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Mucous membrane pemphigoid is an autoimmune reaction that occurs at the level of the basement membrane. Commonly affects gingiva. Desquamating/blistering disease in which epithelial separation takes place at the level of the basement membrane.

Antibodies (IgG) precipitates complement (C3) in the lamina lucida of the BM. Circulating auto-antibodies to BP-1 antigen (located in hemidesmosome). 50% have BP-2. Positive Nikolsky sign. IgG, C3 deposition at BM creating smooth line in immunoflourescent analysis.

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Rituximab offers hope: Treatment provides steroid-sparing response in refractory bullous pemphigoid http://bit.ly/4LO1HY #dermatology
DermTimesNow (Dermatology Times) Sat, 12 Dec 2009 23:26:56 -0000
Rituximab offers hope: Treatment provides steroid-sparing response in refractory bullous pemphigoid http://bit.ly/4LO1HY #dermatology
myasthenia gravis, pemphigus, pemphigoid, goodpasture;s, coeliac, hepatitis, PBC, adrenalitis, SLE, sjogren, scleroderma, RA, polymyositis
Danielf90 (Daniel Sommer) Thu, 10 Dec 2009 19:05:36 -0000
myasthenia gravis, pemphigus, pemphigoid, goodpasture;s, coeliac, hepatitis, PBC, adrenalitis, SLE, sjogren, scleroderma, RA, polymyositis
Allergy/Immunology Potential role of interleukin-17 in the pathogenesis of bullous pemphigoid.. http://bit.ly/4Jgluk
MDLinx (Sandeep Pulim MD) Wed, 09 Dec 2009 13:07:12 -0000
Allergy/Immunology Potential role of interleukin-17 in the pathogenesis of bullous pemphigoid.. http://bit.ly/4Jgluk
Newest Dermatology Nursing includes these articles:Bullous Pemphigoid, Perioral Dermatitis, and What's Your Assessment. http://tr.im/newDNJ
DermNursing (Dermatology Nursing) Tue, 08 Dec 2009 14:58:28 -0000
Newest Dermatology Nursing includes these articles:Bullous Pemphigoid, Perioral Dermatitis, and What's Your Assessment. http://tr.im/newDNJ
Bullous pemphigoid and pemphigus vulgaris Read more at: http://ping.fm/Ml8bl
healourskin (IPPF) Mon, 07 Dec 2009 17:40:06 -0000
Bullous pemphigoid and pemphigus vulgaris Read more at: http://ping.fm/Ml8bl

 
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