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Aspirin or acetylsalicylic acid (acetosal) is a drug in the family of salicylates, often used as an analgesic (against minor pains and aches), antipyretic (against fever), and anti-inflammatory. It has also an anticoagulant ("blood-thinning") effect and is used in long-term low-doses to prevent heart attacks.

Low-dose long-term aspirin irreversibly blocks formation of thromboxane A2 in platelets, producing an inhibitory effect on platelet aggregation, and this blood-thinning property makes it useful for reducing the incidence of heart attacks. Aspirin produced for this purpose often comes in 75 or 81 mg dispersible tablets and is sometimes called “Junior aspirin”. High doses of aspirin are also given immediately after an acute heart attack. These doses may also inhibit the synthesis of prothrombin and may therefore produce a second and different anticoagulant effect.

Several hundred fatal overdoses of aspirin occur annually, but the vast majority of its uses are beneficial. Its primary undesirable side effects, especially in stronger doses, are gastrointestinal distress (including ulcers and stomach bleeding) and tinnitus. Another side effect, due to its anticoagulant properties, is increased bleeding in menstruating women. Because there appears to be a connection between aspirin and Reye's syndrome, aspirin is no longer used to control flu-like symptoms in minors.

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Analgesics and Anti Inflammatories :: Drugs and Medications

 
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CFDA: FDA Latest Computer Systems Warning Letters

WL Issued to Amrex Zetron Inc
FDA Tue, 14 Apr 2009 00:00:00 -0400
FDA Warning Letter Issued to Amrex Zetron Inc on 14 Apr 2009 by Los Angeles District Office
WL Issued to Coast Institutional Review Board
FDA Tue, 14 Apr 2009 00:00:00 -0400
FDA Warning Letter Issued to Coast Institutional Review Board on 14 Apr 2009 by Center for Drug Evaluation and Research
WL Issued to Branitz, Bruce, MD
FDA Thu, 09 Apr 2009 00:00:00 -0400
FDA Warning Letter Issued to Branitz, Bruce, MD on 09 Apr 2009 by Center for Drug Evaluation and Research
WL Issued to Cote, Charles J., MD
FDA Mon, 02 Mar 2009 00:00:00 -0400
FDA Warning Letter Issued to Cote, Charles J., MD on 02 Mar 2009 by Center for Drug Evaluation and Research
WL Issued to Genzyme Corporation
FDA Fri, 27 Feb 2009 00:00:00 -0400
FDA Warning Letter Issued to Genzyme Corporation on 27 Feb 2009 by New England District Office
WL Issued to Hammill Manufacturing Company
FDA Tue, 06 Jan 2009 00:00:00 -0400
FDA Warning Letter Issued to Hammill Manufacturing Company on 06 Jan 2009 by Cincinnati District Office

CFDA: FDA Latest Drug GCP Warning Letters

WL Issued to Coast Institutional Review Board
FDA Tue, 14 Apr 2009 00:00:00 -0400
FDA Warning Letter Issued to Coast Institutional Review Board on 14 Apr 2009 by Center for Drug Evaluation and Research
WL Issued to Branitz, Bruce, MD
FDA Thu, 09 Apr 2009 00:00:00 -0400
FDA Warning Letter Issued to Branitz, Bruce, MD on 09 Apr 2009 by Center for Drug Evaluation and Research
WL Issued to Bukowski, Ronald M, MD
FDA Mon, 30 Mar 2009 00:00:00 -0400
FDA Warning Letter Issued to Bukowski, Ronald M, MD on 30 Mar 2009 by Center for Drug Evaluation and Research
WL Issued to Youabian, Inc
FDA Tue, 17 Mar 2009 00:00:00 -0400
FDA Warning Letter Issued to Youabian, Inc on 17 Mar 2009 by Los Angeles District Office
WL Issued to Provena St. Joseph's Medical Center IRB
FDA Thu, 12 Mar 2009 00:00:00 -0400
FDA Warning Letter Issued to Provena St. Joseph's Medical Center IRB on 12 Mar 2009 by Center for Biologics Evaluation and Research
WL Issued to Paulson, Daniel M., MD
FDA Wed, 11 Mar 2009 00:00:00 -0400
FDA Warning Letter Issued to Paulson, Daniel M., MD on 11 Mar 2009 by Center for Drug Evaluation and Research

 
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'An Aspirin a Day' -- Just Another Cliché? - FDA article for general audiences discusses how this medication works, its uses, its potential role in prevention of heart attacks.
Meta Description: [ An Aspirin a Day ... Just Another Cliche? ]

A History of Aspirin - Very consice and tells the full story, not a skimmed out version.

Alka-Seltzer - Features information about this line of heartburn and cold relief products. [Requires Flash]
Meta Description: [ Alka-Seltzer relieves your hearburn and pain, and Alka-Seltzer Plus to break up your worst cold symptoms. ]

Anadin - Information for UK residents about this line of painkillers.
Meta Description: [ Anadin - When only fast will do. Our range of products provide fast pain relief from headaches, colds & 'flu, and other common conditions. ]

Aspirin - History.

Aspirin Foundation - Information about this medication and its use.

Aspirin.ca - (Canada) - The official Canadian Aspirin website providing information on back pain and arthritis pain relief using Bayer Inc.'s acetylsalicylic acid.

Aspirin: Old Standby is the New Wonder Drug - Is aspirin right for everyone? For those at risk for coronary heart disease, yes, unless it irritates their stomachs or there is some other contraindication, says Dr. David Gutterman, a specialist in internal medicine and cardiovascular disease.
Meta Description: [ Is aspirin right for everyone? ]

Bayer Aspirin - Information about heart attack prevention and the pain reliever.
Meta Description: [ Use this site to learn more about how Bayer Aspirin can help relieve pain and reduce the risks of heart attack and stroke. Learn how aspirin can help you live a more active, healthy life. ]

DrugDigest: Aspirin - Information on dosage, usage, side effects, interactions, and drug comparisons including generics.

Ecotrin Aspirin - Aspirin product that differentiates itself with its SensiCoat coating. Consumer site that offers coupons and tips for a heart healthy lifestyle.
Meta Description: [ Find out why Safety Coated Ecotrin Aspirin is the #1 Cardiologist Recommended aspirin for heart health. ]

eMedicine Health - Aspirin Poisoning - A consumer health resource center providing an overview of the causes, symptoms, and treatment of aspirin poisoning.
Meta Description: [ Aspirin is a trade name for acetylsalicylic acid, a common pain reliever (also called an analgesic). The earliest known uses of the drug can be traced back to the Greek ... ]

GPnotebook - Aspirin - Features uses and side effects of the pill.

Medinfo: Aspirin - Easy to understand information for patients on aspirin (acetylsalicylic acid).
Meta Description: [ Medinfo's patient information on Aspirin (acetylsalicylic acid), an anti-inflammatory pain killer (NSAID), which is extensively used, worldwide, for pain relief, to reduce inflammation and temperatures, and to reduce the risk of heart attacks and strokes. ]

National Reye's Syndrome Foundation - Aspirin or Salicylate-Containing Medications - Discusses the association between the development of Reye's Syndrome and the use of aspirin. Provides a list of medications that contain aspirin or salicylates.

Review of Aspirin / Reye's Syndrome Warning Statement - Information about the Australian government's re-examination of the evidence linking aspirin use in children or teenagers with chicken pox, influenza or fever, with Reye's Syndrome.
Meta Description: [ At its meeting on 3 April 2003, the Medicines Evaluation Committee agreed to re-examine the evidence linking aspirin use in children or teenagers with chicken pox, influenza or fever, with Reye's Syndrome, with a view to making further recommendations to the NDPSC about the advisability of adopti... ]

St Joseph's Aspirin - Informational site on St.Joseph's brand, including details on the 81mg dose of aspirin therapy for heart disease.

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