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Acetylcysteine (rINN) (IPA: ), also known as N-acetylcysteine (abbreviated NAC), is a pharmacological agent used mainly as a mucolytic and in the management of paracetamol overdose. For these indications, acetylcysteine is available under the trade names Mucomyst (Bristol-Myers Squibb) and Parvolex (GSK).
Dosage forms
Acetylcysteine is available in different dosage forms for different indications:
- Solution for inhalation (Mucomyst, Mucosil) – inhaled for mucolytic therapy or ingested for nephroprotective effect
- IV injection (Parvolex) – treatment of paracetamol overdose
- Oral solution – various indications
The IV injection and inhalation preparations are generally prescription only, while oral solution is available over the counter in many countries.
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