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Amantadine (1-aminoadamantane, sold as Symmetrel®) is an antiviral drug that was approved by the Food and Drug Administration in 1976 for the treatment of Influenzavirus A in adults. The drug has also been demonstrated to help reduce symptoms of Parkinson's disease and drug-induced extrapyramidal syndromes. As an antiparkinsonic it can be used as monotherapy; or together with L-DOPA to treat L-DOPA-related motor fluctuations (i.e., shortening of L-DOPA duration of clinical effect, probably related to progressive neuronal loss) and L-DOPA-related dyskinesias (choreiform movements associated with long-term L-DOPA use, probably related to chronic pulsatile stimulation of dopamine receptors). Amantadine has been shown to relieve SSRI-induced anorgasmia in some people, though not in all people.
It is a derivate of adamantane, like a similar drug rimantadine.
Mechanism of its effects
The mechanism of its antiparkinsonic effect is not fully understood, but it appears to be releasing dopamine from the nerve endings of the brain cells, together with stimulation of norepinephrine response. More on [ Amantadine ]
@PeterBrownPsy our Dr used amantadine to bypass damage and let brain rewire better. It worked on our son. #TBI
dreamsoftomorow (Marie Ginder) Tue, 05 Jan 2010 02:19:26 -0000
@PeterBrownPsy our Dr used amantadine to bypass damage and let brain rewire better. It worked on our son. #TBI
Amantadine to Prevent Influenza http://bit.ly/6Q3obz
boncle (alf) Mon, 04 Jan 2010 08:38:13 -0000
Amantadine to Prevent Influenza http://bit.ly/6Q3obz
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Influenza (prophylaxis) - amantadine, oseltamivir and zanamivir http://tinyurl.com/ydfmoye #influenza
SwineFluNewsUSA (Ken Wright) Sat, 02 Jan 2010 02:04:42 -0000
Influenza (prophylaxis) - amantadine, oseltamivir and zanamivir http://tinyurl.com/ydfmoye #influenza
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Amantadine Hydrochloride side effects for a male aged 69 who has Parkinson's Disease by eHealthMe http://bit.ly/5MouaT
eHealthMe (eHealthMe.com) Tue, 29 Dec 2009 02:59:14 -0000
Amantadine Hydrochloride side effects for a male aged 69 who has Parkinson's Disease by eHealthMe http://bit.ly/5MouaT
MedlinePlus: Amantadine - Features information about dosage, usage, warnings, and side effects.
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