[Articles] Antiglucocorticoids in psychiatry McIsaac, S. A., Westrin, A., Young, A. H. Tue, 30 Jun 2009 00:00:00 -0000
Significant evidence has accrued suggesting that the hypothalamic–pituitary–adrenal (HPA) axis plays a role in some psychiatric disorders. This article reviews the physiology of the HPA axis, evidence of dysfunction in this axis in psychiatric illnesses and the role that this dysfunction might play in pharmacological treatment resistance. Future therapeutic strategies that may potentially arise from these researches are briefly outlined.
[Articles] Targeting the HPA axis in major depression: does it work?: INVITED COMMENTARY ON... ANTIGLUCOCORTICOIDS IN PSYCHIATRY Claes, S. Tue, 30 Jun 2009 00:00:00 -0000
In the search for antidepressant drugs with enhanced efficacy, targeting the hypothalamic–pituitary–adrenal (HPA) axis is a valid strategy. This commentary critically summarises the evidence for the efficacy of antidepressant drugs targeting the HPA axis, and concludes that the available clinical trials do not support claims that this class of drugs is superior to existing treatments.
ECT practice and psychiatrists' attitudes towards ECT in the Chuvash Republic of the Russian Federation. Golenkov A, Ungvari GS, Gazdag G
ECT practice and psychiatrists' attitudes towards ECT in the Chuvash Republic of the Russian Federation.
Eur Psychiatry. 2009 Jun 30;
Authors: Golenkov A, Ungvari GS, Gazdag G
The practice of electroconvulsive therapy (ECT) and the attitudes of psychiatrists towards ECT in the Chuvash Republic are described. A significant proportion of Chuvash psychiatrists had a patchy knowledge about ECT and held negative attitudes towards the treatment. Enhancing the knowledge about ECT and changing negative attitudes will require persistent educational efforts.
PMID: 19574029 [PubMed - as supplied by publisher]
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