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<title>Associations RSS : Gourt</title>
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<dc:rights>Copyright 2007, Gourt.com</dc:rights>
<dc:date>2010-02-07T04:43+21:00
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<item rdf:about="http://jama.ama-assn.org/cgi/content/short/2010.111v1?rss=1">
<title>Incomplete Financial Disclosure in: Herpes Zoster in the Age of Focused Immunosuppressive Therapy [Correction]</title>
<link>http://jama.ama-assn.org/cgi/content/short/2010.111v1?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/2010.110v1?rss=1">
<title>Incomplete Financial Disclosure in: A 70-Year-Old Woman With Shingles: Review of Herpes Zoster [Correction]</title>
<link>http://jama.ama-assn.org/cgi/content/short/2010.110v1?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/2010.109v1?rss=1">
<title>Incomplete Financial Disclosures in an Editorial, Clinical Crossroads, and Reply Letter Related to Herpes Zoster [Letters]</title>
<link>http://jama.ama-assn.org/cgi/content/short/2010.109v1?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/391?rss=1">
<title>This Week in JAMA [This Week in JAMA]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/391?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/423?rss=1">
<title>Relation Between Kidney Function, Proteinuria, and Adverse Outcomes [Original Contribution]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/423?rss=1</link>
<description><![CDATA[
Context&nbsp; The current staging system for chronic kidney disease is based primarily on estimated glomerular filtration rate (eGFR) with lower eGFR associated with higher risk of adverse outcomes. Although proteinuria is also associated with adverse outcomes, it is not used to refine risk estimates of adverse events in this current system.
Objective&nbsp; To determine the association between reduced GFR, proteinuria, and adverse clinical outcomes.
Design, Setting, and Participants&nbsp; Community-based cohort study with participants identified from a province-wide laboratory registry that includes eGFR and proteinuria measurements from Alberta, Canada, between 2002 and 2007. There were 920&nbsp;985 adults who had at least 1 outpatient serum creatinine measurement and who did not require renal replacement treatment at baseline. Proteinuria was assessed by urine dipstick or albumin-creatinine ratio (ACR).
Main Outcome Measures&nbsp; All-cause mortality, myocardial infarction, and progression to kidney failure.
Results&nbsp; The majority of individuals (89.1%) had an eGFR of 60 mL/min/1.73 m2 or greater. Over median follow-up of 35 months (range, 0-59 months), 27&nbsp;959 participants (3.0%) died. The fully adjusted rate of all-cause mortality was higher in study participants with lower eGFRs or heavier proteinuria. Adjusted mortality rates were more than 2-fold higher among individuals with heavy proteinuria measured by urine dipstick and eGFR of 60 mL/min/1.73 m2 or greater, as compared with those with eGFR of 45 to 59.9 mL/min/1.73 m2 and normal protein excretion (rate, 7.2 [95% CI, 6.6-7.8] vs 2.9 [95% CI, 2.7-3.0] per 1000 person-years, respectively; rate ratio, 2.5 [95% CI, 2.3-2.7]). Similar results were observed when proteinuria was measured by ACR (15.9 [95% CI, 14.0-18.1] and 7.0 [95% CI, 6.4-7.6] per 1000 person-years for heavy and absent proteinuria, respectively; rate ratio, 2.3 [95% CI, 2.0-2.6]) and for the outcomes of hospitalization with acute myocardial infarction, end-stage renal disease, and doubling of serum creatinine level.
Conclusion&nbsp; The risks of mortality, myocardial infarction, and progression to kidney failure associated with a given level of eGFR are independently increased in patients with higher levels of proteinuria.
]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/430?rss=1">
<title>Brainstem Serotonergic Deficiency in Sudden Infant Death Syndrome [Preliminary Communication]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/430?rss=1</link>
<description><![CDATA[
Context&nbsp; Sudden infant death syndrome (SIDS) is postulated to result from abnormalities in brainstem control of autonomic function and breathing during a critical developmental period. Abnormalities of serotonin (5-hydroxytryptamine [5-HT]) receptor binding in regions of the medulla oblongata involved in this control have been reported in infants dying from SIDS.
Objective&nbsp; To test the hypothesis that 5-HT receptor abnormalities in infants dying from SIDS are associated with decreased tissue levels of 5-HT, its key biosynthetic enzyme (tryptophan hydroxylase [TPH2]), or both.
Design, Setting, and Participants&nbsp; Autopsy study conducted to analyze levels of 5-HT and its metabolite, 5-hydroxyindoleacetic acid (5-HIAA); levels of TPH2; and 5-HT1A receptor binding. The data set was accrued between 2004 and 2008 and consisted of 41 infants dying from SIDS (cases), 7 infants with acute death from known causes (controls), and 5 hospitalized infants with chronic hypoxia-ischemia.
Main Outcome Measures&nbsp; Serotonin and metabolite tissue levels in the raph&eacute; obscurus and paragigantocellularis lateralis (PGCL); TPH2 levels in the raph&eacute; obscurus; and 5-HT1A binding density in 5 medullary nuclei that contain 5-HT neurons and 5 medullary nuclei that receive 5-HT projections.
Results&nbsp; Serotonin levels were 26% lower in SIDS cases (n&nbsp;=&nbsp;35) compared with age-adjusted controls (n&nbsp;=&nbsp;5) in the raph&eacute; obscurus (55.4 [95% confidence interval {CI}, 47.2-63.6] vs 75.5 [95% CI, 54.2-96.8] pmol/mg protein, P&nbsp;=&nbsp;.05) and the PGCL (31.4 [95% CI, 23.7-39.0] vs 40.0 [95% CI, 20.1-60.0] pmol/mg protein, P&nbsp;=&nbsp;.04). There was no evidence of excessive 5-HT degradation assessed by 5-HIAA levels, 5-HIAA:5-HT ratio, or both. In the raph&eacute; obscurus, TPH2 levels were 22% lower in the SIDS cases (n&nbsp;=&nbsp;34) compared with controls (n&nbsp;=&nbsp;5) (151.2% of standard [95% CI, 137.5%-165.0%] vs 193.9% [95% CI, 158.6%-229.2%], P&nbsp;=&nbsp;.03). 5-HT1A receptor binding was 29% to 55% lower in 3 medullary nuclei that receive 5-HT projections. In 4 nuclei, 3 of which contain 5-HT neurons, there was a decrease with age in 5-HT1A receptor binding in the SIDS cases but no change in the controls (age&nbsp;x&nbsp;diagnosis interaction). The profile of 5-HT and TPH2 abnormalities differed significantly between the SIDS and hospitalized groups (5-HT in the raph&eacute; obscurus: 55.4 [95% CI, 47.2-63.6] vs 85.6 [95% CI, 61.8-109.4] pmol/mg protein, P&nbsp;=&nbsp;.02; 5-HT in the PGCL: 31.4 [95% CI, 23.7-39.0] vs 71.1 [95% CI, 49.0-93.2] pmol/mg protein, P&nbsp;=&nbsp;.002; TPH2 in the raph&eacute; obscurus: 151.2% [95% CI, 137.5%-165.0%] vs 102.6% [95% CI, 58.7%-146.4%], P&nbsp;=&nbsp;.04).
Conclusion&nbsp; Compared with controls, SIDS was associated with lower 5-HT and TPH2 levels, consistent with a disorder of medullary 5-HT deficiency.
]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/438?rss=1">
<title>Risk of Deep Vein Thrombosis Following a Single Negative Whole-Leg Compression Ultrasound: A Systematic Review and Meta-analysis [Clinical Review]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/438?rss=1</link>
<description><![CDATA[
Context&nbsp; In patients with suspected lower extremity deep vein thrombosis (DVT), compression ultrasound (CUS) is typically the initial test to confirm or exclude DVT. Patients with an initial negative CUS result often require repeat CUS after 5 to 7 days. Whole-leg CUS may exclude proximal and distal DVT in a single evaluation.
Objective&nbsp; To determine the risk of venous thromboembolism after withholding anticoagulation in patients with suspected lower extremity DVT following a single negative whole-leg CUS result.
Data Sources&nbsp; MEDLINE, EMBASE, CINAHL, LILACS, Cochrane, and Health Technology Assessments databases were searched for articles published from January 1970 through November 2009. Supplemental searches were performed of Internet resources, reference lists, and by contacting content experts.
Study Selection&nbsp; Included studies were randomized controlled trials and prospective cohort studies of patients with suspected DVT and a negative whole-leg CUS result who did not receive anticoagulant therapy, and were followed up at least 90 days for venous thromboembolism events.
Data Extraction&nbsp; Two authors independently reviewed and extracted data regarding a single positive or negative whole-leg CUS result, occurrence of venous thromboembolism during follow-up, and study quality.
Results&nbsp; Seven studies were included totaling 4731 patients with negative whole-leg CUS examinations who did not receive anticoagulation. Of these, up to 647 patients (13.7%) had active cancer and up to 725 patients (15.3%) recently underwent a major surgery. Most participants were identified from an ambulatory setting. Venous thromboembolism or suspected venous thromboembolism&ndash;related death occurred in 34 patients (0.7%), including 11 patients with distal DVT (32.4%); 7 patients with proximal DVT (20.6%); 7 patients with nonfatal pulmonary emboli (20.6%); and 9 patients (26.5%) who died, possibly related to venous thromboembolism. Using a random-effects model with inverse variance weighting, the combined venous thromboembolism event rate at 3 months was 0.57% (95% confidence interval, 0.25%-0.89%).
Conclusion&nbsp; Withholding anticoagulation following a single negative whole-leg CUS result was associated with a low risk of venous thromboembolism during 3-month follow-up.
]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/446?rss=1">
<title>Does Insulin Therapy Promote, Reduce, or Have a Neutral Effect on Cancers? [Commentary]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/446?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/448?rss=1">
<title>Reducing Dietary Sodium: The Case for Caution [Commentary]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/448?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/450?rss=1">
<title>Safe Electronic Health Record Use Requires a Comprehensive Monitoring and Evaluation Framework [Commentary]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/450?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/452?rss=1">
<title>Electronic Health Records in the Age of Social Networks and Global Telecommunications [Commentary]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/452?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/454?rss=1">
<title>Evidence-Based Medicine Requires Appropriate Clinical Context [Editorial]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/454?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/455?rss=1">
<title>Caring for an Aging Population: Call for Papers [Editorial]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/455?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/418?rss=1">
<title>Procalcitonin-Based Guidelines and Lower Respiratory Tract Infections [Letters]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/418?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/418-a?rss=1">
<title>Procalcitonin-Based Guidelines and Lower Respiratory Tract Infections [Letters]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/418-a?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/419?rss=1">
<title>Procalcitonin-Based Guidelines and Lower Respiratory Tract Infections--Reply [Letters]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/419?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/420?rss=1">
<title>Diabetic Polyneuropathy and Glucose Control [Letters]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/420?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/420-a?rss=1">
<title>Diabetic Polyneuropathy and Glucose Control--Reply [Letters]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/420-a?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/421?rss=1">
<title>Updated Analysis of Gene Variants Associated With Deep Vein Thrombosis [Research Letters]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/421?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/403?rss=1">
<title>Use of Earth-Observing Satellite Data Helps Predict, Prevent Disease Outbreaks [Medical News &#x26; Perspectives]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/403?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/405?rss=1">
<title>New Findings Challenge Thinking About Anemia, Iron Deficiency, and Heart Risk [Medical News &#x26; Perspectives]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/405?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/406?rss=1">
<title>Epilepsy Experts Focus on Treatment Gaps [Medical News &#x26; Perspectives]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/406?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/412?rss=1">
<title>Office of Inspector General: CDC Lax in Policing Advisors&#x27; Conflicts of Interest [Medical News &#x26; Perspectives]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/412?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/413?rss=1">
<title>Imported Case of Marburg Hemorrhagic Fever--Colorado, 2008 [From the Centers for Disease Control and Prevention]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/413?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/415?rss=1">
<title>Idiopathic Granulomatous Mastitis in Hispanic Women--Indiana, 2006-2008 [From the Centers for Disease Control and Prevention]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/415?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/395?rss=1">
<title>Star Shaped Islamic Tiles With Cross Shaped Infill [The Cover]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/395?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/397?rss=1">
<title>An Oath to My Grandfather [A Piece of My Mind]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/397?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/396?rss=1">
<title>Sunday Mournings [Poetry and Medicine]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/396?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/461?rss=1">
<title>IMAGINATION AND IDEALISM IN THE MEDICAL SCIENCES [JAMA 100 Years Ago]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/461?rss=1</link>
<description><![CDATA[ ]]></description>
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<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/457?rss=1">
<title>Atlas of Interventional Pain Management [Book and Media Reviews]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/457?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/458?rss=1">
<title>Radiology Education: The Scholarship of Teaching and Learning [Book and Media Reviews]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/458?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/459?rss=1">
<title>Faith and Health: Religion, Science, and Public Policy [Book and Media Reviews]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/459?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/459-a?rss=1">
<title>Compartments: How the Brightest, Best Trained, and Most Caring People Can Make Judgments That Are Completely and Utterly Wrong [Book and Media Reviews]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/459-a?rss=1</link>
<description><![CDATA[ ]]></description>
</item>

<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/422?rss=1">
<title>Omitted Figure Reference and Sentence in: Propagation of Human Spermatogonial Stem Cells In Vitro [Correction]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/422?rss=1</link>
<description><![CDATA[ ]]></description>
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<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/422-a?rss=1">
<title>Financial Disclosure Source Incorrectly Named in: Clinical Care in the Aging Century: Announcing &#x27;Care of the Aging Patient: From Evidence to Action&#x27; [Correction]</title>
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<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/422-b?rss=1">
<title>Incorrect Number in Abstract in: Strength of Study Evidence Examined by the FDA in Premarket Approval of Cardiovascular Devices [Correction]</title>
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<description><![CDATA[ ]]></description>
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<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/470?rss=1">
<title>Proteinuria [JAMA Patient Page]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/470?rss=1</link>
<description><![CDATA[ ]]></description>
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<item rdf:about="http://jama.ama-assn.org/cgi/content/short/303/5/393?rss=1">
<title>About This Journal [About This Journal]</title>
<link>http://jama.ama-assn.org/cgi/content/short/303/5/393?rss=1</link>
<description><![CDATA[ ]]></description>
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