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Pemphigus is an autoimmune disorder that causes blistering and raw sores on skin and mucous membranes. As with other autoimmune disorders, it is caused when the body's defenses mistake its own tissues as foreign, and attack the cells. Pemphigus is derived from the Greek word pemphix meaning bubble or blister.

Types


There are three types of pemphigus which vary in severity: pemphigus vulgaris, pemphigus foliaceus, and paraneoplastic pemphigus.

  • The most common form of the disorder is pemphigus vulgaris (ICD-10 L10.0). It occurs when antibodies attack Desmoglein 3, a protein that keeps cells bound together. Thus, cells simply fall apart, causing skin to slough off. Although pemphigus vulgaris may occur at any age, it is quite rare in children, and most common in the middle aged and elderly. Sores often originate in the mouth, making eating difficult and uncomfortable. Pemphigus vulgaris often affects people between the ages of 40-60, and mainly of Jewish or Mediterranean descent. Some patients are associated with myasthenia gravis,but it's unusual.

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Auto Immune
Skin Disorders :: Conditions and Diseases

 
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Pemphigus Vulgaris (pv) Has Anyone Gone Through It And Lived A Normal Active Life? http://bit.ly/7QFpWO
lalivenews (Seth Donaldson) Thu, 17 Dec 2009 17:15:21 -0000
Pemphigus Vulgaris (pv) Has Anyone Gone Through It And Lived A Normal Active Life? http://bit.ly/7QFpWO
myasthenia gravis, pemphigus, pemphigoid, goodpasture;s, coeliac, hepatitis, PBC, adrenalitis, SLE, sjogren, scleroderma, RA, polymyositis
Danielf90 (Daniel Sommer) Thu, 10 Dec 2009 19:05:36 -0000
myasthenia gravis, pemphigus, pemphigoid, goodpasture;s, coeliac, hepatitis, PBC, adrenalitis, SLE, sjogren, scleroderma, RA, polymyositis
[Basic and clinical research on paraneoplastic pemphigus]: - http://tinyurl.com/ykpe5yx
research_papers (qasim) Thu, 10 Dec 2009 08:08:31 -0000
[Basic and clinical research on paraneoplastic pemphigus]: - http://tinyurl.com/ykpe5yx

 
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International Pemphigus Foundation - Includes information about the condition, the organisation, plus support groups.
Meta Description: [ The International Pemphigus Foundation provides information about the autoimmune skin disorders known as pemphigus and pemphigoid while also offering advice and support to sufferers and caregivers. ]

Pemphigus - Information on the types and treatments.

Pemphigus - Background information, traditional treatments and natural medicine, plus the author's personal account.

Pemphigus Research - Describes this autoimmune blistering disease and outlines ongoing research by John Hopkins University.

Pemphigus Vulgaris - An article explaining the seriousness of the condition.

The Pemphigus and Pemphigoid Society - Find information about PPS, publications, an online support group, articles and a medical glossary.
Meta Description: [ The Pemphigus & Pemphigoid Society provides the most comprehensive collection of information about pemphigus and pemphigoid, two rare autoimmune blistering diseases. This homepage is an index of this information. As a 501(c)(3) nonprofit foundation, 100% of donations, gifts and grants go to help ... ]

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