphine... http://t.co/3Y3dJ1xR #kerawa
kerawa (kerawa) Mon, 09 Jan 2012 00:39:17 -0000
Amparafaravola : Drugs: contact for the below drugs: Buprenorphine Butorphanol Diamorphine... http://t.co/3Y3dJ1xR #kerawa
Top Posts of 2011 #2 â Dawn Farmâs Position on Buprenorphine Maintenance http://t.co/DUtz4FPE
ThePinckneyCoal (ThePinckneyCoalition) Sun, 08 Jan 2012 21:36:25 -0000
Top Posts of 2011 #2 – Dawn Farm’s Position on Buprenorphine Maintenance http://t.co/DUtz4FPE
Bunex (Buprenorphine) 0.2mg by Safe-Pharma x 1 Strip - Clinx Plus: http://t.co/93YHZdwS via @AddThis
ZaidSaleem313 (zaidsaleem) Sun, 08 Jan 2012 20:41:31 -0000
Bunex (Buprenorphine) 0.2mg by Safe-Pharma x 1 Strip - Clinx Plus: http://t.co/93YHZdwS via @AddThis
Top Posts of 2011 #2 â Dawn Farm's Position on Buprenorphine ...
emelysarmienh (Emely Sarmiento) Sun, 08 Jan 2012 18:27:29 -0000
Top Posts of 2011 #2 – Dawn Farm's Position on Buprenorphine ...
Top Posts of 2011 #2 - Dawn Farmâs Position on Buprenorphine Maintenance http://t.co/EwuZSkOn
dawnfarm (Dawn Farm) Sun, 08 Jan 2012 14:34:30 -0000
Top Posts of 2011 #2 - Dawn Farm’s Position on Buprenorphine Maintenance http://t.co/EwuZSkOn
U.S. Retail Distribution of Buprenorphine Approaches 1.5 Million Grams - NewRelevant http://t.co/3860krBa
IntegratedTrtmt (Addiction Treatment) Sun, 08 Jan 2012 14:00:24 -0000
U.S. Retail Distribution of Buprenorphine Approaches 1.5 Million Grams - NewRelevant http://t.co/3860krBa
MedlinePlus: Buprenorphine Sublingual and Buprenorphine and Naloxone Sublingual - Provides information on usage, precautions, side effects and brand names when available. Data provided by government agencies and health-related organizations.
Meta Description: [ Buprenorphine Sublingual and Buprenorphine and Naloxone Sublingual ]
Suboxone / Subutex - Information for healthcare professionals and patients.
Meta Description: [ Information about SUBOXONE, an office based treatment for opioid dependence. ]
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