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Abacavir (ABC) is the most powerful nucleoside analog reverse transcriptase inhibitor (NARTI) used to treat HIV and AIDS. It is available under the trade name Ziagen™ (GlaxoSmithKline} and the combination drugs Trizivir™(abacavir, zidovodine and lamivudine) and Kivexa®/Epzicom™(abacavir and lamivudine) . It has been well tolerated; its main side effect being hypersensitivity reactions, which can be dangerous or even (in some rare cases) fatal. Fortunately, genetic testing can indicate beforehand whether an individual will be hypersensitive; over 90% of patients can safely take abacavir.
Viral strains that are resistant to zidovudine (AZT) or lamivudine (3TC) are generally sensitive to abacavir, whereas strains that are resistant to AZT and 3TC are not as sensitive to abacavir. __NOTOC__
History
Abacavir was approved by the Food and Drug Administration (FDA) on December 18, 1998 and is thus the fifteenth approved antiretroviral drug in the United States. Its patent will expire in the United States on 2009-12-26. More on [ Abacavir ]
N Engl J Med: Abacavir-Lamivudine versus Tenofovir-Emtricitabine for Initial HIV-1 Therapy. www.amedeo.com/c.php?i=19952143
AmedeoSelection (Amedeo Selection) Thu, 10 Dec 2009 17:51:24 -0000
N Engl J Med: Abacavir-Lamivudine versus Tenofovir-Emtricitabine for Initial HIV-1 Therapy. www.amedeo.com/c.php?i=19952143
Tenofovir-Emtricitabine May Be Preferred to Abacavir-Lamivudine: Time to virologic failure and time to the first ad... http://bit.ly/7u5d4c
MsMSimons (Mallory Simons) Mon, 07 Dec 2009 19:44:29 -0000
Tenofovir-Emtricitabine May Be Preferred to Abacavir-Lamivudine: Time to virologic failure and time to the first ad... http://bit.ly/7u5d4c
Abacavir - Antiretroviral, reverse transcriptase inhibitor.
Abacavir, Zidovudine, and Lamivudine - AidsMeds.com - Consumer information on Trizivir with links to forums, general AIDS topics, and other resources for AIDS patients.
Meta Description: [ Complete info about Trizivir (abacavir + AZT + 3TC), a nucleoside analogue & treatment for HIV & AIDS. ]
DrugDigest: Abacavir ( Ziagen ) - Information on dosage, usage, side effects, interactions, and drug comparisons including generics when available.
MedlinePlus: Abacavir - Features information about dosage, usage, warnings, and side effects.
Meta Description: [ Abacavir ]
MedlinePlus: Abacavir and Lamivudine (Systemic) - Features information about dosage, usage, warnings, and side effects.
Meta Description: [ Abacavir(Systemic) ]
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Ziagen - Product information for US residents in PDF format. [Acrobat Reader required]
Meta Description: [ About GSK summarizes the mission of GSK and provides users with an overview of the organization and biographies of our Board of Directors and Corporate Executive Team. ]
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