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<title>Permanent Orthopedic Hand Job in Temecula California with Universal Health Services, Inc.</title>
<link>http://www.physemp.com/physician_jobs/all_orthopedic_hand_jobs_in_california/page_1.html</link>
<description><![CDATA[ Southern California Orthopedic Hand Specialist Opportunity! Southwest Healthcare System in Temecula, CA is assisting an Orthopedic Surgery group in their recruitment of an Orthopedic Surgeon / Hand Specialist. ]]></description>
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<link>http://www.physemp.com/physician_jobs/all_orthopedic_hand_jobs_in_kentucky/page_1.html</link>
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<item rdf:about="http://news.google.com/news/url?sa=T&#x26;ct=us/0-0&#x26;fd=R&#x26;url=http://in.reuters.com/article/health/idINPAT67653920080826&#x26;cid=1240196779&#x26;ei=fcm1SJmIDpC--AGlnKXuCg&#x26;usg=AFQjCNEEe1UCzj7upRvrVlMHzdSKpBhTXw">
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<item rdf:about="http://news.google.com/news/url?sa=T&#x26;ct=us/3-0&#x26;fd=R&#x26;url=http://www.rd.com/blogs/healthy-dose/it-is-brain-surgery/post5848.html&#x26;cid=1239033640&#x26;ei=fcm1SJmIDpC--AGlnKXuCg&#x26;usg=AFQjCNEn8Er19rF2LmhSjVkBa_4xeoSvbg">
<title>It IS Brain Surgery - Reader&#x27;s Digest</title>
<link>http://news.google.com/news/url?sa=T&#x26;ct=us/3-0&#x26;fd=R&#x26;url=http://www.rd.com/blogs/healthy-dose/it-is-brain-surgery/post5848.html&#x26;cid=1239033640&#x26;ei=fcm1SJmIDpC--AGlnKXuCg&#x26;usg=AFQjCNEn8Er19rF2LmhSjVkBa_4xeoSvbg</link>
<description><![CDATA[It IS Brain SurgeryReader's Digest,&nbsp;NY&nbsp;- 6 hours agoBut if even a little blood does leak out of one, it will cause severe pain or pressure in the head,  neck stiffness, and sensitivity to light. ...]]></description>
</item>

<item rdf:about="http://news.google.com/news/url?sa=T&#x26;ct=us/4-0&#x26;fd=R&#x26;url=http://www.sciencedaily.com/releases/2008/08/080818183938.htm&#x26;cid=1238143089&#x26;ei=fcm1SJmIDpC--AGlnKXuCg&#x26;usg=AFQjCNFkrfkSeyA65ot9v2bVOikfCHSUog">
<title>Study Examines Association Of Smoking With Hemorrhage After Throat ... - Science Daily (press release)</title>
<link>http://news.google.com/news/url?sa=T&#x26;ct=us/4-0&#x26;fd=R&#x26;url=http://www.sciencedaily.com/releases/2008/08/080818183938.htm&#x26;cid=1238143089&#x26;ei=fcm1SJmIDpC--AGlnKXuCg&#x26;usg=AFQjCNFkrfkSeyA65ot9v2bVOikfCHSUog</link>
<description><![CDATA[Study Examines Association Of Smoking With Hemorrhage After Throat ...Science Daily (press release)&nbsp;- Aug 18, 2008... tonsillectomy alone, according to a report in the August issue of Archives of Otolaryngology−Head &amp; Neck Surgery, one of the JAMA/Archives journals. ...]]></description>
</item>

<item rdf:about="http://news.google.com/news/url?sa=T&#x26;ct=us/5-0&#x26;fd=R&#x26;url=http://www.foxnews.com/story/0,2933,411482,00.html&#x26;cid=0&#x26;ei=fcm1SJmIDpC--AGlnKXuCg&#x26;usg=AFQjCNHwJL6VhQUKdtxTPa5carWGJ_ZPmA">
<title>A New Face for Teenager Born Without Jaw - FOXNews</title>
<link>http://news.google.com/news/url?sa=T&#x26;ct=us/5-0&#x26;fd=R&#x26;url=http://www.foxnews.com/story/0,2933,411482,00.html&#x26;cid=0&#x26;ei=fcm1SJmIDpC--AGlnKXuCg&#x26;usg=AFQjCNHwJL6VhQUKdtxTPa5carWGJ_ZPmA</link>
<description><![CDATA[A New Face for Teenager Born Without JawFOXNews&nbsp;- 7 hours agoDuring the final facial contouring procedure — which Rose described as the refinement and sculpting surgery – he and his team sculpted the teenager’s neck, ...]]></description>
</item>

<item rdf:about="http://news.google.com/news/url?sa=T&#x26;ct=us/6-0&#x26;fd=R&#x26;url=http://www.washingtonpost.com/wp-dyn/content/article/2008/08/22/AR2008082202326.html&#x26;cid=1239174295&#x26;ei=fcm1SJmIDpC--AGlnKXuCg&#x26;usg=AFQjCNHUbeq8hZ4nnUgvYjxP1IfmOF8m9w">
<title>Smokers More Likely to Bleed After Throat Surgery - Washington Post</title>
<link>http://news.google.com/news/url?sa=T&#x26;ct=us/6-0&#x26;fd=R&#x26;url=http://www.washingtonpost.com/wp-dyn/content/article/2008/08/22/AR2008082202326.html&#x26;cid=1239174295&#x26;ei=fcm1SJmIDpC--AGlnKXuCg&#x26;usg=AFQjCNHUbeq8hZ4nnUgvYjxP1IfmOF8m9w</link>
<description><![CDATA[Smokers More Likely to Bleed After Throat SurgeryWashington Post,&nbsp;United States&nbsp;- Aug 22, 20085.4 percent. The findings were published in the August issue of the journalArchives of Otolaryngology--Head &amp; Neck Surgery.]]></description>
</item>

<item rdf:about="http://news.google.com/news/url?sa=T&#x26;ct=us/7-0&#x26;fd=R&#x26;url=http://www.arktimes.com/Articles/ArticleViewer.aspx%3FArticleID%3Dc7a3601f-28df-486c-a02b-5b80e49e1b3f&#x26;cid=0&#x26;ei=fcm1SJmIDpC--AGlnKXuCg&#x26;usg=AFQjCNGmSR0YlQ0GraDP5akxnXLEjMJQFA">
<title>GRAVES HEARNSBERGER - Arkansas Times</title>
<link>http://news.google.com/news/url?sa=T&#x26;ct=us/7-0&#x26;fd=R&#x26;url=http://www.arktimes.com/Articles/ArticleViewer.aspx%3FArticleID%3Dc7a3601f-28df-486c-a02b-5b80e49e1b3f&#x26;cid=0&#x26;ei=fcm1SJmIDpC--AGlnKXuCg&#x26;usg=AFQjCNGmSR0YlQ0GraDP5akxnXLEjMJQFA</link>
<description><![CDATA[GRAVES HEARNSBERGERArkansas Times,&nbsp;AR&nbsp;- 31 minutes agoHearnsberger and his wife left Rogers for Little Rock when they found out twins were on the way; Dr. James Suen, the noted head and neck cancer surgeon at ...]]></description>
</item>

<item rdf:about="http://news.google.com/news/url?sa=T&#x26;ct=us/8-0&#x26;fd=R&#x26;url=http://www.411mania.com/wrestling/columns/83758/The-Piledriver-Report-08.27.08:--The-Aftermath-of-Cenas-Injury.htm&#x26;cid=1240096913&#x26;ei=fcm1SJmIDpC--AGlnKXuCg&#x26;usg=AFQjCNFTsD-bYd0-GgF5vaVlWcj_urg8BQ">
<title>The Piledriver Report 08.27.08: The Aftermath of Cena&#x2019;s Injury - 411mania.com</title>
<link>http://news.google.com/news/url?sa=T&#x26;ct=us/8-0&#x26;fd=R&#x26;url=http://www.411mania.com/wrestling/columns/83758/The-Piledriver-Report-08.27.08:--The-Aftermath-of-Cenas-Injury.htm&#x26;cid=1240096913&#x26;ei=fcm1SJmIDpC--AGlnKXuCg&#x26;usg=AFQjCNFTsD-bYd0-GgF5vaVlWcj_urg8BQ</link>
<description><![CDATA[The Piledriver Report 08.27.08: The Aftermath of Cena’s Injury411mania.com,&nbsp;TX&nbsp;- 17 hours agoYoungblood has performed neck surgery on many WWE stars including Steve Austin, Edge, and Lita. There is a fear that Cena&#39;s injury is far worse than just ...]]></description>
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<item rdf:about="http://news.google.com/news/url?sa=T&#x26;ct=us/9-0&#x26;fd=R&#x26;url=http://www.marketwatch.com/news/story/reminder-orlive-presents-advances-parotidectomy/story.aspx%3Fguid%3D%257BAD53AAD6-6C53-464F-970D-11128B5C2252%257D%26dist%3Dhppr&#x26;cid=1232139456&#x26;ei=fcm1SJmIDpC--AGlnKXuCg&#x26;usg=AFQjCNESj8xqD3xMvjJ_LSMhF9qXIOhzWg">
<title>REMINDER: ORLive Presents: Advances in Parotidectomy and Minimally ... - MarketWatch</title>
<link>http://news.google.com/news/url?sa=T&#x26;ct=us/9-0&#x26;fd=R&#x26;url=http://www.marketwatch.com/news/story/reminder-orlive-presents-advances-parotidectomy/story.aspx%3Fguid%3D%257BAD53AAD6-6C53-464F-970D-11128B5C2252%257D%26dist%3Dhppr&#x26;cid=1232139456&#x26;ei=fcm1SJmIDpC--AGlnKXuCg&#x26;usg=AFQjCNESj8xqD3xMvjJ_LSMhF9qXIOhzWg</link>
<description><![CDATA[Market Wire (press release)REMINDER: ORLive Presents: Advances in Parotidectomy and Minimally ...MarketWatch&nbsp;- Jul 30, 2008The webcast will also feature an informative didactic segment on surgical techniques used in head and neck surgery. Viewers may participate in the program ...New Minimally Invasive Surgical Procedure Restores Quality of Life ... MarketWatchall 14 news articles]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20979">
<title>Eliminating healthcare disparities in America: Beyond the IOM report</title>
<link>http://dx.doi.org/10.1002%2Fhed.20979</link>
<description><![CDATA[No abstract.]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20881">
<title>Pharyngeal swallowing dysfunction following treatment for oral and pharyngeal cancer - Association with diminished intraoral sensation and discrimination ability</title>
<link>http://dx.doi.org/10.1002%2Fhed.20881</link>
<description><![CDATA[Swallowing disorders following treatment for oral and pharyngeal cancer are mainly considered a surgical sequel. The recent finding that radiotherapy-induced decline in intraoral sensory abilities established an incentive to elucidate any association between the degree of sensory decline and the degree of swallowing dysfunction.Oral and pharyngeal swallowing was cineradiographically examined in 15 patients with oral or pharyngeal cancer before and after treatment. The patients were also tested for intraoral sensation, shape recognition, and hole size identification.Swallowing function deteriorated in 67% of the patients 6 months posttreatment, with no significant improvement after 12 months. The degree of swallowing dysfunction was statistically significantly associated with the degree of diminished intraoral sensation and shape recognition.In the quest for rehabilitation after treatment for oral and pharyngeal cancer, the impact of impaired intraoral sensation and discrimination ability on swallowing function should be taken into consideration. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20884">
<title>Speech outcomes after soft palate reconstruction with the soft palate insufficiency repair procedure</title>
<link>http://dx.doi.org/10.1002%2Fhed.20884</link>
<description><![CDATA[Measurement of functional outcomes related to different methods of soft palate reconstruction is necessary to determine efficacy of surgical intervention after resection for oropharyngeal cancer.Speech data were collected across 4 evaluation times for 4 groups of patients (2 groups consisted of patients with [le] half the soft palate resected followed by conventional reconstruction; 2 groups consisted of patients with half or more of the soft palate resected followed by reconstruction with an adhesion or the soft palate insufficiency repair (SPIR).Sixty-two patients were included. Speech was preserved when conventional reconstructive procedures were used to close smaller defects. For larger defects, reconstruction with an adhesion resulted in poorer speech outcomes than the SPIR. The SPIR group achieved normal speech results at all points of evaluation.The results demonstrate that the SPIR is emerging as an efficacious surgical technique for reconstruction of larger soft palate defects. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20880">
<title>Atelectasis after free rectus transfer and abdominal wall reconstruction</title>
<link>http://dx.doi.org/10.1002%2Fhed.20880</link>
<description><![CDATA[Atelectasis is commonly encountered in patients undergoing rectus abdominus tissue transfer. Primary closure of the anterior rectus sheath may contribute to this process. Augmentation of the closure with mesh may decrease the incidence of Atelectasis.In this retrospective review 32 patients with preoperative and postoperative augmentation were compared to 23 who had primary closure of the anterior rectus sheath.Augmentation consisted of acellular dermis (25) ormesh (7). Postoperative atelectasis was radiographically detected in: 91% (n = 29) of augmented patients versus 83% (n = 19) of primary closure patients. Major atelectasis in 41% (n= 13) of augmented patients versus 61% (n = 14) of primary closure patients p <.05. The incidence of atelectasis was independent of skin flap size and operative times.The use of acellular dermis or mesh to augment the abdominal wall appears to reduce the high incidence of postoperative atelectasis following rectus-free flap harvest. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20879">
<title>Nomogram for deciding adjuvant treatment after surgery for oral cavity squamous cell carcinoma</title>
<link>http://dx.doi.org/10.1002%2Fhed.20879</link>
<description><![CDATA[The application of appropriate adjuvant treatment after surgery for oral cavity squamous cell carcinoma (OCSCC) is predicated on accurate patient risk stratification.A nomogram for estimating locoregional recurrence-free survival (LRFS) after treatment of OCSCC was constructed from a cohort of 590 patients with OCSCC who were treated at Memorial Sloan-Kettering Cancer Center (MSKCC). The nomogram was validated using a series of 417 patients with OCSCC who were treated at Hospital do Cancer AC Camargo (HACC) in São Paulo, Brazil.Despite significant differences between the MSKCC and HACC cohorts, the nomogram was able to predict LRFS from OCSCC with a concordance index of 0.693. Further statistical analysis showed that the nomogram was well calibrated.This preliminary nomogram is the first prognostic model developed and externally validated to predict the likelihood of LRFS after treatment for an individual patient with OCSCC and may have practical utility for deciding adjuvant treatment. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20908">
<title>E-cadherin loss and [Delta]Np73L expression in oral squamous cell carcinomas showing aggressive behavior</title>
<link>http://dx.doi.org/10.1002%2Fhed.20908</link>
<description><![CDATA[This article sought to investigate the existence of parameters useful for predicting lymph node metastases in cases of surgically resected oral squamous cell carcinomas (OSCCs).Fifty-eight cases were studied for E-cadherin and the truncated dominant-negative isoform of p63 ([Delta]Np63) with immunohistochemistry. In addition, the p63 gene expression profile was evaluated by reverse transcriptase-polymerase chain reaction (RT-PCR) to disclose the presence of the truncated variant [Delta]Np73L.E-cadherin expression was the most powerful parameter related to the presence of lymph node metastases at presentation. Twenty-four of 38 (63%) cases showing low E-cadherin expression had lymph node metastases at presentation compared with 5 of 20 (25%) (p < .01) cases showing high E-cadherin expression. The high predictive value was also maintained when a low expression of E-cadherin was associated with immunohistochemical high expression of [Delta]Np63. The association between low E-cadherin expression and [Delta]Np73L (as seen with reverse transcriptase-polymerase chain reaction) was highly predictive for developing lymph node metastases, especially in small tumors (T1\T2). When this association occurred, metastases developed in 62.5% of cases during the follow-up compared with 16.1% in those which did not show low E-cadherin expression and presence of [Delta]Np73L.This study shows that low E-cadherin expression is useful for predicting lymph node metastases in cases of OSCC. The predictive value is enhanced when low E-cadherin positivity is associated with [Delta]Np63 and [Delta]Np73L expression. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20905">
<title>Evolution of maxillofacial brown tumors after parathyroidectomy in primary hyperparathyroidism</title>
<link>http://dx.doi.org/10.1002%2Fhed.20905</link>
<description><![CDATA[Brown tumor occasionally affects the facial bones. Clinically, these lesions can be mistaken for a neoplasm. Opinions are divided on the course of management of the bony lesions once parathyroidectomy has been carried out.We treated 22 patients with primary hyperparathyroidism and osteitis fibrosa cystica and observed their clinical and biochemical recovery.Fifteen patients (68.2%) had brown tumors in mandible, and 7 (31.8%) in maxilla. After parathyroidectomy, 21 patients had normal total serum calcium values. All brown tumors presented a spontaneous progressive regression; in 18cases, regression was total, with a mean time period of 10months. Two patients had partial regression after nearly 2years. Another 2 patients were lost to follow-up.After successful parathyroid surgery, the bony lesions tended to regress spontaneously, either partially or completely. However, if the lesion is disfiguring or symptomatic, surgical excision may be indicated. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20904">
<title>Predictors of level V metastasis in well-differentiated thyroid cancer</title>
<link>http://dx.doi.org/10.1002%2Fhed.20904</link>
<description><![CDATA[Cervical lymphadenectomy is frequently performed in patients with lateral cervical lymph node metastases to improve regional control of disease. However, there is no consensus regarding the appropriate levels of the neck that need to be dissected. Treatment options that have been advocated include the modified radical neck dissection, limited neck dissections, and selective nodal excisions. In particular, the routine dissection of level V remains controversial due to the attendant morbidity to the spinal accessory nerve. To identify clinical and pathological predictors of cervical node metastases to level V in differentiated thyroid carcinoma, we reviewed our experience at The University of Texas M. D. Anderson Cancer Center for the management of metastatic well-differentiated thyroid cancer.We retrospectively analyzed 70 patients who underwent thyroidectomy and neck dissection for well-differentiated thyroid cancer at M. D. Anderson Cancer Center.In our series, 53% of neck specimens harbored metastatic thyroid carcinoma at level V. Additionally, 13 level V contralateral neck dissections were performed, and 57% were found positive for metastases. The presence of ipsilateral level V metastases was significantly associated with multifocal disease (p <.05), ipsilateral level II (p <.05), III (p <.05), or IV (p <.01) metastases. Furthermore, ipsilateral involvement of level V was associated with contralateral lymph node metastases (p <.05). Age, sex, and size of primary tumor were not found to be associated with level V metastases. Additionally, preoperative imaging was not sensitive for detecting the presence of level V metastases.In our series, cervical metastases from differentiated thyroid carcinoma were commonly present at level V. Patients with multifocal cancer within the thyroid gland, and cervical metastases in the ipsilateral jugular nodes have a higher risk of harboring metastatic disease at level V. We believe that routine dissection of the level V lymph nodes should be performed in the setting of a comprehensive neck dissection for patients with lateral neck metastasis from well-differentiated thyroid cancer. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20903">
<title>Ultrasound-guided aspiration cytology for the assessment of the clinically N0 neck: Factors influencing its accuracy</title>
<link>http://dx.doi.org/10.1002%2Fhed.20903</link>
<description><![CDATA[Ultrasound-guided fine-needle aspiration cytology (US-FNAC) can be used to diminish the risk of missing occult metastases and for early detection during follow-up.A retrospective study was performed in 163 surgically treated patients without palpable neck nodes (N0). One hundred twenty-six patients underwent planned elective neck dissections, and 37 were planned for a wait-and-see strategy, but preoperative US-FNAC could change this policy if metastases were detected.In the elective neck dissection group, US-FNAC had a sensitivity of 39%, whereas in the wait-and-see group, the sensitivity was 18%. The 5-year survival in the wait-and-see group did not differ from the patients with early oral cancer who underwent an elective neck dissection.Although the sensitivity of US-FNAC in this study is low, especially in small oral cancer, the prognosis in the wait-and-see group is not affected. However, a wait-and-see strategy is only advantageous to a minority of the patients. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20902">
<title>Clinical predictors of larynx preservation after multiagent concurrent chemoradiotherapy</title>
<link>http://dx.doi.org/10.1002%2Fhed.20902</link>
<description><![CDATA[Determining which patients benefit from larynx preservation strategies remains problematic. We reviewed our experience using multiagent concurrent chemoradiotherapy to identify clinical predictors for success.Cisplatin and fluorouracil were given during weeks 1 and 4 of radiation to 115 patients with locoregionally advanced larynx or hypopharynx squamous cell cancer without cartilage invasion or laryngeal destruction. Laryngectomy was reserved for local failure.The 5-year Kaplan-Meier projected overall survival was 58%, survival with larynx preservation 52%, local control without surgery 82%, local control (including surgical salvage) 94%, and survival with functional larynx 49%. Local control without surgery was superior in patients with T1-2 versus T3-4 tumors (97% vs 77%, p = .032). No other clinical parameters proved predictive of local control.Larynx preservation was successful in all subsets of appropriately selected patients. Although local failure was more likely in patients with T3-4 tumors, it was infrequent and surgical salvage was effective. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20901">
<title>Head and neck mucosal melanoma: Experience with 42 patients, with emphasis on the role of postoperative radiotherapy</title>
<link>http://dx.doi.org/10.1002%2Fhed.20901</link>
<description><![CDATA[Treatment of head and neck mucosal melanoma remains a challenge. Surgery has traditionally been the main therapeutic approach. The role of postoperative radiotherapy has never been clearly established.The experience with a group of 42 patients (16 males, 26 females) with a primary head and neck mucosal melanoma is reported.Eleven of 19 patients (57.9%) receiving surgery alone developed a regional lymphatic metastasis. For patients receiving postoperative radiotherapy (19 patients), regional metastatic spread occurred in 4 patients (21%). Percentages of local failure were 57.9% (11/19) and 26.3% (5/19) for patients treated with surgery alone and for those treated with surgery and radiotherapy, respectively. Distant metastases occurred in 10 of 19 patients (52.6%) receiving surgery alone and in 9 of 19 patients (47.3%) receiving both therapies.The present evaluation confirms a poor prognosis for patients with head and neck mucosal melanoma, independent of the treatment modality. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20900">
<title>Evaluation of postoperative drainage with application of platelet-rich and platelet-poor plasma following hemithyroidectomy: A randomized controlled clinical trial</title>
<link>http://dx.doi.org/10.1002%2Fhed.20900</link>
<description><![CDATA[Platelet-rich plasma (PRP) and platelet-poor plasma (PPP) have been used to improve hemostasis and wound healing after surgery; however, randomized controlled trials proving their efficacy are lacking.Hemithyroidectomy was performed on 52 patients. Autologous PRP and PPP were applied during wound closure in the treatment group, while saline was applied in the controls. Outcome measures were postoperative drainage, pain, analgesic use, and length of hospital stay.The 24-hour cumulative drainage was reduced by 29.3% in the treatment group (44.9 mL vs 63.5 mL, p = .039). The treatment group required less analgesic medication despite similar pain scores; however, the difference was not significant. There was a trend toward decreased length of stay for thePRP/PPP group (p = .059).Hemithyroidectomy served as a stringent test to evaluate the wound-healing capacity of platelet-rich and platelet-poor plasma. This study provides evidence that PRP and PPP reduced postoperative drainage in soft-tissue surgery. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20898">
<title>Sirolimus as a potential radiosensitizer in squamous cell cancer of the head and neck</title>
<link>http://dx.doi.org/10.1002%2Fhed.20898</link>
<description><![CDATA[An estimated 34,000 cases of squamous cell carcinomas of the head and neck (HNSCC) will be diagnosed in 2007 with 7500 estimated deaths. Radiation is commonly used to treat these patients. Preclinical studies have suggested that sirolimus may be an effective radiosensitizer in HNSCC.The present case report describes a patient, status post liver transplant, who was switched to sirolimus for immunosupression. The patient subsequently underwent radiation therapy for a T2N0M0 SCC of the larynx.The patient had an unusually early response to radiation, with a clinical complete response after 7 fractions of radiation. However, the patients also had toxicity earlier than expected and required a break from radiation after 11 fractions.To the authors' knowledge, this is the first observation to suggest that sirolimus is an effective radiosensitizer in patients with HNSCC. We hope that our results will create interest in future clinical studies. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20888">
<title>Indications of cricohyoidoepiglottopexy versus anterior frontal laryngectomy: The role of contralateral vocal fold spread</title>
<link>http://dx.doi.org/10.1002%2Fhed.20888</link>
<description><![CDATA[The aim of the retrospective study was to compare the indications, the postoperative outcomes, and the survival of the supracricoid laryngectomy with cricohyoidoepiglottopexy and the anterior frontal laryngectomy.Nineteen patients who underwent cricohyoidoepiglottopexy (group I) and 23 patients who underwent reconstructive anterior frontal laryngectomy (group II) from January 1992 and December 2004 have been reviewed. We have compared their respective indications and postoperative outcomes.There were no differences for median time before decanulation. Median time for removal feeding tube, for first oral alimentation, and hospital stay period were significantly shorter in group II. Five-year survival was 85% (group I) and 95% (group II). Local tumor control was obtained in 83% in group I and in 87% in group II.Cricohyoidoepiglottopexia (CHEP) was used more often than anterior frontal laryngectomy when there was contralateral vocal fold spread but resulted in longer postoperative outcomes. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20887">
<title>Comparison of perioperative management and outcome of parathyroidectomy between older and younger patients</title>
<link>http://dx.doi.org/10.1002%2Fhed.20887</link>
<description><![CDATA[The aim of this study was to compare the clinical status, surgical course, and outcomes of patients with primary hyperparathyroidism (PHPT), over the age of 70, with younger patients.Between 1996 and 2006, 951 patients underwent parathyroidectomies for PHPT, of whom 190 were over the age of 70. Patient data were collected from chart reviews and a computerized database.Fewer older patients were asymptomatic at presentation. No between-group differences in serum calcium were seen; however, parathyroid hormone (PTH) levels were higher in the older group. Hospitalization time was longer for the elderly. Duration of surgery, surgical success rates, and postoperative complications were similar between the 2 groups.Surgical treatment of PHPT has both physiological benefits and helps to preserve quality of life. Our findings suggest that there is no practical difference in perioperative management and surgical outcomes for older patients. Surgeons should consider parathyroidectomy in PHPT patients regardless of age. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20885">
<title>Definitive radiotherapy in the management of paragangliomas arising in the head and neck: A 35-year experience</title>
<link>http://dx.doi.org/10.1002%2Fhed.20885</link>
<description><![CDATA[An evaluation of the treatment results for 104 patients with 121 paragangliomas of the temporal bone, carotid body, and/or glomus vagale who were treated with radiation therapy (RT) at the University of Florida between 1968 and 2004.Eighty-nine paragangliomas (86%) were treated with conventional megavoltage techniques, 15 (14%) patients with stereotactic fractionated radiation therapy, 6 (6%) patients with stereotactic radiosurgery (SRS), and 11 (11%) patients with intensity-modulated radiation therapy (IMRT).There were 6 local recurrences. One recurrence was salvaged with additional RT. The actuarial local control and cause-specific survival rates at 10 years were 94% and 95%. The overall local control rate for all 121 lesions was 95%; the ultimate local control rate was 96%. The incidence of treatment-related complications was low.Fractionated RT offers a high probability of tumor control with minimal risks for patients with paragangliomas of the temporal bone and neck. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20878">
<title>Mucosal melanomas of the head and neck: The Princess Margaret Hospital experience</title>
<link>http://dx.doi.org/10.1002%2Fhed.20878</link>
<description><![CDATA[The aim of this study was to identify the prognostic variables in mucosal melanoma of the head and neck.A retrospective review of 61 cases over a 41-year period was undertaken. Local, regional, and distant failures were major outcome measures. Demographic, clinical, and pathological parameters were identified and correlated with outcomes.The median age at diagnosis was 68 years. Sinonasal cavity involvement occurred in 80.3% of patients and 16.4% occurred in the oral cavity. Local, regional, and distant recurrences were 60.7%, 19.7%, and 49.2%, respectively. Two-year and 5-year disease-free survivals were 25.8% and 8%, respectively. Disease-specific survival at 5 years was 28.7%. Age <50 years significantly correlated with a longer median survival time.The most common occurrence site was the sinonasal cavity. Local and distant recurrences are common irrespective of treatment modalities. Younger patients have a relatively better prognosis. Disseminated disease is common and the overall prognosis is poor. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20877">
<title>Cancer of the external auditory canal and middle ear in Denmark from 1992 to 2001</title>
<link>http://dx.doi.org/10.1002%2Fhed.20877</link>
<description><![CDATA[In the context of the Danish Head and Neck Cancer Group, nationwide material from 1992-2001 was analyzed to study the extent and nature of the disease, evaluate treatment, compare staging systems, and examine prognosis and survival.Review of 68 consecutive cases: 47 squamous cell carcinoma, 10 basal cell carcinoma, and 11 other histologies. Moody (modified Pittsburgh) stages were T1 (26), T2 (9), T3 (8), T4 (23), Tx (2). Sixty-four patients were treated with curative intent: 24 primary radiotherapy, 18 primary surgery, and 22 combined. Surgery was limited to tumor excision and mastoidectomy and in 1 case temporal bone excision.Twenty-seven of 28 recurrences involved primary site. Kaplan-Meier analysis showed 5-year locoregional control of 48%, disease-specific survival 57%, and overall survival 44%.This nationwide study confirmed that local failure is the main problem, and future improvements should focus on more aggressive local treatment. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20876">
<title>Survivin and epidermal growth factor receptor expression in surgically treated oropharyngeal squamous cell carcinoma</title>
<link>http://dx.doi.org/10.1002%2Fhed.20876</link>
<description><![CDATA[The epidermal growth factor receptor (EGFR) and the inhibitor of apoptosis protein survivin play important roles in the regulation of cellular proliferation and survival in squamous cell carcinomas. Their correlation in oropharyngeal squamous cell carcinoma (OSCC) has not been evaluated yet.In this multicenter study, we analyzed the expression of survivin and EGFR in tissue specimens from 73 selected patients with OSCC using immunohistochemistry.Higher cytoplasmic survivin scores were significantly correlated with high scores of EGFR expression (p = .013). Nuclear survivin expression was associated with a poor overall survival rate with an estimated 3-year overall survival probability of 17.3% versus 87.4% for non-nuclear expression of survivin (p <.001). Multivariate analysis revealed that nuclear survivin expression was an independent negative prognostic factor (p = .008).Considering the strong impact of nuclear survivin expression on survival, the survivin expression should be prospectively evaluated to select patients with an increased risk for disease recurrence. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20875">
<title>Sentinel node biopsy in patients with cutaneous melanoma of the head and neck: Recurrence and survival study</title>
<link>http://dx.doi.org/10.1002%2Fhed.20875</link>
<description><![CDATA[Controversy remains regarding the benefits of sentinel lymph node (SLN) biopsy for predicting survival in cutaneous melanoma of the head and neck (CMHN).We analyzed the factors associated with the recurrence and survival of CMHN patients treated in our institution.One hundred thirteen patients underwent SLN biopsy for CMHN in a 12-year period. SLN identification was successful in 96%, with a median of 3 SLNs per patient. Positive-SLNs were identified in 21%. With a median follow-up of 34 months, 28% recurred. Disease-free survival (DFS) and overall survival (OS) rates were 66% and 78% in patients with SLN-negative, and 39% and 62% in SLN-positive disease. In multivariate analysis, greater Breslow-thickness was associated with decreased DFS rate (HR 2.07, CI 1.04-4.09), and age >60 years (HR 3.53, CI 1.32-9.4) with lower 5-year OS rate.Primary tumor thickness and age were associated with decreased survival, whereas SLN status showed a trend for prognostic significance in CMHN. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20892">
<title>Role of proinflammatory cytokines in cisplatin-induced vestibular hair cell damage</title>
<link>http://dx.doi.org/10.1002%2Fhed.20892</link>
<description><![CDATA[Cisplatin causes the impairment of inner ear functions, including hearing and balance, through the involvement of a number of mechanisms. However, no laboratory studies have been performed on involvement of inflammation-related events in cisplatin-mediated vestibular dysfunction.We evaluated the secretion of proinflammatory cytokines and nuclear factor-[kappa]B (NF-[kappa]B) activation in cisplatin-treated UB/UE-1 utricular epithelial cells. We also employed immunohistochemistry to detect proinflammatory cytokines and NF-[kappa]B expression in cisplatin-injected mice.Productions of proinflammatory cytokines significantly caused the death of UB/UE1 cells by cisplatin. Pharmacologic inhibition of mitogen-activated protein (MAP) kinase/ERK kinase-1 (MEK1) or extracellular signal-regulated kinase (ERK) significantly attenuated the death of UB/UE1 cells caused by cisplatin and proinflammatory cytokines. Immunohistochemical studies revealed an increase in the expression of proinflammatory cytokines and NF-[kappa]B in both the cristae ampullae and utricle of cisplatin-injected mice.These results suggest that proinflammatory cytokines may play an important role in the pathogenesis of cisplatin-mediated vestibulotoxicity. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20890">
<title>Comparison of pullout strength of resorbable screws in human cadaveric laryngeal cartilage using different drill diameters</title>
<link>http://dx.doi.org/10.1002%2Fhed.20890</link>
<description><![CDATA[In a previous study at our institution, it was determined that resorbable screws with untapped drill holes resulted in the highest resistance forces to linear load when compared with titanium screws. The 1.1-mm drill diameter/2.0-mm screw diameter and 1.5/2.0 drill/screw combinations were superior to the 1.1/1.5 combinations; however, there was no conclusion as to the best screw size to drill bit diameter. The aim of this prospective study was to compare the pullout strength of resorbable screws in fresh frozen cadaveric laryngeal cartilage. The importance of drill hole diameter will also be determined.After debridement of connective tissue and perichondrium, 12 cartilage specimens were tested. Linear pullout strength of screws was measured using a load cell. Resorbable screws of size 2.0 mm were tested using drill hole diameters of 0.0 mm, 0.8 mm, and 1.5 mm. All tested screws were 6 mm in length or greater.We found no strong evidence that the means for the 0.8/2.0 and 1.5/2.0 differ or that the 0.0/2.0 and 0.8/2.0 means differ. There is evidence that the 0.0/2.0 and 1.5/2.0 means differ (adjusted p value .0108), with the 0.0/2.0 combination having a smaller mean.Resorbable screws without predrilled holes result in less resistance to linear loads than either the resorbable screws with the 0.8/2.0 or the 1.5/2.0 drill/screw combinations. The 1.5/2.0 drill/screw combination had the strongest pullout force, though this was not statistically significant. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20889">
<title>Primary squamous cell carcinoma of Stensen&#x27;s duct in a patient with HIV: The role of magnetic resonance imaging and fine-needle aspiration</title>
<link>http://dx.doi.org/10.1002%2Fhed.20889</link>
<description><![CDATA[Primary malignant tumors involving Stensen's duct are rare neoplasms, with less than 30 cases reported. We report a case of primary squamous cell carcinoma (SCC) involving Stensen's duct in a patient infected with human immunodeficiency virus (HIV) and describe the role of fine-needle aspiration (FNA) and MRI in the diagnosis of this rare entity.A 47-year-old man with HIV presented with intermittent parotid swelling and pain unresponsive to conservative treatment. He subsequently developed a mass emanating from Stensen's duct, and an MRI and ultrasound-guided FNA revealed carcinoma of Stensen's duct. Total parotidectomy with postoperative external beam radiation therapy was performed.The patient remains disease free 31 months after treatment.Primary SCC of Stensen's duct is a rare entity that may mimic benign obstructive parotid disease. FNA and MRI are useful in the diagnosis and assessment of disease extent. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20874">
<title>Zygomaticomaxillary buttress reconstruction of midface defects with the osteocutaneous radial forearm free flap</title>
<link>http://dx.doi.org/10.1002%2Fhed.20874</link>
<description><![CDATA[The purpose of this study was to evaluate morbidity, functional, and aesthetic outcomes in midface zygomaticomaxillary buttress reconstruction using the osteocutaneous radial forearm free flap (OCRFFF).A retrospective review of 24 consecutive patients that underwent midface reconstruction using the OCRFFF was performed. All patients had variable extension of maxillectomy defects that requires restoration of the zygmatico-maxillary buttress. After harvest, the OCRFFF was fixed transversely with miniplates connecting the remaining zygoma to the anterior maxilla. The orbital support was given by titanium mesh when needed that was fixed to the radial forearm bone anteriorly and placed on the remaining orbital floor posteriorly. The skin paddle was used for intraoral lining, external skin coverage, or both. The main outcome measures were flap success, donor-site morbidity, orbital, and oral complications. Facial contour, speech understandability, swallowing, oronasal separation, and socialization were also analyzed.There were 6 women and 18 men, with an average age of 66 years old (range, 34-87). The resulting defects after maxillectomy were (according to the Cordeiro classification; Disa et al, Ann Plast Surg 2001;47:612-619; Santamaria and Cordeiro, J Surg Oncol 2006;94:522-531): type I (8.3%), type II (33.3%), type III (45.8%), and type IV (12.5%). There were no flap losses. Donor-site complications included partial loss of the split thickness skin graft (25%) and 1 radial bone fracture. The most significant recipient-site complications were severe ectropion (24%), dystopia (8%), and oronasal fistula (12%). All the complications occurred in patients with defects that required orbital floor reconstruction and/or cheek skin coverage. The average follow-up was 11.5 months, and over 80% of the patients had adequate swallowing, speech, and reincorporation to normal daily activities.The OCRFFF is an excellent alternative for midface reconstruction of the zygomaticomaxillary buttress. Complications were more common in patients who underwent resection of the orbital rim and floor (type III and IV defects) or external cheek skin. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20873">
<title>Factors associated with fatigue, sleep, and cognitive function among patients with head and neck cancer</title>
<link>http://dx.doi.org/10.1002%2Fhed.20873</link>
<description><![CDATA[Fatigue, sleep disturbances, and cognitive impairment are prevalent and clinically important problems among head and neck cancer patients. Our study aim was to determine the most important correlates of these problems among patients with head and neck cancer.A cross-sectional, self-administered survey was completed by 58 (response rate 79%) patients with head and neck cancer in an academic oncology clinic.Multiple linear-regression analyses demonstrated that fatigue was associated with younger age ([beta] = -0.22), previous radiation therapy ([beta] = 0.23), fewer months since cancer diagnosis ([beta] = -0.25), and depression ([beta] = 0.40). Sleep dysfunction was associated with younger age ([beta] = -0.31) and higher symptom index ([beta] = 0.39). Cognitive dysfunction was associated with higher symptom index only ([beta] = -0.49).Younger age, previous radiation, more recent cancer diagnosis, depression, and more severe symptoms may be associated with fatigue, sleep, and/or cognitive dysfunction. These results suggest at-risk subgroups warranting more aggressive screening and potentially supportive care interventions. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20871">
<title>Molecular signatures of metastasis in head and neck cancer</title>
<link>http://dx.doi.org/10.1002%2Fhed.20871</link>
<description><![CDATA[Metastases are the primary cause of cancer treatment failure and death, yet metastatic mechanisms remain incompletely understood.We studied the molecular basis of head and neck cancer metastasis by transcriptionally profiling 70 samples from 27 patients - matching normal adjacent tissue, primary tumor, and cervical lymph node metastases.We identified tumor-associated expression signatures common to both primary tumors and metastases. Use of matching metastases revealed an additional 46 dysregulated genes associated solely with head and neck cancer metastasis. However, despite being metastasis-specific in our sample set, these 46 genes are concordant with genes previously discovered in primary tumors that metastasized.Although our data and related studies show that most of the metastatic potential appears to be inherent to the primary tumor, they are also consistent with the notion that a limited number of additional clonal changes are necessary to yield the final metastatic cell(s), albeit in a variable temporal order. © 2008 Wiley Periodicals, Inc. Head Neck 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20868">
<title>Association between self-esteem and depression among patients with head and neck cancer: A pilot study</title>
<link>http://dx.doi.org/10.1002%2Fhed.20868</link>
<description><![CDATA[We examined the psychological distress in patients with head and neck cancer and investigated how preoperative self-esteem influenced psychological distress during treatment.Fifty-eight patients who were scheduled for surgery for head and neck cancer participated. The Japanese version of hospital anxiety and depression scale (HADS) was administered preoperatively, after surgery, and 6 months postoperatively, and Rosenberg self-esteem scale was administered preoperatively and 6 months postoperatively.There were significant differences among the 3 examination periods for psychological distress; the course of anxiety and depression differed between the high self-esteem group (HSEG) and the low self-esteem group (LSEG). In all examination periods, anxiety and depression scores for HSEG were significantly better than for LSEG. As for depression, scores did not change significantly over time in HSEG, whereas the scores went from bad to worse in LSEG.Patients with cancer undergoing surgery, especially patients with low self-esteem, need preoperative and ongoing intervention. © 2008 Wiley Periodicals, Inc. Head Neck 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20863">
<title>State of head and neck surgical oncology research - A review and critical appraisal of landmark studies</title>
<link>http://dx.doi.org/10.1002%2Fhed.20863</link>
<description><![CDATA[Surgical literature has been criticized for the lack of high-quality research. The present review examines methodological quality of literature published in head and neck surgical oncology. We focus on landmark studies published on topics of best practice controversy, namely (1) the role of chemotherapy and organ-preservation protocols in the management of head and neck mucosal malignancies; (2) the role of selective neck dissection versus radical neck dissection; and (3) the role of laser microsurgery in the management of larynx cancer. Similar flaws were evident in selected landmark studies with the major issue being multiplicity in the form of multiple outcome analysis, comparison of multiple treatment groups, repeated measures over time, planned interim analyses, and subgroup analyses. The open nonrandomized controlled trial may be a feasible option in head and neck surgical research allowing for standardization, uniformity, consistency, and blinded outcome assessment. © 2008 Wiley Periodicals, Inc. Head Neck 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20861">
<title>DNA copy number variation and loss of heterozygosity in relation to recurrence of and survival from head and neck squamous cell carcinoma: A review</title>
<link>http://dx.doi.org/10.1002%2Fhed.20861</link>
<description><![CDATA[Genetic aberrations, such as DNA copy number variation (CNV) and loss of heterozygosity (LOH), have been implicated in head and neck squamous cell carcinoma (HNSCC) initiation and progression. This review examines CNV and LOH as predictors of HNSCC recurrence and mortality. We searched PubMed for relevant publications and compared and discussed results from the articles. Certain CNV and LOH events have consistently been associated with HNSCC recurrence and survival. The recent high-resolution single nucleotide polymorphism (SNP) arrays have the potential to identify many more genetic changes and concurrent genome-wide CNV, copy-neutral and/or allelic imbalance LOH in HNSCC that may bear on prognosis. Our review confrms that outcome in HNSCC can be predicted to a considerable extent by the presence of tumor cell genetic aberrations. It points out the limitations of some methodologies that were used in the past and discusses the advantages and challenges of using genome-wide SNP arrays. © 2008 Wiley Periodicals, Inc. Head Neck 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20860">
<title>Survival of patients with neck recurrence following radical neck dissection: Utility of a second neck dissection?</title>
<link>http://dx.doi.org/10.1002%2Fhed.20860</link>
<description><![CDATA[Treatment of neck recurrence following radical neck dissection is extremely difficult. Retrospective review of 699 radical neck dissections was performed. Recurrence rates, host, tumor, treatment factors, and survival were analyzed. One hundred nineteen patients who had undergone radical neck dissections had recurrence, 69 were considered candidates for salvage surgery. Factors that increased the risk of neck recurrence were neck node (N) status and no adjuvant radiotherapy. Factors associated with radical salvage treatment were young age, good general condition, and low recurrent N classification. Five-year survival for salvage neck dissection was 31%. Young patients and low T and N classification did well. Low recurrent N classification and salvage surgery were associated with good prognosis for recurrence. In our study, radical neck dissection has a regional failure rate of 20%, a third of recurrence cases were offered curative treatment. Of these, 31% were cured with salvage surgery. © 2008 Wiley Periodicals, Inc. Head Neck 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20856">
<title>Synovial sarcoma of the head and neck: Rare case of cervical metastasis</title>
<link>http://dx.doi.org/10.1002%2Fhed.20856</link>
<description><![CDATA[Synovial sarcoma is a rarely encountered soft tissue sarcoma. Surgery with a wide surgical margin is the treatment of choice. However, there is no consensus on the treatment of head and neck synovial sarcoma in patients with cervical metastasis.A 20-year-old man was seen with a palpable mass in the right neck. He had been diagnosed with synovial sarcoma of the right tonsil and treated by surgery 1 and a half years before; therefore, the mass detected was thought to be a cervical metastasis of synovial sarcoma. We performed a modified radical neck dissection with no postoperative treatment. The pathological diagnosis was confirmed by detecting the SS-specific fusion gene SYT-SSX1.The patient remains free of recurrence or metastasis 2 years and 10 months after the surgery.We encountered a case of head and neck synovial sarcoma with cervical metastasis that was successfully treated. © 2008 Wiley Periodicals, Inc. Head Neck 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20855">
<title>Pseudoaneurysm of the external carotid artery - Review of literature</title>
<link>http://dx.doi.org/10.1002%2Fhed.20855</link>
<description><![CDATA[Pseudoneurysms of the carotid artery are rarely encountered in clinical practice. When encountered they are most likely secondary to acute neck trauma, and involve the internal carotid. External carotid artery involvement is very rare.We report a case of an external carotid aneurysm following a neck dissection review the literature and discuss the investigation and management of these unusual lesions.Incidence is 0.07%, but mortality can be as high as 30%. Clinical features include swelling and neurological complications. Diagnosis is with a high index of suspicion and imaging with duplex ultrasonography and CT angiography. Management options include observation, anticoagulation, ligation of the carotid artery with or without a bypass procedure, and arterial reconstruction.Early management with appropriate imaging and treatment to prevent significant mortality and morbidity is recommended. © 2008 Wiley Periodicals, Inc. Head Neck 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20851">
<title>Pulsatile tinnitus: A harbinger of a greater ill?</title>
<link>http://dx.doi.org/10.1002%2Fhed.20851</link>
<description><![CDATA[Pulsatile tinnitus is an uncommon otologic symptom, which may be the presenting complaint of a potentially devastating pathology. Understanding this manifestation as a possible symptom of a significant vascular abnormality is crucial to guide management and treatment.We describe a 38-year-old woman with sudden-onset right-sided pulsatile tinnitus. A right extracranial internal carotid artery (ICA) dissection was diagnosed with MRI/magnetic resonance angiography (MRA) and treated with anticoagulation. Follow-up MRI/MRA demonstrated complete resolution. Two months later, left-sided pulsatile tinnitus evolved. An MRI/MRA of the neck demonstrated left-sided extracranial ICA dissection. She was treated in a similar fashion and a repeat MRI/MRA demonstrated its resolution.Spontaneous extracranial ICA dissection may present with pulsatile tinnitus as the only symptom in 4% to 50% of patients. Subsequent evolution of a contralateral dissection is even more uncommon. Generally, treatment of this phenomenon is conservative utilizing anticoagulation or aspirin; however, surgical intervention may be necessary. © 2008 Wiley Periodicals, Inc. Head Neck 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20834">
<title>Cancer of the tonsil presenting as central nervous system metastasis: A case report</title>
<link>http://dx.doi.org/10.1002%2Fhed.20834</link>
<description><![CDATA[Metastases from tonsilar cancers are uncommon, usually found in the lung and less commonly in the bone, liver, and mediastinal sites. Only approximately 20% of patients die from distant metastasis. Central nervous system (CNS) metastases usually appear later in the course of the disease, with only 1% to 2% of patients developing metastasis involving the CNS in the course of their disease. Patients seen with symptomatic CNS lesions are rare.A case report is presented of a patient seen with signs and symptoms of CNS disease from an isolated CNS metastasis. The primary site was ultimately determined to be of tonsilar origin. The patient's treatment and outcome are discussed.Tonsilar cancers seen with signs and symptoms of CNS disease is a rare event. The benefit of aggressive treatment of isolated CNS metastasis from head and neck cancers will likely be gained from case reports because the incidence is quite low. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20822">
<title>Synovial sarcoma presenting as a parotid mass: Case report and review of literature</title>
<link>http://dx.doi.org/10.1002%2Fhed.20822</link>
<description><![CDATA[Synovial sarcoma is an unusual neoplasm of mesenchymal derivation, which is uncommon in the head and neck sites. In the parotid gland, it is most likely to be misdiagnosed as a myoepithelial, primary mesenchymal, or metastatic neoplasm.We report a case of synovial sarcoma in a young woman who was seen with temporomandibular joint symptoms with a 10-year history. A review of the literature was undertaken to highlight the radiologic and histologic features that help in diagnosis as well as the suggested therapeutic protocols most likely to ensure better survival.Radiologic and histologic studies of the parotid mass led to a diagnosis of synovial sarcoma. A total parotidectomy was performed, and the individual remains tumor free at 36months.Review of the literature suggests an aggressive long-term outcome for synovial sarcoma and advocates early diagnosis and radical surgical excision for a favorable prognosis. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20814">
<title>Lymphadenomatous carcinoma of the sublingual gland: Report of a first case in an unusual localization</title>
<link>http://dx.doi.org/10.1002%2Fhed.20814</link>
<description><![CDATA[Lymphadenomatous carcinoma of the salivary gland is a very rare tumor, which hitherto occurred exclusively in the parotid gland. This report describes a case of lymphadenomatous carcinoma of the sublingual gland, which is thought to be the first report of this special entity.A 36-year-old man was seen with slowly growing mass on his right floor of mouth. Upon surgical removal, the mass was well encapsulated. Microscopic examination revealed a biphasic appearance with islands of neoplastic epithelial cells presenting against a dense lymphoid stroma, while the epithelial compartment showed features of malignancy. During 30-months of close follow-up, there has not been any sign of local recurrence or metastasis.The clinical behavior, the age of the patient, and the sublingual localization differentiate this lesion from the sebaceous type, favoring lymphadenomatous carcinoma as a distinct clinical entity. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20812">
<title>Pseudogout: An unusual and forgotten metabolic sequela of parathyroidectomy</title>
<link>http://dx.doi.org/10.1002%2Fhed.20812</link>
<description><![CDATA[Parathyroidectomy is increasingly being performed by otolaryngology units. The well-known metabolic sequela is hypocalcaemia; it may be transient or permanent depending on presence and/or activity of any residual parathyroid tissue. A more unusual metabolic sequela of a parathyroidectomy is the development of pseudogout. We summarize the clinical presentation and pathophysiology of pseudogout following parathyroidectomy.We present a case of a 71-year-old woman who developed pseudogout following removal of a parathyroid adenoma.Although infrequent, pseudogout predominately occurs in the immediate postoperative period.We propose that otolaryngology units should be more aware of the unusual sequelae of pseudogout following parathyroidectomy; it can lead to a prompt referral and commencement of early treatment. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20801">
<title>Fibular free flaps in the management of osteomyelitis of the mandible</title>
<link>http://dx.doi.org/10.1002%2Fhed.20801</link>
<description><![CDATA[Fibular free flaps are an alternative method in the management of chronic osteomyelitis of the mandible without osteoradionecrosis.A prospective review of 2 cases of chronic osteomyelitis of the mandible managed with a fibular free flap was conducted. Patient satisfaction and aesthetic results were examined. Follow-up to 9 months was achieved and radiographic studies conducted. The current literature on the treatment of chronic osteomyelitis of the mandible and the use of free flaps in its management was reviewed.The 2 patients with chronic osteomyelitis of the mandible whose conservative management failed were effectively treated with the use of a fibular free flap reconstruction.Microvascular reconstruction with a fibular free flap should be considered as a treatment option in the management of chronic osteomyelitis of the mandible. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20809">
<title>Vallecular varix causing diagnostic confusion in hematemesis</title>
<link>http://dx.doi.org/10.1002%2Fhed.20809</link>
<description><![CDATA[Hematemesis is a common and dramatic presentation of upper gastrointestinal bleeding and is a source of significant morbidity and mortality. Common causes include peptic ulcer disease and varices. However, endoscopists need to be aware of other rare causes to avoid a delay in diagnosis, which may be potentially fatal.We present a case of vallecular varix causing recurrent hematemesis and successfully treated with sclerosant injection. We also review the literature regarding its pathogenesis and treatment.Vallecular varicosities are a rare cause of life-threatening bleeding from the aerodigestive tract. The area should be targeted early for evaluation especially in cases of bleeding of unknown origin. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20808">
<title>Nonresectable carotid body tumor: Hybrid surgical procedure to achieve complete and safe resection</title>
<link>http://dx.doi.org/10.1002%2Fhed.20808</link>
<description><![CDATA[Carotid body tumors of Shamblin class III without free internal carotid, between the tumor and skull base, are considered nonresectable. The objective of this work is to describe a surgical technique that combines traditional and endovascular strategies to achieve a safe surgical resection of the carotid body tumor of this class.A female patient with a nonresectable carotid body tumor underwent placement of an endoprosthesis going from the common carotid artery to the internal carotid beyond the skull base (to secure cerebral circulation) excluding the external carotid artery. Forty-five days later, the tumor was resected without vascular or cranial nerves injury, and bleeding amounted to 50 cm3. At 6 months, the patient is tumor free and asymptomatic.This is the first known reported case that has been successfully resolved by combining endovascular and traditional strategies. The endoprosthesis maintained cerebral circulation, which otherwisewould have been impossible; besides, the vascular supply from the external carotid artery was excluded leading to a decrease in tumor size and a recovery of the subadventitial dissection plane, allowing for a successful and safe tumor resection. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20806">
<title>Combined endovascular and surgical treatment of carotid body tumor in a patient with thoracic situs solitus</title>
<link>http://dx.doi.org/10.1002%2Fhed.20806</link>
<description><![CDATA[Chemodectomas of the head and neck are tumors that originate from the neural crest. The authors report a case of carotid body tumor with chronic hypoxia secondary to congenital cyanogenic cardiac malformation, radiologically and surgically treated.A 37-year-old woman presented 1-year history of a slow-growing right lateral-cervical swelling. Radiologic examination led to a suspicion of carotid body tumor. Her history revealed thoracic situs solitus and a complex congenital heart disease. She was hospitalized for a selective angiography of the cervical vessels. Twenty-four hours later, the tumor was completely removed under local anesthesia. One year later, there were no signs of recurrence, and the patient showed a correct hemodynamic compensation.The choice of surgical resection with selective preoperative embolization, which induced the obliteration of the feeder vessels, devascularizing the tumor and avoiding significant intraoperative bleeding, was successful. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
</item>

<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20803">
<title>Primary laryngeal natural killer/T-cell lymphoma - Report of a rare case</title>
<link>http://dx.doi.org/10.1002%2Fhed.20803</link>
<description><![CDATA[Natural killer (NK)/T-cell lymphoma involving the larynx is a rare entity, and its clinical picture has not been described.A 73-year-old man had a granulomatous tumor involving the larynx. Multiple biopsies over 1 year were needed to reach an accurate diagnosis of NK/T-cell lymphoma. This patient died of the disease despite the use of chemotherapy.To the best of our knowledge, this is the second case of primary laryngeal NK/T-cell that illustrates its clinical picture. In the early stage of the disease, this type of tumor can present as granulous tumor-like lesion without a definite destructive lesion. This tumor type should be kept in mind in tumors that are difficult to diagnose, especially in Asian populations. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
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<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20793">
<title>Vidian nerve schwannoma with middle cranial fossa extension resected via a maxillary swing approach</title>
<link>http://dx.doi.org/10.1002%2Fhed.20793</link>
<description><![CDATA[Vidian nerve schwannoma is an extremely rare type of facial nerve schwannoma. To the best of our knowledge, only 1 case has been reported.We report an additional case of vidian nerve schwannoma with middle cranial fossa extension in a 49-year-old Japanese woman. The surgical approaches for infratemporal fossa schwannomas are reviewed, and the maxillary swing approach we used is described.We adopted a maxillary swing approach combined with endonasal endoscopic techniques for the resection of the lesion. Gross total resection was achieved without sacrificing the trigeminal nerves or the facial motor nerves. The postoperative course was uneventful.Vidian nerve schwannoma is located in the retromaxillary space. It can grow silently until it involves the median skull base extensively. The maxillary swing approach was useful in this case. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
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<item rdf:about="http://dx.doi.org/10.1002%2Fhed.20773">
<title>Oral primary angiosarcoma of the lower lip mucosa: Report of a case in a 15-year-old boy</title>
<link>http://dx.doi.org/10.1002%2Fhed.20773</link>
<description><![CDATA[Angiosarcomas are rare soft tissue malignant tumors with dismal prognosis. Head and neck involvement is uncommon (5%) and usually affects the scalp or facial skin.We present the case of an inferior lip mucosal low-grade angiosarcoma in a 15-year-old boy treated exclusively with surgery. One and a half years after treatment, the patient was free of signs of recurrence. Prompt and accurate diagnosis with adequate imaging modalities and multidisciplinary treatment are crucial for optimal management of these neoplasms.Lip mucosal involvement is exceptional with only a few cases described in the literature, all in patients older than 60 years To our knowledge, this is the youngest patient ever reported. © 2008 Wiley Periodicals, Inc. Head Neck, 2008]]></description>
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