Gourt > Health > Conditions and Diseases > Neurological Disorders > Dementia > Lewy Body
Lewy bodies are abnormal aggregates of protein that develop inside nerve cells.
They are identified under the microscope when histology is performed on the brain. They appear as spherical masses that displace other cell components. There are two morphological types: classical (brain stem) Lewy bodies and cortical Lewy bodies. A classical Lewy body is an eosinophilic cytoplasmic inclusion that consists of a dense core surrounded by a halo of 10-nm wide radiating fibrils, the primary structural component of which is alpha-synuclein. In contrast, a cortical Lewy body is less well-defined and lacks the halo. Nonetheless, it is still made up of alpha-synuclein fibrils.
Cell biology
A Lewy body is composed of the protein alpha-synuclein associated with other proteins such as ubiquitin, neurofilament protein, and alpha B crystallin. It is believed that Lewy bodies represent an aggresomal response in the cell. More on [ Lewy body ]
Alzheimer's disease
Parkinson's Disease :: Neurological Disorders
Mental Health (Other)>What is dementia with Lewy bodies (DLB)? http://t.co/PkjluwQl
MHManura (Dr Nanayakkara) Sun, 05 Feb 2012 06:55:29 -0000
Mental Health (Other)>What is dementia with Lewy bodies (DLB)? http://t.co/PkjluwQl
Mental Health (Other)>What is dementia with Lewy bodies (DLB)? http://t.co/3sFTsVJC
njnuwantha (Dr Nuwan Nanayakkara) Sun, 05 Feb 2012 02:39:33 -0000
Mental Health (Other)>What is dementia with Lewy bodies (DLB)? http://t.co/3sFTsVJC
Mental Health (Other)>What is dementia with Lewy bodies (DLB)? http://t.co/rPlovj1x
ManuraNanayakka (Manura Nanayakkara) Sat, 04 Feb 2012 22:31:18 -0000
Mental Health (Other)>What is demen
Ageless Design - Ask The Experts - Activities - Discussion of the disease.
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Alpha-synuclein in Lewy Body Disease and Alzheimer's Disease - A discussion of the pathogenesis of the disease.[PDF Format]
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Lewy Body Dementia - Diagnosis criteria and symptoms for the disease.
Lewy Body Dementia Directory - Links and an e-group.
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Lewy Body Disease - Article discussing the disease by Tamara A. Smith, MD, and Richard A. Prayson.
Meta Description: [ The Southern Medical Association enables physicians to practice the highest standards of medicine by fostering professional development and economic stability through education, services, collegiality, and leadership across multiple specialties. ]
Lewy Body Disease - Short FAQ regarding the disease.
Lewy Body Disease Association - Patient and family support. Research and education information.
Meta Description: [ The Lewy Body Dementia Association is a site for the support and education of people with Lewy Body Dementia aka Lewy Body Disease (LBD) aka Louie Body Dementia aka Louie Body Disease and their caregivers. ]
Lewy Body Journal - A journal detailing the effects of LBD on a mother and how her family cares for her.
Meta Description: [ A journal detailing the effects of Lewy body disease on our mother and how our family cared for her; also a description of Lewy body disease, informational topics, and links to resources. ]
LewyNet - Detailed information on dementia with Lewy bodies, from the University of Nottingham, UK.
NINDS Dementia with Lewy Bodies Information - Compiled by the National Institute of Neurological Disorders and Stroke. Includes basic information and support organizations.
Meta Description: [ Dementia With Lewy Bodies information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS). ]
Pick's Disease Support Group - Lewy Body Dementia - Discussion of the characteristics of the disease.
Research: Alzheimer's and Lewy Body Disease: Important Similarities and Differences - Research at Alzheimer's Association Greater San Francisco Bay Area Chapter.
