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Bleomycin is a glycosylated linear nonribosomal peptide antibiotic produced by the bacterium Streptomyces verticillus. Bleomycin refers to a family of structurally related compounds. When used as an anti-cancer agent, the chemotherapeutical forms are primarily bleomycin A2 and B2. Bleomycin A2 is shown in the image. The drug is used in the treatment of lymphomas (especially Hodgkin's disease), squamous cell carcinomas, and testicular cancer as well as pleurodesis.
History
Bleomycin was first discovered in 1962 when the Japanese scientist Hamao Umezawa found anti-cancer activity while screening culture filtrates of S. verticullus. Umezawa published his discovery in 1966. The drug was launched in Japan by Nippon Kayaku in 1969. In the US bleomycin gained Food and Drug Administration (FDA) approval in July 1973. It was initially marketed in the US by the Bristol-Myers Squibb precursor Bristol Laboratories under the brand name Blenoxane.
Suppliers
Bristol-Myers Squibb still supplies Blenoxane. There are also generic versions of bleomycin available from Bedford, Sicor and Mayne Pharma. More on [ Bleomycin ]
Bone Marrow Stem Cells Expressing Keratinocyte Growth Factor via an Inducible Lentivirus Protects against Bleomycin... http://bit.ly/5BJH1h
TestCellBio (Test) Tue, 24 Nov 2009 06:26:12 -0000
Bone Marrow Stem Cells Expressing Keratinocyte Growth Factor via an Inducible Lentivirus Protects against Bleomycin... http://bit.ly/5BJH1h
avastin + adriamycin, bleomycin, vinblastine & dacarbazine 4 advanced stage hodgkin lymphoma http://bit.ly/6JQJSo
lymphomatrial (localclinicaltrials) Mon, 23 Nov 2009 19:18:32 -0000
avastin + adriamycin, bleomycin, vinblastine & dacarbazine 4 advanced stage hodgkin lymphoma http://bit.ly/6JQJSo
shares Bleomycin treatment earlier today marked the end of my 4th chemo cycle. ;) Two weeks to rest til the 5t... http://plurk.com/p/2qfbcq
vanessaestor (Vanessa) Mon, 23 Nov 2009 15:48:50 -0000
shares Bleomycin treatment earlier today marked the end of my 4th chemo cycle. ;) Two weeks to rest til the 5t... http://plurk.com/p/2qfbcq
avastin + adriamycin, bleomycin, vinblastine & dacarbazine 4 advanced stage hodgkin lymphoma http://bit.ly/505WT5
bostontrials (Boston Trials) Mon, 23 Nov 2009 11:33:14 -0000
avastin + adriamycin, bleomycin, vinblastine & dacarbazine 4 advanced stage hodgkin lymphoma http://bit.ly/505WT5
avastin + adriamycin, bleomycin, vinblastine & dacarbazine 4 advanced stage hodgkin lymphoma http://bit.ly/7s5lyp
hodgkintrials (hodgkin trials) Mon, 23 Nov 2009 09:25:46 -0000
avastin + adriamycin, bleomycin, vinblastine & dacarbazine 4 advanced stage hodgkin lymphoma http://bit.ly/7s5lyp
headed home today, think I am stopping for my Bleomycin treatment on my way home, and to get Star Trek on Blu Ray and Assasins Creed 2
ommegang (Andrew Gemmell) Tue, 17 Nov 2009 14:24:23 -0000
headed home today, think I am stopping for my Bleomycin treatment on my way home, and to get Star Trek on Blu Ray and Assasins Creed 2
Bleomycin - Information from DrugDigest on dosage, usage, side effects, interactions, and drug comparisons including generics when available.
MedlinePlus: Bleomycin - Provides information on usage, precautions, side effects and brand names when available. Data provided by government agencies and health-related organizations
Meta Description: [ Bleomycin ]
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