Baclofen (brand names Kemstro® and Lioresal®) is a derivative of gamma-aminobutyric acid, and is an agonist specific to mammalian but not fruit fly (Drosophila) GABAB receptors**. It is used for the treatment of spastic movement, especially in instances of spinal cord injury and in multiple sclerosis. Its beneficial effects result from actions at spinal and supraspinal sites. Baclofen can also be used to treat hiccups.
Description of compound
Baclofen is a white to off-white, odorless or practically odorless
crystalline powder, with a
molecular weight of 213.66 g/mol. It is slightly
soluble in water, very slightly soluble in
methanol, and insoluble in
chloroform.
Routes of administration
Baclofen can be administered either orally or
intrathecally (directly into the spinal fluid). Intrathecal administration is often indicated in spasticity patients, as very little of the oral dose actually reaches the spinal fluid.
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Baclofen - Twitter SearchSide Effects and Adverse Reactions to Baclofen - Page 36 - My Way... http://tinyurl.com/ybjjp8ykristmdm (Kristen Malone) Sun, 08 Nov 2009 01:34:41 -0000
Side Effects and Adverse Reactions to Baclofen - Page 36 - My Way... http://tinyurl.com/ybjjp8y
What is baclofen?RandomWisdom (Random Wisdom) Sat, 07 Nov 2009 03:03:08 -0000
What is baclofen?
@ForeverCaroline My post-surgery pain was muscle spasms. They had to pull the big dog drugs to address it. Soma, valium. then baclofenLARRYKLO (Larry Kloefkorn) Fri, 06 Nov 2009 19:59:42 -0000
@ForeverCaroline My post-surgery pain was muscle spasms. They had to pull the big dog drugs to address it. Soma, valium. then baclofen
@paranormalteam I don't get enough excercise.Hope is the baclofen will help w/ pain,then I will feel like getting more excercise.Baby steps!stjulia (Julia St.Amant) Tue, 03 Nov 2009 20:22:44 -0000
@paranormalteam I don't get enough excercise.Hope is the baclofen will help w/ pain,then I will feel like getting more excercise.Baby steps!
@yoclutso mostly it's comb of "shooting" pain and spasms that wake me. more baclofen, maybe.The_Castafiore (Bianca Castafiore) Tue, 03 Nov 2009 19:13:27 -0000
@yoclutso mostly it's comb of "shooting" pain and spasms that wake me. more baclofen, maybe.
Wondermiddel tegen Alcohol Verslaving : Baclofen http://madbello.nl/?p=7256varkens_griep (Varkensgriep) Tue, 03 Nov 2009 19:05:26 -0000
Wondermiddel tegen Alcohol Verslaving : Baclofen http://madbello.nl/?p=7256
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ITB Therapy - Learn about the Intrathecal Baclofen Pump, an implantable therapy to treat severe spasticity caused by multiple sclerosis, cerebral palsy, stroke, and other conditions.
Meta Description: [ Information about Medtronic Intrathecal Baclofen (ITB TM) Therapy for Severe Spasticity ]
MedlinePlus: Baclofen Oral - Provides information about dosage, usage, warnings, and side effects.
Meta Description: [ Baclofen Oral ]