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Hyperlipidemia, hyperlipoproteinemia or dyslipidemia is the presence of elevated or abnormal levels of lipids and/or lipoproteins in the blood. Lipids (fatty molecules) are transported in a protein capsule, and the density of the lipids and type of protein determines the fate of the particle and its influence on metabolism.

Lipid and lipoprotein abnormalities are extremely common in the general population, and are regarded as a highly modifiable risk factor for cardiovascular disease due to the influence of cholesterol, one of the most clinically relevant lipid substances, on atherosclerosis. In addition, some forms may predispose to acute pancreatitis.

Classification


Hyperlipidemias are classified according to the Fredrickson classification which is based on the pattern of lipoproteins on electrophoresis or ultracentrifugation.Frederickson DS, Lee RS. A system for phenotyping hyperlipidemia. Circulation 1965;31:321-7. PMID 14262568. It was later adopted by the World Health Organization (WHO). It does not directly account for HDL, and it does not distinguish among the different genes that may be partially responsible for some of these conditions. It remains a popular system of classification, but is considered dated by many.

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Hyperlipidemia - An overview, risk of coronary heart disease, testing-know your numbers, prevention and treatment.
Meta Description: [ At Advanced Cardiac Specialists, we believe that how we care determines who we are. That is why a dedicated team of physicians and staff works round the clock to put our adage into practice every single day: Leading-edge medicine in everyday care ]

Hyperlipidemia - A four article symposium discussing the causes, treatments, and risks of high cholesterol.

Hyperlipidemia in Children - American Heart Association looks at the atherosclerotic process which begins in childhood and is affected by high blood cholesterol levels. Some things to watch for.

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