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Bosentan is a dual endothelin receptor antagonist important in the treatment of pulmonary artery hypertension (PAH). It's trade name is Tracleer®, which is an oral medication licensed in the U.S., European Union and other countries for the management of PAH. The license holder is Actelion Pharmaceuticals.

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Bosentan Therapy for Pulmonary Arterial Hypertension - Actelion's slide show presentation to the FDA.

FDA Approves First Oral Medication for Pulmonary Arterial Hypertension - Describes the trial results and subsequent approval of Tracleer.
Meta Description: [ FDA Approves First Oral Medication for Pulmonary Arterial Hypertension ]

MedlinePlus: Bosentan - Provides information on usage, precautions, side effects and brand names when available. Data provided by government agencies and health-related organizations
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Tracleer - Features an overview of pulmonary hypertension, prescribing information for US residents, and press releases.

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Importance of Monitoring Liver Function with Tracleer
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