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The motor neurone diseases (MND) are a group of progressive neurological disorders that destroy motor neurones, the cells that control voluntary muscle activity such as speaking, walking, breathing, and swallowing. Amyotrophic lateral sclerosis (ALS), sometimes called Lou Gehrig's disease, progressive muscular atrophy (PMA), spinal muscular atrophy (SMA), progressive or pseudo-bulbar palsy (PBP) and primary lateral sclerosis (PLS) are all forms of motor neurone disease.

Terminology


In this article, MND refers to a group of diseases which affect the motor neurones. In the United States, the term ALS is more commonly used, where it is also known as Lou Gehrig's disease, after the baseball player. Although previously described by other neurologists of the 19th century, it was Jean-Martin Charcot, a French neurologist, who suggested grouping together a number of disparate conditions all affecting the lateral horn of the spinal cord in 1869. In France the disease is sometimes known as Maladie de Charcot (Charcot's disease), although it may also be referred to by the direct translation of ALS, Sclerose Laterale Amyotrophique (SLA). To help prevent confusion, the annual scientific research conference dedicated to the study of MND is called the International ALS/MND Symposium.

Signs and symptoms


Neurological examination presents specific signs associated with upper and lower motor neurone degeneration. Signs of upper motor neurone damage include spasticity, brisk reflexes and the Babinski sign. Signs of lower motor neurone damage include weakness and muscle atrophy.

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New Article from Journal of NeuroScience Activities of daily living in motor neuron disease... http://t.co/NV3MWwDj
ALSAssistiveTec (Alisa Brownlee ) Fri, 27 Jan 2012 14:20:00 -0000
New Article from Journal of NeuroScience Activities of daily living in motor neuron disease... http://t.co/NV3MWwDj
Heard this? RTÉ's Colm Murray: Fighting motor neuron disease with courage, dignity and class: The first... http://t.co/nsqa1YeT - Nancee
NanceeDrewe (Nancee Drewe) Fri, 27 Jan 2012 13:52:56 -0000
Heard this? RTÉ's Colm Murray: Fighting motor neuron disease with courage, dignity and class: The first... http://t.co/nsqa1YeT - Nancee
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Amyotrophic Lateral Sclerosis Fact Sheet - A fact sheet about symptoms, diagnosis, treatment, and research on ALS, Motor Neuron Disease, or Lou Gehrig's Disease from the National Institute of Neurological Disorders and Stroke.

Amyotrophic Lateral Sclerosis: Lou Gehrig's Disease - Good article by the American Academy of Family Physicians.

Kennedy's Disease Association - Information about Kennedy's Disease, Symptoms, Chat, Forum.

Monomelic Amyotrophy - Information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS).
Meta Description: [ Monomelic amyotrophy (Benign Focal Amyotrophy) information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS). ]

Motor Neurone Disease - A site to provide resources, links and information about Motor Neurone Disease (MND)

Reading and West Berkshire MND Association - Information, news and contacts for people living with Motor Neurone Disease in Berkshire.

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