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<title>Ophthalmology RSS : Gourt</title>
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<dc:rights>Copyright 2007, Gourt.com</dc:rights>
<dc:date>2010-02-09T05:44+29:00
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<item rdf:about="http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_arizona/page_2.html">
<title>U.S. News and World Report-Ranked &#x91;America&#x92;s Top Hospitals&#x92;, Major Southwest Metro, #5224 :: Arizona :: Timeline Recruiting</title>
<link>http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_arizona/page_2.html</link>
<description><![CDATA[   Replete with natural wonders, history & culture, this region has been romancing people with its Old West charm for decades. Residents can also enjoy regional wine & cuisine, and explore a variety of ]]></description>
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<item rdf:about="http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_florida/page_4.html">
<title>Coastal Florida, Expanding Cataract Market, Live on the Gulf of Mexico, #5352 :: Florida :: Timeline Recruiting</title>
<link>http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_florida/page_4.html</link>
<description><![CDATA[   Let your entrepreneurial spirit explore an opportunity that has a reputation built on trust, loyalty, and customer satisfaction. The twenty-five years of hard work and continued success is the corner-stone ]]></description>
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<item rdf:about="http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_arizona/page_1.html">
<title>Pediatric OPH, University of Arizona in Metropolitan Tucson, #5482 :: Arizona :: Timeline Recruiting</title>
<link>http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_arizona/page_1.html</link>
<description><![CDATA[   We are a caring team of professionals, dedicated to the children in our community. Our Pediatric Ophthalmologists take a multidisciplinary team approach in providing medical care to our patients. Your ]]></description>
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<item rdf:about="http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_michigan/page_1.html">
<title>Detroit Suburb, $200K + potential, Partnership, #3430 :: Michigan :: Timeline Recruiting</title>
<link>http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_michigan/page_1.html</link>
<description><![CDATA[    Join a dedicated team looking for a partner. The groups founder will be retiring soon and they would like to bring on someone who has aspirations to become a partner after 2 years. The group has a ]]></description>
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<item rdf:about="http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_illinois/page_2.html">
<title>Ophthalmology Opportunity just East of Champaign, :: Illinois :: Enterprise Medical Service</title>
<link>http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_illinois/page_2.html</link>
<description><![CDATA[Well established multi-specialty group in college community in central Illinois in need of Ophthalmologist with Glaucoma fellowship.   Financial package to include attractive base guarantee, signing bonus, ]]></description>
</item>

<item rdf:about="http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_michigan/page_4.html">
<title>Eastern Michigan Seeks another Ophthalmologist :: Michigan :: Enterprise Medical Service</title>
<link>http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_michigan/page_4.html</link>
<description><![CDATA[Eastern Michigan community in need of additional general Ophthalmologist to join 2 in private practice.   Patient draw area covers 3 counties.   Financial package to include attractive income guarantee, ]]></description>
</item>

<item rdf:about="http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_missouri/page_1.html">
<title>Great Opportunity just outside of St. Louis :: Missouri :: Enterprise Medical Service</title>
<link>http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_missouri/page_1.html</link>
<description><![CDATA[Ophthalmologist needed to join VERY successful MSG practice outside St. Louis, MO.      Across the board, physicians in top 5% in earnings.    65+ docs in the group.  Physician owned and run Multi-Specialty ]]></description>
</item>

<item rdf:about="http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_florida/page_1.html">
<title>Beautiful Emerald Coast Region of Florida :: Florida :: Enterprise Medical Service</title>
<link>http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_florida/page_1.html</link>
<description><![CDATA[Emerald Coast region of Florida's panhandle in need of full time Ophthalmologist due to patient demand.  Hospital will assist in establishing of solo practice with income guarantee, signing bonus, marketing ]]></description>
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<item rdf:about="http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_indiana/page_1.html">
<title>Great Opportunity in Northern Indiana :: Indiana :: Enterprise Medical Service</title>
<link>http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_indiana/page_1.html</link>
<description><![CDATA[Ophthalmologist needed for MSG in northern Indiana.  This group has over 600 employees and more than 100 physicians and allied health providers. They are physician-owned and governed and have recently ]]></description>
</item>

<item rdf:about="http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_west_virginia/page_1.html">
<title>Northeastern West Virginia Area :: West Virginia :: Enterprise Medical Service</title>
<link>http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_west_virginia/page_1.html</link>
<description><![CDATA[Northeastern West Virginia in need of 3rdnd Ophthalmologist to join this private practice of 2 fellowship trained Ophthalmologists due to patient demand of over 150,000 draw area to include WV, MD, PA, ]]></description>
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<item rdf:about="http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_kansas/page_1.html">
<title>South Central KRC.1009.0813.03 :: Kansas :: Rural Health Education &#x26; Services</title>
<link>http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_kansas/page_1.html</link>
<description><![CDATA[ KRC.1009.0813.03 BC/BE certified Ophthalmologist needed for a 65 physician multispecialty group.  This well-established group is located conveniently near the admitting 200-bed hospital.  This is a fee ]]></description>
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<item rdf:about="http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_south_carolina/page_1.html">
<title>Northwest South Carolina :: South Carolina :: Enterprise Medical Service</title>
<link>http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_south_carolina/page_1.html</link>
<description><![CDATA[NW South Carolina Facility assisting private Ophthalmologist in hiring full time Ophthalmology partner to join him in new state-of-art medical clinic with electronic medical records.  Will be busy practice ]]></description>
</item>

<item rdf:about="http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_florida/page_2.html">
<title>West Coast Near Tampa :: Florida :: Enterprise Medical Service</title>
<link>http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_florida/page_2.html</link>
<description><![CDATA[Privately owned single specialty Ophthalmology group practice along western coastal Florida in need of hiring additional Ophthalmologist due to growth.  Will be joining 5 MDs, 5 Ods, call 1:5, must be ]]></description>
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<item rdf:about="http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_iowa/page_2.html">
<title>Northwestern Iowa :: Iowa :: Enterprise Medical Service</title>
<link>http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_iowa/page_2.html</link>
<description><![CDATA[Northwestern Iowa private Ophthalmology practice in need of 2nd  Ophthalmologist due to growth and patient demand.   Training in diseases and surgery of the vitreous and retina highly favored, but general ]]></description>
</item>

<item rdf:about="http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_texas/page_1.html">
<title>Northeast Texas :: Texas :: Enterprise Medical Service</title>
<link>http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_texas/page_1.html</link>
<description><![CDATA[Northeast Texas community in need of additional Ophthalmologist due to growth.  Financial package to include attractive salary, signing bonus, production bonuses, full benefits package including pension ]]></description>
</item>

<item rdf:about="http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_texas/page_2.html">
<title>Not Disclosed :: Texas :: Locum Medical Group</title>
<link>http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_texas/page_2.html</link>
<description><![CDATA[A facility north of Dallas, Texas seeks to hire an Ophthalmologist. Candidates must be either Board Certified or Board Eligible with an active Texas Medical license, DEA and DPS. Work Monday through Friday ]]></description>
</item>

<item rdf:about="http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_tennessee/page_1.html">
<title>Nashville, TN :: Tennessee :: Enterprise Medical Service</title>
<link>http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_tennessee/page_1.html</link>
<description><![CDATA[Need Ophthalmologist to join 1 other in Single Specialty practice.  General or retina Ophthalmologist is acceptable.  Must be boarded for consideration. Competitive salary based on academic ranking and ]]></description>
</item>

<item rdf:about="http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_california/page_1.html">
<title>Southern :: California :: Fidelis Partners</title>
<link>http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_california/page_1.html</link>
<description><![CDATA[ OPTHALMOLOGY-PEDIATRIC AND GLAUCOMA FOCUS SOUTHERN CALIFORNIA TURN-KEY PRACTICE-PATIENTS WAITING FOR YOU  This opportunity will not last!  Please contact me if you are interested in the following:   ]]></description>
</item>

<item rdf:about="http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_florida/page_3.html">
<title>Carlisle :: Florida :: Health Search, Inc.</title>
<link>http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_florida/page_3.html</link>
<description><![CDATA[ Ophthalmologist needed for to provide care & surgery for patients in both surgi-center and hospital settings.  Excellent facility and wonderful community in FL on the Gulf of Mexico. BE / BC candidates ]]></description>
</item>

<item rdf:about="http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_texas/page_3.html">
<title>McAllen :: Texas :: Eyear Optical</title>
<link>http://www.physemp.com/physician_jobs/perma_ophthalmology_jobs_in_texas/page_3.html</link>
<description><![CDATA[    Guaranteed Income, Negotiable Salary     Unique opportunity for physician seeking a low stress work environment/lifestyle.  OR, if you are considering retirement, are currently semi-retired or fully ]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/2009.408v1?rss=1">
<title>Laser Photocoagulation, Photodynamic Therapy, and Intravitreal Bevacizumab for the Treatment of Juxtafoveal Choroidal Neovascularization Secondary to Pathologic Myopia [Clinical Sciences]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/2009.408v1?rss=1</link>
<description><![CDATA[Objective&nbsp; To compare the effects on visual acuity of laser treatment (LT), photodynamic therapy (PDT) with verteporfin, and intravitreal bevacizumab treatment in patients with juxtafoveal choroidal neovascularization secondary to pathologic myopia.Methods&nbsp; This prospective randomized clinical investigation enrolled 54 patients, who were divided into 3 groups receiving PDT, LT, or intravitreal bevacizumab treatment. The anti&ndash;vascular endothelial growth factor group received 1.25 mg of intravitreal bevacizumab at baseline; retreatment was performed if persistent intraretinal or subretinal fluid evaluated on optical coherence tomography or if choroidal neovascularization progression was detected on fluorescein angiography. The PDT group received treatment following the Verteporfin in Photodynamic Therapy Study Group guidelines. The LT group was submitted to direct LT and received PDT treatment if subfoveal recurrence or progression was detected on fluorescein angiography. A change in best-corrected visual acuity was the primary outcome.Results&nbsp; The mean best-corrected visual acuity in the PDT group decreased from 0.52 logMAR (SD, 0.24 logMAR) at baseline to 0.72 logMAR (SD, 0.25 logMAR) at the end of the study (P&nbsp;=&nbsp;.002). The LT group showed substantial stabilization from mean baseline visual acuity (mean, 0.45 logMAR [SD, 0.27 logMAR]) to the 24-month (mean, 0.56 logMAR [SD, 0.34 logMAR) examination values. The mean best-corrected visual acuity in the anti&ndash;vascular endothelial growth factor group increased from 0.6 logMAR (SD, 0.3 logMAR) at baseline to 0.42 logMAR (SD, 0.35 logMAR) at the end of the study (P&nbsp;=&nbsp;.006).Conclusions&nbsp; Overall, bevacizumab treatment offers the best functional results during a 2-year follow-up. In view of the small size of the sample in this study and the relatively low frequency of juxtafoveal choroidal neovascularization secondary to pathologic myopia, a multicentric clinical trial is necessary to validate our results.Published online February 8, 2010 (doi:10.1001/archophthalmol.2009.408).]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/160?rss=1">
<title>About This Journal [About This Journal]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/160?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/165?rss=1">
<title>Fixed Combination of Latanoprost and Timolol vs Individual Components for Primary Open-Angle Glaucoma or Ocular Hypertension: A Randomized, Double-Masked Study [Clinical Trial]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/165?rss=1</link>
<description><![CDATA[
Objective&nbsp; To assess the efficacy and safety of fixed-combination latanoprost-timolol (FCLT) vs latanoprost or timolol monotherapy.
Methods&nbsp; This 12-week, randomized, double-masked, parallel-group study included patients with open-angle glaucoma or ocular hypertension treated with a &beta;-blocker and with baseline intraocular pressure (IOP) of 26 through 36 mm Hg. Following washout, eligible patients were randomized to once-daily FCLT in the evening, latanoprost in the evening, or timolol in the morning.
Main Outcome Measures&nbsp; Postbaseline IOP assessments at 8 am, 10 am, and 4 pm at weeks 2, 6, and 12; statistical superiority of FCLT for the 18 pairwise comparisons between FCLT and the 2 monotherapies, using analysis of variance.
Results&nbsp; All therapies resulted in significant IOP reductions from baseline. Pairwise comparisons favored FCLT at all time points. When the 18 comparisons were tested simultaneously, FCLT was statistically superior to latanoprost at 7 of 9 time points and at all 9 time points when compared with timolol. In addition, FCLT was associated with greater percentage reductions in diurnal IOP levels and a greater likelihood of achieving lower mean diurnal IOP levels. Diurnal IOP reductions of 30% or more from baseline to week 12 were achieved by 73.5%, 57.5%, and 32.8% of those treated with FCLT, latanoprost, and timolol, respectively (P&nbsp;=&nbsp;.007 for FCLT vs timolol; P&nbsp;&lt;&nbsp;.001 for FCLT vs latanoprost). All therapies were well tolerated.
Conclusions&nbsp; Fixed-combination latanoprost-timolol therapy is as safe and effective in lowering IOP in patients with either ocular hypertension or glaucoma as monotherapy with latanoprost or timolol. Combination therapy can be used to treat patients for whom monotherapy does not provide sufficient IOP reduction.
Application to Clinical Practice&nbsp; The simplicity, efficacy, and tolerability of FCLT contribute to its utility in clinical practice.
Trial Registration&nbsp; clinicaltrials.gov Identifier NCT00277498
]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/172?rss=1">
<title>Publishing Online Ahead of Print [Announcement]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/172?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/174?rss=1">
<title>Immunohistochemical Studies of Conjunctival Nevi and Melanomas [Clinical Sciences]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/174?rss=1</link>
<description><![CDATA[
Objective&nbsp; To evaluate the role of immunohistochemical methods in the diagnosis of benign and malignant conjunctival melanocytic proliferations.
Design&nbsp; Retrospective immunohistopathologic study.
Methods&nbsp; Paraffin-embedded tissue sections from 20 conjunctival nevi and 15 invasive melanomas were immunoreacted with antibodies against cellular antigens S-100 protein, MART-1, HMB-45, CD-45, and Ki-67 nuclear proliferation protein.
Results&nbsp; All nevi immunostained moderately to strongly for S-100 protein and MART-1. Results for HMB-45 were negative in the middle and lower subepithelial portions of 18 of 20 lesions; it was usually only weakly positive within the superficial junctional zone. Only 1 melanoma did not stain positively for S-100; MART-1 and HMB-45 were positive in all lesions at some level of intensity. Ki-67 positivity was restricted to the junctional zone of nevi and was diffuse in melanomas. The mean Ki-67 proliferation indices were 1.89% for the nevi and 17.3% for the melanomas. CD-45 can help to highlight lymphocytes that immunostain with Ki-67. Melanomas in situ and atypical primary acquired melanoses had more than twice the Ki-67 proliferation counts of intraepithelial junctional nevocytes (P&nbsp;&lt;&nbsp;.001) and more intense HMB-45 cytoplasmic staining than junctional zone nevocytes.
Conclusions&nbsp; S-100 and MART-1 were not useful in separating benign from malignant lesions. Results for nevus cells beneath the junctional zone were overwhelmingly negative for HMB-45 and Ki-67. Two nevi and all melanomatous nodules were positive for HMB-45 (P&nbsp;&lt;&nbsp;.001). A higher Ki-67 proliferation index convincingly separated melanomas from nevi (P&nbsp;&lt;&nbsp;.001). Immunostaining for HMB-45 and Ki-67 are valuable adjuncts to careful histopathologic evaluation in assessing benign and malignant conjunctival melanocytic tumors.
]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/184?rss=1">
<title>New Insights Into Changes in Corneal Thickness in Healthy Mountaineers During a Very-High-Altitude Climb to Mount Muztagh Ata [Clinical Sciences]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/184?rss=1</link>
<description><![CDATA[
Objective&nbsp; To investigate the effect of very high altitude and different ascent profiles on central corneal thickness (CCT).
Methods&nbsp; Twenty-eight healthy mountaineers were randomly assigned to 2 different ascent profiles during a medical research expedition to Mount Muztagh Ata (7546 m) in western China. Group 1 was allotted a shorter acclimatization time prior to ascent to 6265 m. The main outcome measure was CCT. Secondary outcome measures were oxygen saturation (SpO2) and symptom assessments of acute mountain sickness (cerebral acute mountain sickness score). Examinations were performed at 490, 4497, 5533, and 6265 m.
Results&nbsp; Central corneal thickness increased in both groups with increasing altitude and decreased after descent. In group 1 (with the shorter acclimatization), mean CCT increased from 537 to 572 &micro;m. Mean CCT in group 2 increased from 534 to 563 &micro;m (P&nbsp;=&nbsp;.048). The amount of decrease in SpO2 paralleled the increase in CCT. There was no significant decrease in visual acuity. There was a significant correlation between CCT and cerebral acute mountain sickness score when controlled for SpO2 and age.
Conclusions&nbsp; Corneal swelling during high-altitude climbs is promoted by low SpO2. Systemic delivery of oxygen to the anterior chamber seems to play a greater role in corneal oxygenation than previously thought. Adhering to a slower ascent profile results in less corneal edema. Visual acuity in healthy corneas is not adversely affected by edema at altitudes of up to 6300 m. Individuals with more acute mountain sickness&ndash;related symptoms had thicker corneas, possibly due to their higher overall susceptibility to hypoxia.
]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/189?rss=1">
<title>In Memoriam: Steven M. Podos, MD (1937-2009) [Obituary]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/189?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/190?rss=1">
<title>Efficacy of Sustained Topical Dorzolamide Therapy for Cystic Macular Lesions in Patients With X-Linked Retinoschisis [Clinical Sciences]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/190?rss=1</link>
<description><![CDATA[
Objective&nbsp; To determine the efficacy of sustained topical therapy with dorzolamide hydrochloride, 2%, on visual acuity and cystic macular lesions in patients with juvenile X-linked retinoschisis (XLRS).
Design&nbsp; Retrospective analysis.
Setting&nbsp; University hospital, tertiary care referral center.
Patients&nbsp; Twenty-nine eyes of 15 patients with XLRS receiving treatment with the topical dorzolamide formulation for 4 to 41 months were enrolled.
Main Outcome Measures&nbsp; Changes in visual acuity, cystic macular lesions, and central foveal zone thickness on optical coherence tomography during follow-up for the duration of treatment.
Results&nbsp; Among the 15 patients with XLRS, 20 eyes (69%) of 11 patients showed a positive response to treatment. Five of the 20 eyes (25%) in 3 of the 11 patients showed an initial response and a subsequent rebound of macular cysts. In 4 eyes (14%) of 3 patients, there was no response to treatment, but the macular cysts did not worsen compared with the baseline level. In 5 additional eyes (17%) of 4 patients, there was no response to treatment, and the macular cysts worsened when compared with the baseline level. Sixteen eyes (55%) of 12 patients had improvement in best-corrected visual acuity by at least 7 letters in at least 1 eye at the most recent follow-up visit. Seventeen eyes (59%) of 10 patients showed a reduction in the central foveal zone thickness in at least 1 eye when compared with the pretreatment level.
Conclusion&nbsp; Patients with XLRS have the potential to experience a beneficial effect from sustained treatment with dorzolamide, 2%.
]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/197?rss=1">
<title>Dr Thompson&#x27;s Eye Water [Ophthalmological Ephemera]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/197?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/198?rss=1">
<title>Relationship of Blood Pressure to Retinal Vessel Diameter in Type 1 Diabetes Mellitus [Clinical Sciences]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/198?rss=1</link>
<description><![CDATA[
Objective&nbsp; To examine the relationship of blood pressure (BP) and use of angiotensin-receptor blocker or angiotensin-converting enzyme inhibitor to retinal vessel diameter in normotensive, normoalbuminuric persons with type 1 diabetes mellitus.
Methods&nbsp; In a randomized, controlled clinical trial, clinic and 24-hour ambulatory BPs were measured in persons with type 1 diabetes mellitus and gradable fundus photographs both at baseline (n&nbsp;=&nbsp;147) and at 5-year follow-up (n&nbsp;=&nbsp;124). Retinal arteriole and venule diameters were measured by a computer-assisted technique. Individual arteriole and venule measurements were combined into summary indexes that reflect the average retinal arteriole (central retinal arteriole equivalent [CRAE]) and venule (central retinal venule equivalent [CRVE]) diameter of an eye, respectively.
Results&nbsp; While controlling for age, study site, glycosylated hemoglobin level, and ambulatory pulse rate, the daytime ambulatory systolic (&ndash;0.29-&micro;m effect per 1 mm Hg; P&nbsp;=&nbsp;.02), daytime ambulatory diastolic (&ndash;0.44-&micro;m effect per 1 mm Hg; P&nbsp;=&nbsp;.04), nighttime ambulatory systolic (&ndash;0.27-&micro;m effect per 1 mm Hg; P&nbsp;=&nbsp;.03), and 24-hour ambulatory systolic (&ndash;0.31-&micro;m effect per 1 mm Hg; P&nbsp;=&nbsp;.03) BPs were cross-sectionally associated with a smaller CRAE. While controlling for age, study site, glycosylated hemoglobin level, ambulatory pulse rate, and baseline CRAE, no BP measure was associated with a change in CRAE or CRVE during 5 years of follow-up. Treatment with losartan potassium or enalapril maleate was not associated with a statistically significant change in CRAE or CRVE.
Conclusion&nbsp; Angiotensin-converting enzyme inhibitor or angiotensin-receptor blocker therapy does not affect retinal arteriole or venule diameter in normotensive persons with type 1 diabetes mellitus.
Trial Registration&nbsp; clinicaltrials.gov Identifier: NCT00143949
]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/206?rss=1">
<title>Impact of Liver Transplantation on Transthyretin-Related Ocular Amyloidosis in Japanese Patients [Clinical Sciences]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/206?rss=1</link>
<description><![CDATA[
Objective&nbsp; To evaluate the long-term impact of liver transplantation on ocular manifestations of familial amyloid polyneuropathy (FAP) in Japanese patients.
Methods&nbsp; Medical records were retrospectively reviewed in a long-term follow-up study. Of 52 patients with FAP amyloidogenic transthyretin Val30Met, 22 patients underwent liver transplantation. We assessed ocular manifestations, including amyloid deposition at the pupillary border, pupillary border with irregularity, vitreous opacities, and glaucoma, in patients who underwent liver transplantation. In addition, we compared the clinical characteristics of vitreous opacities&mdash;the most common ocular manifestation of FAP&mdash;in patients who underwent liver transplantation and those who did not to determine the effect of transplantation on the progression of ocular amyloidosis.
Results&nbsp; Mean time after FAP onset was 10 years and after liver transplantation was 7 years in patients who underwent liver transplantation. All ocular manifestations increased with time after transplantation. Eight patients (36%) developed vitreous opacities and 4 patients (18%) developed glaucoma during follow-up. Mean time from FAP onset to vitreous opacities onset was significantly shorter in patients with early-onset disease who underwent liver transplantation than in those who did not.
Conclusions&nbsp; Patients with FAP who undergo liver transplantation continue to have a long-term risk of severe ocular manifestations, especially vitreous opacities and glaucoma, which can restrict their daily lives, even after liver transplantation.
]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/212?rss=1">
<title>Development of Choroidal Neovascularization in Rats With Advanced Intense Cyclic Light-Induced Retinal Degeneration [Laboratory Sciences]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/212?rss=1</link>
<description><![CDATA[
Objectives&nbsp; To study the progressive changes of intense cyclic light&ndash;induced retinal degeneration and to determine whether it results in choroidal neovascularization (CNV).
Methods&nbsp; Albino rats were exposed to 12 hours of 3000-lux cyclic light for 1, 3, or 6 months. Fundus examination, fundus photography, fluorescein and indocyanine green angiography, and optical coherence tomography were performed prior to euthanization. Light-exposed animals were euthanized after 1, 3, or 6 months for histopathological evaluation. Retinas were examined for the presence of 4-hydroxy-2-nonenal&ndash; and nitrotyrosine-modified proteins by immunofluorescence staining.
Results&nbsp; Long-term intense cyclic light exposure resulted in retinal degeneration with loss of the outer segments of photoreceptors and approximately two-thirds of the outer nuclear layer as well as development of subretinal pigment epithelium neovascularization after 1 month. Almost the entire outer nuclear layer was absent with the presence of CNV, which penetrated the Bruch membrane and extended into the outer retina after 3 months. Absence of the outer nuclear layer, multiple foci of CNV, retinal pigment epithelial fibrous metaplasia, and connective tissue bands containing blood vessels extending into the retina were observed after 6 months. All intense light&ndash;exposed animals showed an increased presence of 4-hydroxy-2-nonenal and nitrotyrosine staining. Optical coherence tomographic and angiographic studies confirmed retinal thinning and leakiness of the newly formed blood vessels.
Conclusions&nbsp; Our results suggest that albino rats develop progressive stages of retinal degeneration and CNV after long-term intense cyclic light exposure, allowing the detailed study of the pathogenesis and treatment of age-related macular degeneration.
Clinical Relevance&nbsp; The ability to study the progressive pathogenesis of age-related macular degeneration and CNV will provide detailed knowledge about the disease and aid in the development of target-specific therapy.
]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/223?rss=1">
<title>Expression of Vascular Endothelial Growth Factor in Retinoblastoma [Laboratory Sciences]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/223?rss=1</link>
<description><![CDATA[
Objectives&nbsp; To investigate the immunohistochemical expression of vascular endothelial growth factor (VEGF) and to determine its possible association with tumor differentiation status, optic nerve and/or choroidal invasion, anterior chamber invasion, vitreous seeding, and basophilic staining of the vascular walls.
Methods&nbsp; A retrospective study was performed to identify the expression of VEGF in 47 of 129 consecutive patients with retinoblastoma treated at the Ocular Pathology Laboratory of the Anatomy and Pathology Institute of the Central University of Venezuela in Caracas from January 1, 2000, through December 31, 2007.
Results&nbsp; A positive correlation between VEGF staining intensity and time of progression and mitotic and apoptotic indexes was observed. However, no correlation was found between VEGF expression and other prognostic factors in this malignant neoplasm, including tumor stage as assessed by the Grabowski and Abramson classification.
Conclusions&nbsp; Although the isolated characterization of VEGF in retinoblastoma is not grounds for this protein to be considered a prognostic factor, its association with mitotic and apoptotic indexes suggests it may play a role in the progression of this disease. Thus, therapeutic targeting of VEGF in retinoblastoma may be an effective strategy to reduce tumor progression.
]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/230?rss=1">
<title>Rate of Endophthalmitis After Cataract Surgery in Quebec, Canada, 1996-2005 [Epidemiology]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/230?rss=1</link>
<description><![CDATA[
Objective&nbsp; To estimate the annual incidence of endophthalmitis after cataract surgery from January 1, 1996, through December 31, 2005, in Quebec, Canada.
Methods&nbsp; Deidentified data were obtained from an outpatient physician billing database (Quebec State Control for Health Insurance [RAMQ]) with regard to all cataract surgical procedures performed from January 1, 1996, through December 31, 2005, in Quebec. For this cohort, records of an International Classification of Diseases, Ninth Revision (ICD-9) code for endophthalmitis during the same years were requested from 2 sources: the RAMQ outpatient database and an inpatient hospital discharge database (Maintenance and Exploitation of Data for the Study of Hospitalized Patients [MED-ECHO]). Endophthalmitis after cataract surgery was assumed if it occurred within 90 days of the surgery. Risk factors were examined using 2 tests and logistic regression.
Results&nbsp; After exclusions, 490&nbsp;690 cataract surgical procedures were performed from January 1, 1996, through December 31, 2005. A total of 754 cases of endophthalmitis occurred within 90 days after surgery for an overall incidence rate of 1.5 per 1000 surgical procedures (95% confidence interval [CI], 1.4-1.7). Factors associated with endophthalmitis included age of 85 years or older (odds ratio [OR],&nbsp;1.34; 95% CI, 1.06-1.70), male sex (1.44; 1.24-1.66), later year of surgery (0.94; 0.92-0.97), and region of cataract surgery, because regions 6 (2.21; 1.91-2.55) and 9 (4.00; 2.48-6.43) had higher rates compared with all other regions.
Conclusion&nbsp; Reasons that explain the apparent decrease in endophthalmitis, especially in 2005, should be explored and further research performed to understand why certain patients and regions have higher risks of endophthalmitis after cataract surgery.
]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/235?rss=1">
<title>Association Between the Use of Glaucoma Medications and Mortality [Socioeconomics and Health Services]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/235?rss=1</link>
<description><![CDATA[
Objective&nbsp; To evaluate the relationship between glaucoma medication use and death.
Methods&nbsp; This study uses longitudinal data from 2003 to 2007 on persons 40 years and older with glaucoma or suspected glaucoma enrolled in a large managed care network. Cox regression analysis was performed to estimate the hazard of death associated with the use of various glaucoma medication classes and combinations thereof. Multivariable models were adjusted for demographic characteristics and comorbid medical conditions.
Results&nbsp; Of 21&nbsp;506 participants with glaucoma or suspected glaucoma, 237 (1.1%) died during the study period. The use of any class of glaucoma medication was associated with a 74% reduced hazard of death (adjusted hazard ratio [HR], 0.26; 95% confidence interval [CI], 0.16-0.40) compared with no glaucoma medication use. This association was observed for use of a single agent alone, such as a topical &beta;-antagonist (0.44; 0.24-0.83) or a prostaglandin analogue (0.31; 0.18-0.54), and for use of different combinations of drug classes.
Conclusions&nbsp; After adjustment for potential confounding variables, the use of glaucoma medications was associated with a reduced likelihood of death in this large sample of US adults with glaucoma. Future investigations should explore this association further because these findings may have important clinical implications.
]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/241?rss=1">
<title>Harvesting Fresh Tumor Tissue From Enucleated Eyes: The 2008 Jack S. Guyton Lecture [Surgical Technique]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/241?rss=1</link>
<description><![CDATA[
There is an increasing need to obtain fresh tumor tissue and normal tissue for genetic studies and research following enucleation of an eye for uveal melanoma, retinoblastoma, and other lesions. A concern about doing this is that the globe will often collapse and lead to difficulties with gross and histopathologic interpretation. The technique reported herein is based on the creation of an opening in the sclera using an 8-mm corneal trephine followed by removal of tumor tissue. This method provides adequate tissue, preserves the spherical configuration of the eye, and allows for excellent histopathologic sections.
]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/244?rss=1">
<title>Intense Cyclic Light-Induced Retinal Degeneration in Rats [Editorial]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/244?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/246?rss=1">
<title>Moving Toward Information in the Blink of an Eye [Editorial]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/246?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/247?rss=1">
<title>Kindred With Prominent Corneal Nerves Associated With a Mutation in Codon 804 of RET on Chromosome 10q11 [Small Case Series]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/247?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/249?rss=1">
<title>Intravitreous Ranibizumab (Lucentis) for Radiation Maculopathy [Small Case Series]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/249?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/252?rss=1">
<title>September 2009 Archives Web Quiz Winner [Archives Web Quiz Winner]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/252?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/253?rss=1">
<title>Unusual Adaptive Optics Findings in a Patient With Bilateral Maculopathy [Research Letters]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/253?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/255?rss=1">
<title>Topical Treatment for Capillary Hemangioma of the Eyelid Using {beta}-Blocker Solution [Research Letters]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/255?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/256?rss=1">
<title>Propranolol for Isolated Orbital Infantile Hemangioma [Research Letters]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/256?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/258?rss=1">
<title>Ocular Involvement by Epstein-Barr Virus-Positive Diffuse Large B-Cell Lymphoma of the Elderly: A New Disease Entity in the World Health Organization Classification [Research Letters]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/258?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/259?rss=1">
<title>Severe Retinal Vascular Infarction After Photodynamic Therapy With Verteporfin Using the Standard Protocol [Research Letters]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/259?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/262?rss=1">
<title>Diabetic Macular Edema Following Panretinal Photocoagulation [Letters]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/262?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://archopht.ama-assn.org/cgi/content/short/128/2/262-a?rss=1">
<title>Diabetic Macular Edema Following Panretinal Photocoagulation--Reply [Letters]</title>
<link>http://archopht.ama-assn.org/cgi/content/short/128/2/262-a?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

</rdf:RDF>