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The motor neurone diseases (MND) are a group of progressive neurological disorders that destroy motor neurones, the cells that control voluntary muscle activity such as speaking, walking, breathing, and swallowing. Amyotrophic lateral sclerosis (ALS), sometimes called Lou Gehrig's disease, progressive muscular atrophy (PMA), spinal muscular atrophy (SMA), progressive or pseudo-bulbar palsy (PBP) and primary lateral sclerosis (PLS) are all forms of motor neurone disease.

Terminology


In this article, MND refers to a group of diseases which affect the motor neurones. In the United States, the term ALS is more commonly used, where it is also known as Lou Gehrig's disease, after the baseball player. Although previously described by other neurologists of the 19th century, it was Jean-Martin Charcot, a French neurologist, who suggested grouping together a number of disparate conditions all affecting the lateral horn of the spinal cord in 1869. In France the disease is sometimes known as Maladie de Charcot (Charcot's disease), although it may also be referred to by the direct translation of ALS, Sclerose Laterale Amyotrophique (SLA). To help prevent confusion, the annual scientific research conference dedicated to the study of MND is called the International ALS/MND Symposium.

Signs and symptoms


Neurological examination presents specific signs associated with upper and lower motor neurone degeneration. Signs of upper motor neurone damage include spasticity, brisk reflexes and the Babinski sign. Signs of lower motor neurone damage include weakness and muscle atrophy.

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Posted ALS Update Motor neuron disease: systematic reviews of treatment for ALS and SMA.: http://bit.ly/6Km9Ss
NeuroTweeter (NeuroTweeter) Fri, 18 Dec 2009 09:44:21 -0000
Posted ALS Update Motor neuron disease: systematic reviews of treatment for ALS and SMA.: http://bit.ly/6Km9Ss
http://twitpic.com/tn6in - went for a drink here at the weekend trying to come up with ideas for a Motor Neuron Disease awareness campaign w
mr_hopkinson (David Hopkinson) Tue, 15 Dec 2009 19:00:57 -0000
http://twitpic.com/tn6in - went for a drink here at the weekend trying to come up with ideas for a Motor Neuron Disease awareness campaign w
Detailed Information on Motor Neuron Disease (http://bit.ly/84bNCt) http://bit.ly/84bNCt
inforeading (Goran) Mon, 14 Dec 2009 07:09:35 -0000
Detailed Information on Motor Neuron Disease (http://bit.ly/84bNCt) http://bit.ly/84bNCt
Shocked to learn my ex boyfriend has been diagnosed with Motor Neuron Disease- the odds! 4/ 100 000...so cruel!
maverickwoman (Annalie Killian) Sat, 12 Dec 2009 09:54:25 -0000
Shocked to learn my ex boyfriend has been diagnosed with Motor Neuron Disease- the odds! 4/ 100 000...so cruel!

 
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Amyotrophic Lateral Sclerosis Fact Sheet - A fact sheet about symptoms, diagnosis, treatment, and research on ALS, Motor Neuron Disease, or Lou Gehrig's Disease from the National Institute of Neurological Disorders and Stroke.

Amyotrophic Lateral Sclerosis: Lou Gehrig's Disease - Good article by the American Academy of Family Physicians.

Kennedy's Disease Association - Information about Kennedy's Disease, Symptoms, Chat, Forum.

Monomelic Amyotrophy - Information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS).
Meta Description: [ Monomelic amyotrophy (Benign Focal Amyotrophy) information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS). ]

Motor Neurone Disease - A site to provide resources, links and information about Motor Neurone Disease (MND)

Reading and West Berkshire MND Association - Information, news and contacts for people living with Motor Neurone Disease in Berkshire.

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