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<title>Psychopharmacology RSS : Gourt</title>
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<dc:date>2009-07-03T22:17+02:00
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<title>Improvement of risperidone-related tardive parkinsonism with a switch to aripiprazole.</title>
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	Related Articles
        Improvement of risperidone-related tardive parkinsonism with a switch to aripiprazole.
        Prog Neuropsychopharmacol Biol Psychiatry. 2009 Jun 26;
        Authors:  Chen CK, Wu JH
        
        PMID: 19563854 [PubMed - as supplied by publisher]
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<title>Isolation rearing induces social and emotional function abnormalities and alters glutamate and neurodevelopment related gene expression in rats.</title>
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	Related Articles
        Isolation rearing induces social and emotional function abnormalities and alters glutamate and neurodevelopment related gene expression in rats.
        Prog Neuropsychopharmacol Biol Psychiatry. 2009 Jun 26;
        Authors:  Zhao X, Sun L, Jia H, Meng Q, Wu S, Li N, He S
        Isolation rearing induces various cognitive abnormalities such as reversal learning deficits and reduced prepulse inhibition in rats. However, there are few reports in the literature on its effects on social and emotional functions. In the current study we aimed to address these issues and demonstrated that isolation rearing induced aggression and impaired social recognition, produced moderate anxiogenic effects in the elevated-plus maze, and resulted in hyperactivity in a novel open field. We also found NR2A, NR2B, PSD95 and SAP102 mRNA expression were significantly up-regulated in hippocampus while NR2B was down-regulated in medial prefrontal cortex in response to isolation rearing. This study advances the use of social isolation as an animal model for studying etiological mechanisms of various neuropsychiatric disorders.
        PMID: 19563853 [PubMed - as supplied by publisher]
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