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Ataxia (from Greek ataxiā, meaning failure to put in order) is unsteady and clumsy motion of the limbs or trunk due to a failure of the gross coordination of muscle movements.

Ataxia often occurs when parts of the nervous system that control movement are damaged. People with ataxia experience a failure of muscle control in their arms and legs, resulting in a lack of balance and coordination or a disturbance of gait. While the term ataxia is primarily used to describe this set of symptoms, it is sometimes also used to refer to a family of disorders. It is not, however, a specific diagnosis.

Most disorders that result in ataxia cause cells in the part of the brain called the cerebellum to degenerate, or atrophy. Sometimes the spine is also affected. The phrases cerebellar degeneration and spinocerebellar degeneration are used to describe changes that have taken place in a person’s nervous system; neither term constitutes a specific diagnosis. Cerebellar and spinocerebellar degeneration have many different causes. The age of onset of the resulting ataxia varies depending on the underlying cause of the degeneration.

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Genetic Disorders
Neurologic Manifestations :: Neurological Disorders
Spinocerebellar Degenerations
Rare Disorders :: Conditions and Diseases

 
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National Institutes of Health (NIH) News Releases

Schizophrenia and Bipolar Disorder Share Genetic Roots
Wed, 01 Jul 2009 15:45:00 -0400
A trio of genome-wide studies -- collectively the largest to date -- have pinpointed a vast array of genetic variation that cumulatively may account for at least one third of the genetic risk for schizophrenia. One of the studies traced schizophrenia and bipolar disorder, in part, to the same chromosomal neighborhoods.
Imaging Technique Allows Researchers to Monitor Protein Changes in Mouse Tumors
Wed, 01 Jul 2009 12:05:00 -0400
A new imaging technique can monitor, in living mice, the HER2 protein found in above-normal amounts in many cases of breast cancer as well as some ovarian, prostate and lung cancers. This new approach, once validated in mice and pending further experiments, could provide a real-time noninvasive method for identifying tumors in humans who express HER2 and who would be candidates for targeted therapy directed against this protein. It may also provide real-time information that will help clinicians optimize treatment for individual patients. The study, published in the July 2009 issue of The Journal of Nuclear Medicine, was conducted by researchers at the National Cancer Institute (NCI) and the National Institute of Biomedical Imaging and Bioengineering, both parts of the National Institutes of Health.
Dynasty: Influenza Virus in 1918 and Today
Tue, 30 Jun 2009 09:10:00 -0400
The influenza virus that wreaked worldwide havoc in 1918-1919 founded a viral dynasty that persists to this day, according to scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. In an article published online on June 29 by the New England Journal of Medicine, authors Anthony S. Fauci, M.D., Jeffery K. Taubenberger, M.D., Ph.D., and David M. Morens, M.D., argue that we have lived in an influenza pandemic era since 1918, and they describe how the novel 2009 H1N1 virus now circling the globe is yet another manifestation of this enduring viral family.

CNN.com - Health

Police: Hospital worker swiped shots, spread hep C
Fri, 03 Jul 2009 18:18:42 -0400
A former hospital employee may have exposed hundreds or thousands of surgical patients to hepatitis C when she replaced clean needles filled with the powerful painkiller fentanyl with her own dirty needles filled with saline solution.
Health.com picks top beach, lake getaways
Fri, 03 Jul 2009 13:47:40 -0400
We know your summer vacation time is precious: You want to land where you can truly relax, breathe fresh air, get in some exercise and eat well -- without breaking the bank. That's why we teamed up with a panel of travel and health experts to help us find the healthiest of the nation's most popular beach and lake towns.

 
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A-T Children's Project - A clearinghouse for ataxia-telangiectasia information, including disease information, scientific research, clinical and family support, and fundraising.

Ataxia Telangiectasia Society - Details about the organization which is committed to helping, supporting and advising families affected by AT. Includes research, support and awareness.
Meta Description: [ The A-T Society is a self-help group of families who have children with A-T. The objective of the A-T Society is to alliviate the distress and suffering that A-T causes., The A-T Society is a self-help group of families who have children with A-T. The objective of the A-T Society is to alliviate... ]

Ataxia UK - Charity offering help and support for people suffering from Friedrichs and cerebellar ataxia. Information on the disease, treatment and research.

Ataxia-Telangiectasia (A-T) Foundation - Information about the foundation's efforts to find a cure for A-T.
Meta Description: [ Ataxia-Telangiectasia is a rare disorder, the gene is one of the most important in the human genome. One in 100 people carry a defective copy of the A-T gene. Cancer susceptibility, including breast cancer, has been confirmed among A-T carriers. The disability is marked by immune system deficienc... ]

CajunHeart's HomePage - Living Life with Ataxia - Site about me living a positive life despite Friedreich's Ataxia.
Meta Description: [ an informative site about me and living a positive life in spite of having a progressive hereditary neurological disease called Friedreich's Ataxia. ]

Cathryn Dianne Achilles - Cathryn has Ataxia-telangiectasia. This is her story, along with some pictures.
Meta Description: [ Cathryn Achilles, 12 yrs old, has Ataxia-telangiectasia . Though this disease will take her life at an early age she has peace and joy because of her faith in Jesus Christ. ]

Cerebellar Ataxia Investigative Webpage - Offers information and a request for same via email.
Meta Description: [ If you or a loved one have been stricken with Ataxia, Cerebellar Ataxia, Cerebellar Degeneration - and are looking for the causative, this site may be helpful to you ]

Friedreich's Ataxia Fact Sheet - A comprehensive resources guide and fact sheet about Friedreich's Ataxia, compiled by NINDS, the National Institute of Neurological Disorders and Stroke.

Matthew Law - A personal web site about a life with Friedreich's Ataxia.

National Ataxia Foundation - Information about and support for people with ataxia.

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