Gourt > Health > Conditions and Diseases > Neurological Disorders > Demyelinating Diseases > Leukodystrophy (4)
Leukodystrophy refers to progressive degeneration of the white matter of the brain due to imperfect growth or development of the myelin sheath, the fatty covering that acts as an insulator around nerve fiber. Myelin, which lends its color to the white matter of the brain, is a complex substance made up of at least ten different chemicals. The leukodystrophies are a group of disorders that are caused by genetic defects in how myelin produces or metabolizes these chemicals. Each of the leukodystrophies is the result of a defect in the gene that controls one (and only one) of the chemicals.
Types
Specific leukodystrophies include (ICD-10 codes are provided where available):
- (E71.3) adrenoleukodystrophy
- (E75.2) metachromatic leukodystrophy
- (E75.2) Krabbe disease
- (E75.2) Pelizaeus-Merzbacher disease
- Canavan disease
- childhood ataxia with central hypomyelination (CACH or vanishing white matter disease)
- Alexander disease
- (G60.1) Refsum disease
- cerebrotendineous xanthomatosis
How do you get leukodystrophy?
Leukodystrophies are mostly inherited disorders, meaning that it is passed on from parent to child. They may be inherited in a recessive, dominant, or X-linked manner, depending on the type of leukodystrophy. The individual pages on each leukodystrophy will describe the particular pattern of inheritance for that disease. There is also a separate fact sheet describing the different genetic inheritance patterns available from the United Leukodystrophy Foundation. More on [ Leukodystrophy ]
Genetic Disorders
Causes :: Mental Retardation
The Official Parent's Sourcebook on Metachromatic Leukodystrophy: A Revised and Updated Directory for the In... $28.95 http://bit.ly/4QWfir
eBookieCookie (eBookieCookie) Thu, 26 Nov 2009 01:47:54 -0000
The Official Parent's Sourcebook on Metachromatic Leukodystrophy: A Revised and Updated Directory for the In... $28.95 http://bit.ly/4QWfir
natural history of infantile globoid cell leukodystrophy http://bit.ly/4QzLFV
usclinicaltrial (US Clinical Trials) Tue, 24 Nov 2009 00:33:28 -0000
natural history of infantile globoid cell leukodystrophy http://bit.ly/4QzLFV
natural history of infantile globoid cell leukodystrophy http://bit.ly/4QzLFV
recruitingtrial (Recruiting Trials) Mon, 23 Nov 2009 23:49:12 -0000
natural history of infantile globoid cell leukodystrophy http://bit.ly/4QzLFV
Jocelyn is Wish #11. She has a condition called Leukodystrophy that affects her mental & physical development. Let's get her to Disney!
KJonair (KJ) Thu, 19 Nov 2009 18:43:43 -0000
Jocelyn is Wish #11. She has a condition called Leukodystrophy that affects her mental & physical development. Let's get her to Disney!
Aicardi-Goutieres Syndrome - News, descriptions, contacts, and other information concerning this leukodystrophy.
Meta Description: [ Website about Aicard-Goutières syndrome for families ! ]
Alexander Disease - Information sheet compiled by NINDS, the National Institute of Neurological Disorders and Stroke.
Meta Description: [ Alexander Disease information sheet compiled by NINDS. ]
Devoted to Brianna - Medical experiences and terminology helpful for parents to understand and cope with genetic disorders. One little girl's story, concerning Canavan Leukodystrophy offers help and hope to many.
Dylan Samuel Freeman - Dylan has a very rare neurological disorder, Alexanders disease (Leukodystrophy). His story, his progress, and photographs.
Family Village / Library / Leukodystrophy - Resources on Adrenoleukodystrophy, Alexander Disease, Canavan Disease, Krabbes Disease, Metachromatic Leukodystrophy, and Refsum's Disease.
Joe Johnson and the Call Again Soon BBS - Directed at making life better for people affected by Leukodystrophy and those who know and love them.
Leukodystrophy - CHORUS document on the different types of Leukodystrophy. A little technical.
Meta Description: [ a CHORUS notecard document about leukodystrophy ]
Leukodystrophy - A short information sheet compiled by NINDS, the National Institute of Neurological Disorders and Stroke.
Meta Description: [ Leukodystrophy information sheet compiled by NINDS. ]
MCW HealthLink - Alexander Disease - Information sheet from the Medical College of Wisconsin.
Meta Description: [ Alexander disease is a rare, genetic, degenerative disorder of the nervous system. ]
Undiagnosed Leukodystrophy - Lauren's homepage, a six year old from Melbourne, Australia with an as yet undiagnosed neurological condition thought to be genetic.
United Leukodystrophy Foundation - Nonprofit, voluntary health organization dedicated to providing patients and their families with information about their disease and assistance in their health.
Meta Description: [ United Leukodystrophy Foundation: The leukodystrophies are = genetically
determined progressive disorders that affect the brain, = spinal cord and
peripheral nerves. The term leukodystrophy derives from = the Greek words
"leuko" meaning white and referrin ]
| Story of Judson | |
| Next Video | |
