A journal (through French from late Latin diurnalis, daily) has several related meanings:

• a daily record of events or business; a private journal is usually referred to as a diary.
• a newspaper or other periodical, in the literal sense of one published each day;
• however, some publications issued at stated intervals, such as a magazine or the record of the transactions of society such as a scientific journal or academic journals in general, are called a journal. Journal, then, is sometimes used as a synonym for "magazine".

The word "journalist" for one whose business is writing for the public press has been in use since the end of the 17th century.

"Journal" is also applied to the record, day by day, of the business and proceedings of a public body:

• The journals of the British Houses of Parliament contain an official record of the business transacted day by day in either house. The record does not take note of speeches, though some of the earlier volumes contain references to them. The journals are a lengthened account written from the "Votes and Proceedings" (in the House of Lords called "Minutes of Proceedings"), made day by day by the Clerks at the Table, and printed on the responsibility of the Clerk of the House. In the Commons the Votes and Proceedings, but not the Journal, bear the Speaker's signature in fulfilment of a former order that he should "peruse" them before publication. The journals of the British House of Commons begin in the first year of the reign of Edward VI in 1547, and are complete, except for a short interval under Elizabeth I. Those of the House of Lords date from the first year of Henry VIII in 1509. Before that date the proceedings in parliament were entered in the rolls of parliament, which extend from 1278 to 1503. The journals of the Lords are "records" in the judicial sense, those of the Commons are not (see Erskine May, Parliamentary Practice, 1906, pp. 201-202).
• Section 5 of Article I of the United States Constitution requires the Congress of the United States to keep a journal of its proceedings. This journal, the Congressional Record is published by the Government Printing Office.

Journals of this sort are also often referred to as minutes.

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Hematological Oncology

Silibinin can induce differentiation as well as enhance vitamin D3-induced differentiation of human AML cells ex vivo and regulates the levels of differentiation-related transcription factors
Jing Zhang, Jonathan S Harrison, Milan Uskokovic, Michael Danilenko, George P Studzinski Wed, 28 Oct 2009 04:28:00 -0000
Induction of terminal differentiation is a conceptually attractive approach for the therapy of neoplastic diseases. Although vitamin D derivatives (deltanoids) can induce differentiation of AML cells in vitro, so far deltanoids have not been successfully brought to the clinic, due to the likelihood of life-threatening hypercalcemia. Here, we incubated freshly obtained blood cells from patients with AML with a plant antioxidant (PAOx), silibinin (SIL), alone or together with a deltanoid. Twenty patients with AML (all subtypes except M3) were available for this study, and in 14 (70%), SIL (60 µM) either induced differentiation ex vivo, or enhanced differentiation induced by deltanoids, or both. Interestingly, SIL acting alone induced differentiation only in cases in which chromosome aberrations could not be detected. In eleven samples sufficient material was available for a limited analysis of the underlying events. Quantitative RT-PCR showed that differentiation markers were upregulated at the mRNA level by both SIL and deltanoids, suggesting that intracellular signaling pathways upstream of transcription factors (TFs) were activated by these agents. Western analysis for proteins which function as TFs in deltanoid-induced monocytic differentiation, such as members of Jun and C/EBP families, surprisingly demonstrated that SIL upregulated all these TFs in the cases tested. This suggests that although the presence of SIL may not always be sufficient to induce differentiation, it can serve as a differentiation enabling factor for blasts obtained from a large proportion of patients with AML. Thus, SIL/deltanoid combinations warrant further consideration as preventive/therapeutic regimens in human leukaemia. Copyright © 2009 John Wiley & Sons, Ltd.

Annals of Hematology

Splenic artery pseudoaneurysm with rupture by transformed splenic marginal zone B cell lymphoma
Tue, 03 Nov 2009 21:11:50 -0000
Splenic artery pseudoaneurysm with rupture by transformed splenic marginal zone B cell lymphoma Content Type Journal ArticleCategory Letter to the EditorDOI 10.1007/s00277-009-0851-2Authors Yu-Chung Huang, Taipei Veterans General Hospital Division of Hematology & Oncology, Department of Medicine No. 201, Sec. 2, Shipai Rd Taipei 112 TaiwanZhi-Yi Xie, Taipei Veterans General Hospital Division of Hematology & Oncology, Department of Medicine No. 201, Sec. 2, Shipai Rd Taipei 112 TaiwanHsiou-Shan Tseng, Taipei Veterans General Hospital Department of Radiology No. 201, Sec. 2, Shipai Rd Taipei 112 TaiwanChing-Feng Yang, Taipei Veterans General Hospital Department of Pathology No. 201, Sec. 2, Shipai Rd Taipei 112 TaiwanLiang-Tsai Hsiao, Taipei Veterans General Hospital Division of Hematology & Oncology, Department of Medicine No. 201, Sec. 2, Shipai Rd Taipei 112 Taiwan Journal Annals of HematologyOnline ISSN 1432-0584Print ISSN 0939-5555

American Journal of Hematology

On being metachromatic: Mystique and misunderstanding in mastocytosis
Jason Gotlib Fri, 23 Oct 2009 14:51:00 -0000
No abstract.

Pediatric Hematology and Oncology: Articles recently published in

CLINICAL PROFILE AND HOME MANAGEMENT OF SICKLE CELL-RELATED PAIN: The Enugu (Nigeria) Experience
Ikefuna, Anthony N.Emodi, Ifeoma J.Ocheni, Sunday Wed, 01 Jul 2009 00:00:00 -0000


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