Pellagra is a vitamin deficiency disease caused by dietary lack of niacin and protein, especially proteins containing the essential amino acid tryptophan. Because tryptophan can be converted into niacin, foods with tryptophan but without niacin, such as milk, prevent pellagra. However, tryptophan is also a precursor for protein, so if there is a deficiency in niacin and protein, then tryptophan production will be diverted into protein, leading to a deficiency of niacin.
Some sources also claim a relationship between lysine and pellagra, but this position does not have nearly as much support.

Dr. Joseph Goldberger and the War on Pellagra - Informative article on the history of this disorder.
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Pellagra - A discussion on niacin and how its absorbed, deficiencies, diet recommendations, food sources and toxicity.
Meta Description: [ Pellagra, the classic niacin deficiency disease,is characterized by bilateral dermatitis in sun exposed areas,
glossitis, diarrhea, and dementia. ]
Pellagra - Find information on this disorder, its alternate names and symptoms.
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